Lupus Nephritis: Glycogen Synthase Kinase 3β Promotion of Renal Damage Through Activation of the NLRP3 Inflammasome in Lupus-Prone Mice

P2X7Blockade Attenuates Murine Lupus Nephritis by Inhibiting Activation of the NLRP3/ASC/Caspase 1 Pathway

(2013) Jijun Zhao et al.   ARTHRITIS AND RHEUMATISM

GSK-3 inhibition: Achieving moderate efficacy with high selectivity

(2013) Limor Avrahami et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Innate receptors for adaptive immunity

(2013) Marie-Cécile Michallet et al.   CURRENT OPINION IN MICROBIOLOGY

Bay11-7082 attenuates murine lupus nephritis via inhibiting NLRP3 inflammasome and NF-κB activation

(2013) Jijun Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inhibition of glycogen synthase kinase-3β suppresses inflammatory responses in rheumatoid arthritis fibroblast-like synoviocytes and collagen-induced arthritis

(2013) Yong-Jin Kwon et al.   JOINT BONE SPINE

Regulation of Th1 Cells and Experimental Autoimmune Encephalomyelitis by Glycogen Synthase Kinase-3

(2013) E. Beurel et al.   JOURNAL OF IMMUNOLOGY

Self Double-Stranded (ds)DNA Induces IL-1  Production from Human Monocytes by Activating NLRP3 Inflammasome in the Presence of Anti-dsDNA Antibodies

(2013) M. S. Shin et al.   JOURNAL OF IMMUNOLOGY

IFIT2 Is an Effector Protein of Type I IFN-Mediated Amplification of Lipopolysaccharide (LPS)-Induced TNF-  Secretion and LPS-Induced Endotoxin Shock

(2013) A. Siegfried et al.   JOURNAL OF IMMUNOLOGY

Rituximab treatment in lupus nephritis – where do we stand?

(2013) I Gunnarsson et al.   LUPUS

An Essential Role of Caspase 1 in the Induction of Murine Lupus and Its Associated Vascular Damage

(2013) J. Michelle Kahlenberg et al.   Arthritis & Rheumatology

Lupus nephritis: A critical review

(2012) Andrea T. Borchers et al.   AUTOIMMUNITY REVIEWS

Small molecules in the treatment of systemic lupus erythematosus

(2012) Anastasia Markopoulou et al.   CLINICAL IMMUNOLOGY

New developments in Toll-like receptor targeted therapeutics

(2012) Dympna J Connolly et al.   CURRENT OPINION IN PHARMACOLOGY

U1-Small Nuclear Ribonucleoprotein Activates the NLRP3 Inflammasome in Human Monocytes

(2012) M. S. Shin et al.   JOURNAL OF IMMUNOLOGY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation

(2011) Pei-Yi Tsai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glycogen synthase kinase 3 involvement in the excessive proinflammatory response to LPS in patients with decompensated cirrhosis

(2011) Nicolas Coant et al.   JOURNAL OF HEPATOLOGY

Reversing interleukin-2 inhibition mediated by anti-double-stranded DNA autoantibody ameliorates glomerulonephritis in MRL-lpr/lpr mice

(2010) Ying-Chyi Song et al.   ARTHRITIS AND RHEUMATISM

Using Small Molecule GSK3β Inhibitors to Treat Inflammation

(2010) G. Klamer et al.   CURRENT MEDICINAL CHEMISTRY

Suppressive Regulatory T Cell Activity Is Potentiated by Glycogen Synthase Kinase 3β Inhibition

(2010) Jay A. Graham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycogen Synthase Kinase-3 Is an Early Determinant in the Differentiation of Pathogenic Th17 Cells

(2010) E. Beurel et al.   JOURNAL OF IMMUNOLOGY

Adenosine 2A receptor is protective against renal injury in MRL/lpr mice

(2010) L Zhang et al.   LUPUS

Staphylococcus aureus Induces Microglial Inflammation via a Glycogen Synthase Kinase 3 -Regulated Pathway

(2009) Y.-L. Cheng et al.   INFECTION AND IMMUNITY

Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflammation-induced neurotoxicity

(2008) Christopher J. Yuskaitis et al.   CELLULAR SIGNALLING