Adenovirally-Induced Polyfunctional T Cells Do Not Necessarily Recognize the Infected Target: Lessons from a Phase I Trial of the AERAS-402 Vaccine

CD8 T cells and Mycobacterium tuberculosis infection

(2015) Philana Ling Lin et al.   Seminars in Immunopathology

The safety and immunogenicity of an adenovirus type 35-vectored TB vaccine in HIV-infected, BCG-vaccinated adults with CD4+ T cell counts >350 cells/mm3

(2015) Gavin John Churchyard et al.   VACCINE

A double-blind, randomised, placebo-controlled, dose-finding trial of the novel tuberculosis vaccine AERAS-402, an adenovirus-vectored fusion protein, in healthy, BCG-vaccinated infants

(2015) M. Tameris et al.   VACCINE

High-frequency vaccine-induced CD8+T cells specific for an epitope naturally processed during infection withMycobacterium tuberculosisdo not confer protection

(2014) Thomas Lindenstrøm et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Protective CD4 T Cells Targeting Cryptic Epitopes of Mycobacterium tuberculosis Resist Infection-Driven Terminal Differentiation

(2014) J. S. Woodworth et al.   JOURNAL OF IMMUNOLOGY

In search of a new paradigm for protective immunity to TB

(2014) Cláudio Nunes-Alves et al.   NATURE REVIEWS MICROBIOLOGY

Human Lung Epithelial Cells Contain Mycobacterium tuberculosis in a Late Endosomal Vacuole and Are Efficiently Recognized by CD8+ T Cells

(2014) Melanie J. Harriff et al.   PLoS One

The novel tuberculosis vaccine, AERAS-402, is safe in healthy infants previously vaccinated with BCG, and induces dose-dependent CD4 and CD8T cell responses

(2014) Benjamin M.N. Kagina et al.   VACCINE

CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomized Trials

(2013) Kenneth F. Schulz   ANNALS OF INTERNAL MEDICINE

The Immune Response in Tuberculosis

(2013) Anne O'Garra et al.   Annual Review of Immunology

Inhibition of Mycobacterial GrowthIn Vitrofollowing Primary but Not Secondary Vaccination with Mycobacterium bovis BCG

(2013) Helen A. Fletcher et al.   Clinical and Vaccine Immunology

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

(2013) Michele D Tameris et al.   LANCET

Human Mycobacterium tuberculosis CD8 T Cell Antigens/Epitopes Identified by a Proteomic Peptide Library

(2013) David M. Lewinsohn et al.   PLoS One

The current state of tuberculosis vaccines

(2013) David A Hokey et al.   Human Vaccines & Immunotherapeutics

Prospects for Tuberculosis Elimination

(2012) Christopher Dye et al.   Annual Review of Public Health

The immunoproteasome in antigen processing and other immunological functions

(2012) Michael Basler et al.   CURRENT OPINION IN IMMUNOLOGY

A recombinant adenovirus expressing immunodominant TB antigens can significantly enhance BCG-induced human immunity

(2012) Daniel F. Hoft et al.   VACCINE

CD8+T Cells Provide an Immunologic Signature of Tuberculosis in Young Children

(2011) Christina Lancioni et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Views of immunology: effector T cells

(2011) Deborah A. Lewinsohn et al.   IMMUNOLOGICAL REVIEWS

Fact and fiction in tuberculosis vaccine research: 10 years later

(2011) Stefan HE Kaufmann   LANCET INFECTIOUS DISEASES

The Novel Tuberculosis Vaccine, AERAS-402, Induces Robust and Polyfunctional CD4+and CD8+T Cells in Adults

(2010) Brian Abel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns

(2010) Benjamin M. N. Kagina et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Polyfunctional T cells in human tuberculosis

(2010) Katalin A. Wilkinson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

(2010) Marielle C. Gold et al.   PLOS BIOLOGY

Cell-Mediated Immune Responses in Tuberculosis

(2009) Andrea M. Cooper   Annual Review of Immunology

Quality and Vaccine Efficacy of CD4+ T Cell Responses Directed to Dominant and Subdominant Epitopes in ESAT-6 from Mycobacterium tuberculosis

(2009) C. S. Aagaard et al.   JOURNAL OF IMMUNOLOGY

Tuberculosis Subunit Vaccination Provides Long-Term Protective Immunity Characterized by Multifunctional CD4 Memory T Cells

(2009) T. Lindenstrom et al.   JOURNAL OF IMMUNOLOGY