BIX01294, an inhibitor of histone methyltransferase, induces autophagy-dependent differentiation of glioma stem-like cells
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Title
BIX01294, an inhibitor of histone methyltransferase, induces autophagy-dependent differentiation of glioma stem-like cells
Authors
Keywords
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Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-12-09
DOI
10.1038/srep38723
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Note: Only part of the references are listed.- Inhibition of H3K9 methyltransferase G9a induces autophagy and apoptosis in oral squamous cell carcinoma
- (2015) Aishu Ren et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cancer stem cells in glioblastoma
- (2015) Justin D. Lathia et al. GENES & DEVELOPMENT
- Retinoid resistance and multifaceted impairment of retinoic acid synthesis in glioblastoma
- (2015) Benito Campos et al. GLIA
- Cannabidiol stimulates Aml-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2-dependent manner
- (2015) Massimo Nabissi et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of G9a Histone Methyltransferase Converts Bone Marrow Mesenchymal Stem Cells to Cardiac Competent Progenitors
- (2015) Jinpu Yang et al. Stem Cells International
- The Selective Activation of p53 Target Genes Regulated by SMYD2 in BIX-01294 Induced Autophagy-Related Cell Death
- (2015) Jia-Dong Fan et al. PLoS One
- Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells
- (2014) Mario L. Suvà et al. CELL
- Glioblastoma Stem-Like Cells – Isolation, Biology and Mechanisms of Chemotherapy Resistance
- (2014) Iwona Ciechomska et al. Current Signal Transduction Therapy
- Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy
- (2014) K. Yan et al. GENES & DEVELOPMENT
- Euchromatic histone methyltransferase 2 inhibitor, BIX-01294, sensitizes human promyelocytic leukemia HL-60 and NB4 cells to growth inhibition and differentiation
- (2014) Jurate Savickiene et al. LEUKEMIA RESEARCH
- Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells
- (2014) Hong Tao et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Responsiveness of stem-like human glioma cells to all-trans retinoic acid and requirement of retinoic acid receptor isotypes α, β and γ
- (2014) I. Choschzick et al. NEUROSCIENCE
- The effects of selected inhibitors of histone modifying enzyme on C6 glioma cells
- (2014) Marta Maleszewska et al. Pharmacological Reports
- Inhibition of H3K9 Methyltransferase G9a Repressed Cell Proliferation and Induced Autophagy in Neuroblastoma Cells
- (2014) Xiao-Xue Ke et al. PLoS One
- Suberoylanilide hydroxamic acid (SAHA) causes tumor growth slowdown and triggers autophagy in glioblastoma stem cells
- (2013) Ming-Tsang Chiao et al. Autophagy
- BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production
- (2013) Yunha Kim et al. Autophagy
- Autophagy in stem cells
- (2013) Jun-Lin Guan et al. Autophagy
- Epigenetic Regulation of Autophagy by the Methyltransferase G9a
- (2013) A. Artal-Martinez de Narvajas et al. MOLECULAR AND CELLULAR BIOLOGY
- The return of the nucleus: transcriptional and epigenetic control of autophagy
- (2013) Jens Füllgrabe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells
- (2012) Patricia Vázquez et al. Autophagy
- Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging
- (2012) Kanchan Phadwal et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Endothelial differentiation of adipose-derived mesenchymal stem cells is improved by epigenetic modifying drug BIX-01294
- (2012) Mihaela Culmes et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- A restricted cell population propagates glioblastoma growth after chemotherapy
- (2012) Jian Chen et al. NATURE
- Endoplasmic reticulum stress triggers autophagy in malignant glioma cells undergoing cyclosporine A-induced cell death
- (2012) I A Ciechomska et al. ONCOGENE
- Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells
- (2012) C Gong et al. ONCOGENE
- Lysine methyltransferase G9a methylates the transcription factor MyoD and regulates skeletal muscle differentiation
- (2012) B. M. T. Ling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Histone Methyltransferase Inhibitor BIX01294 Enhances the Cardiac Potential of Bone Marrow Cells
- (2012) Nadejda V. Mezentseva et al. STEM CELLS AND DEVELOPMENT
- BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression
- (2012) L Persano et al. Cell Death & Disease
- Autophagy and cancer therapy
- (2011) Paola Maycotte et al. CANCER BIOLOGY & THERAPY
- Targeting glioma stem cells: A novel framework for brain tumors
- (2011) Emanuela Binello et al. CANCER SCIENCE
- Curcumin promotes differentiation of glioma-initiating cells by inducing autophagy
- (2011) Wenzhuo Zhuang et al. CANCER SCIENCE
- Autophagy is required for self-renewal and differentiation of adult human stem cells
- (2011) Souzan Salemi et al. CELL RESEARCH
- Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity
- (2011) Wenzhuo Zhuang et al. INTERNATIONAL JOURNAL OF CANCER
- Valproic Acid Induced Differentiation and Potentiated Efficacy of Taxol and Nanotaxol for Controlling Growth of Human Glioblastoma LN18 and T98G Cells
- (2011) Subhasree Roy Choudhury et al. NEUROCHEMICAL RESEARCH
- Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition
- (2011) M Ying et al. ONCOGENE
- Autophagy in Stem Cell Maintenance and Differentiation
- (2011) Alexandre Teixeira Vessoni et al. STEM CELLS AND DEVELOPMENT
- Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells
- (2010) Sridhar Reddy Chirasani et al. BRAIN
- Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis
- (2010) S. Mazzoleni et al. CANCER RESEARCH
- Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells
- (2010) B. Campos et al. CLINICAL CANCER RESEARCH
- Immunobiological Characterization of Cancer Stem Cells Isolated from Glioblastoma Patients
- (2010) T. Di Tomaso et al. CLINICAL CANCER RESEARCH
- Brain tumor stem cells: The cancer stem cell hypothesis writ large
- (2010) Peter B. Dirks Molecular Oncology
- Autophagy in mammalian development and differentiation
- (2010) Noboru Mizushima et al. NATURE CELL BIOLOGY
- Cancer stem cells in glioblastoma—molecular signaling and therapeutic targeting
- (2010) Zhi Huang et al. Protein & Cell
- Autophagy impairment inhibits differentiation of glioma stem/progenitor cells
- (2009) Yaodong Zhao et al. BRAIN RESEARCH
- Mammalian autophagy: core molecular machinery and signaling regulation
- (2009) Zhifen Yang et al. CURRENT OPINION IN CELL BIOLOGY
- The induction of autophagy by γ-radiation contributes to the radioresistance of glioma stem cells
- (2009) Stephanie L. Lomonaco et al. INTERNATIONAL JOURNAL OF CANCER
- Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
- (2009) Roger Stupp et al. LANCET ONCOLOGY
- Epigenetic-Mediated Dysfunction of the Bone Morphogenetic Protein Pathway Inhibits Differentiation of Glioblastoma-Initiating Cells
- (2008) Jeongwu Lee et al. CANCER CELL
- Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds
- (2008) Yan Shi et al. Cell Stem Cell
- Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells
- (2007) Mei Zeng et al. CELLULAR SIGNALLING
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