Article
Multidisciplinary Sciences
Frank A. J. L. Scheer, Michael F. Hilton, Heather L. Evoniuk, Sally A. Shiels, Atul Malhotra, Rena Sugarbaker, R. Timothy Ayers, Elliot Israel, Anthony F. Massaro, Steven A. Shea
Summary: The study found that asthma patients experience worsened lung function and exacerbation of symptoms at night, often masked by sleep. Asthma patients exhibit significant circadian rhythms throughout the day and are more likely to use bronchodilators during the night.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Review
Physiology
Anna-Marie Finger, Achim Kramer
Summary: The endogenous circadian clock system in humans and other mammals is crucial for health, but modern lifestyles with artificial lighting, shift work, and travel across time zones can disrupt this system and lead to associated diseases. This review highlights the importance of a functional clock machinery and alignment between body clocks, as well as the impact of circadian disruption on health.
Review
Neurosciences
Elena Gangitano, Lucio Gnessi, Andrea Lenzi, David Ray
Summary: Circadian rhythms play a crucial role in physiological processes and are influenced by light-dark cycles and food intake. Misalignment of circadian clocks may lead to metabolic diseases, highlighting the significance of diet and fasting on clock regulation.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Clinical Neurology
Sara Gamboa Madeira, Catia Reis, Teresa Paiva, Carlos Santos Moreira, Paulo Nogueira, Till Roenneberg
Summary: This study found that each additional hour of social jetlag increased the risk of high cardiovascular risk by more than 30%, highlighting the importance of sleep and individual circadian qualities in preventing negative health impacts of shift work.
JOURNAL OF SLEEP RESEARCH
(2021)
Article
Biochemical Research Methods
Jaskaran Singh, Yingzhou Edward Pan, Shunmoogum A. Patten
Summary: This study developed an ImageJ macro called NMJ Analyser to automatically and unbiasedly analyze the structural morphology of neuromuscular junctions in zebrafish. The macro can extract and quantify terminal structures from zebrafish images, providing valuable insights for the study of neuromuscular diseases and developmental neurobiology.
Article
Engineering, Environmental
Weijian Ding, Kexin Ma, Amy E. Childress
Summary: This study introduces a novel method to quantify the compaction of membranes under low pressure by combining electrical impedance spectroscopy with dynamic mechanical analysis. Results indicate that the initial instant compaction contributes more to total compaction than subsequent instant compaction. The method shows promise for detecting and predicting performance and fatigue of water treatment membranes.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2023)
Article
Biochemistry & Molecular Biology
Erica C. Jansen, Dana Dolinoy, Karen E. Peterson, Louise M. O'Brien, Ronald D. Chervin, Alejandra Cantoral, Martha Maria Tellez-Rojo, Maritsa Solano-Gonzalez, Jaclyn Goodrich
Summary: The study found that later sleep timing was significantly associated with higher DNA methylation of several circadian genes, and different dietary patterns were also related to circadian gene DNA methylation, with the "breakfast" pattern having the clearest inverse associations. These findings suggest that timing-related sleep and eating behaviors among adolescents could result in epigenetic modification of clock genes.
Article
Neurosciences
Brant P. Hasler, Jessica L. Graves, Adriane M. Soehner, Meredith L. Wallace, Duncan B. Clark
Summary: This study examined the relationship between sleep and circadian rhythm disturbances and alcohol use in late adolescents. The findings suggest that circadian misalignment is associated with reduced neural response to reward and patterns of problematic drinking.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Clinical Neurology
Arman Arab, Elham Karimi, Marta Garaulet, Frank A. J. L. Scheer
Summary: The objective of this systematic review was to examine the association between social jetlag and diet using observational studies. A total of 17 studies with a sample size of 28,905 were included in the review. The findings suggest a negative association between social jetlag and adherence to healthy eating habits, while the results regarding specific food groups and nutrients were mixed and controversial.
SLEEP MEDICINE REVIEWS
(2023)
Article
Biochemistry & Molecular Biology
Sarah L. Chellappa, Phillip A. Engen, Ankur Naqib, Jingyi Qian, Nina Vujovic, Nishath Rahman, Stefan J. Green, Marta Garaulet, Ali Keshavarzian, Frank A. J. L. Scheer
Summary: This study found that human oral microbiota has endogenous circadian rhythms and that circadian misalignment significantly affects the composition and functional pathways of the microbiota, particularly those related to metabolism and immune function. These findings have translational relevance for individuals exposed to circadian misalignment, such as night shift workers and frequent travelers.
Article
Nutrition & Dietetics
Rocco Caliandro, Astrid A. Streng, Linda W. M. van Kerkhof, Gijsbertus T. J. van der Horst, Ines Chaves
Summary: Social jetlag refers to the discrepancy between our internal body clock and social times, mainly driven by social obligations like work or school. Despite efforts to understand its effects on human health, our knowledge of social jetlag remains limited. Due to its prevalence, social jetlag is now a major concern for public health.
Article
Clinical Neurology
Marieve Cyr, Despina Z. Artenie, Alain Al Bikaii, Virginia Lee, Amir Raz, Jay A. Olson
Summary: Evening light exposure can reduce fatigue and errors in night-shift workers, improve mood, and enhance sleep quality.
Article
Psychology, Developmental
Maria Fernanda Zeron-Rugerio, Tannia Valeria Carpio-Arias, Estrella Ferreira-Garcia, Antoni Diez-Noguera, Trinitat Cambras, Jose Angel Alda, Maria Izquierdo-Pulido
Summary: This study aimed to investigate the circadian pattern of motor activity in children and adolescents newly diagnosed with ADHD, revealing that ADHD patients tend to have eveningness and more severe sleep disturbances. Patients with ADHD-combined subtype showed higher levels of motor activity, while those with ADHD-inattentive subtype exhibited more fragmented circadian patterns and increased BMI.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2021)
Article
Nutrition & Dietetics
Andrew W. McHill, Joseph T. Hull, Elizabeth B. Klerman
Summary: Chronic circadian disruption and insufficient sleep are independently associated with poor health outcomes. This study found that chronic circadian disruption was associated with decreased hunger and appetite, and these changes were correlated with changes in the ghrelin/leptin ratio.
Article
Endocrinology & Metabolism
Hylton E. Molzof, Courtney M. Peterson, S. Justin Thomas, Gabrielle F. Gloston, Russell L. Johnson, Karen L. Gamble
Summary: This study examined the differences in insulin and leptin levels between dayshift and nightshift nurses and explored the effects of meal timing on these levels in nightshift workers. The results showed that nightshift nurses had higher insulin and leptin levels compared to dayshift nurses, and eating predominantly at night was associated with even higher levels. The study concluded that although nightshift work increases insulin and leptin levels, eating during the daytime may attenuate some of the negative effects on metabolic health.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Clinical Neurology
Josef Fritz, Andrew J. K. Phillips, Larissa C. Hunt, Akram Imam, Kathryn J. Reid, Krista M. Perreira, Yasmin Mossavar-Rahmani, Martha L. Daviglus, Daniela Sotres-Alvarez, Phyllis C. Zee, Sanjay R. Patel, Celine Vetter
Summary: Sleep regularity is associated with diabetes risk, especially in older adults. Further research is needed to fully understand the impact of sleep regularity on metabolic disorders and pathophysiology.
Article
Respiratory System
Robert J. Maidstone, James Turner, Celine Vetter, Hassan S. Dashti, Richa Saxena, Frank A. J. L. Scheer, Steven A. Shea, Simon D. Kyle, Deborah A. Lawlor, Andrew S. Loudon, John F. Blaikley, Martin K. Rutter, David W. Ray, Hannah Jane Durrington
Summary: Shift work, especially night shifts, is associated with a higher likelihood of moderate-severe asthma. Individuals who engage in any type of shift work also have a higher risk of wheeze/whistling in the chest. Additionally, morning chronotypes working irregular shifts, including nights, are at an increased risk of moderate-severe asthma.
Article
Public, Environmental & Occupational Health
Iyas Daghlas, Rebecca C. Richmond, Jacqueline M. Lane, Hassan S. Dashti, Hanna M. Ollila, Eva S. Schernhammer, George Davey Smith, Martin K. Rutter, Richa Saxena, Celine Vetter
Summary: Genetically-instrumented liability to lower educational attainment and higher BMI may influence the selection into frequent shift work, with no mediation effect of sleep timing preference. This phenomenon may introduce bias in epidemiological studies of shift work conducted in the UK Biobank.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Biology
Dorothee Fischer, Till Roenneberg, Celine Vetter
Summary: The study found that consecutive night shifts should be limited for early chronotypes, while working four night shifts might be a beneficial alternative for other chronotypes. It is important to note that different chronotypes showed different levels of sleep debt under different shift sequences.
JOURNAL OF BIOLOGICAL RHYTHMS
(2021)
Review
Construction & Building Technology
Celine Vetter, P. Morgan Pattison, Kevin Houser, Michael Herf, Andrew J. K. Phillips, Kenneth P. Wright, Debra J. Skene, George C. Brainard, Diane B. Boivin, Gena Glickman
Summary: Architectural lighting has significant biological effects on human health, but current applied lighting practices are limited. This review consolidates key references and terminology, outlining the physiological effects of light and emphasizing the importance of translating laboratory knowledge into practical lighting strategies. Future research is needed to further support human health through integrative lighting solutions with high biological potency during the day and low potency during the night.
Article
Clinical Neurology
Ignacio Estevan, Bettina Tassino, Celine Vetter, Ana Silva
Summary: The research indicated that sleep behavior in adolescents is influenced by both circadian and homeostatic factors. During a period of extreme variability in social pressures, there was a significant association between light exposure and sleep behavior, with circadian factors having a greater impact on sleep duration than light exposure.
JOURNAL OF SLEEP RESEARCH
(2022)
Article
Endocrinology & Metabolism
Adnin Zaman, Kelsey J. Sloggett, Ann E. Caldwell, Victoria A. Catenacci, Marc-Andre Cornier, Laura Grau, Celine Vetter, Corey A. Rynders, Elizabeth A. Thomas
Summary: This study assessed the effects of the COVID-19 pandemic on weight loss intervention in adults with overweight or obesity. Despite disruptions caused by the pandemic, participants were able to achieve weight loss with continued behavioral support.
Article
Multidisciplinary Sciences
Philipp Burt, Saskia Grabe, Cornelia Madeti, Abhishek Upadhyay, Martha Merrow, Till Roenneberg, Hanspeter Herzel, Christoph Schmal
Summary: This study investigated the entrainment of the chronobiological model organism Neurospora crassa to thermocycles of different periods and fractions of warm versus cold phases, mimicking seasonal variations. Depending on the properties of these thermocycles, regularly entrained rhythms, period-doubling but also irregular aperiodic behavior were observed. The complex nonlinear phenomena of experimentally observed entrainment dynamics can be understood by molecular mathematical modeling.
Article
Nutrition & Dietetics
Siena C. Gioia, Melanie Guirette, Angela Chen, Chandler Tucker, Brianna E. Gray, Celine Vetter, Marta Garaulet, Frank A. J. L. Scheer, Richa Saxena, Hassan S. Dashti
Summary: There are currently no standard and low-cost methods to assess the timing of food intake. However, this study has validated simple, recall-based questions that can effectively characterize food timing in free-living populations.
CURRENT DEVELOPMENTS IN NUTRITION
(2022)
Article
Endocrinology & Metabolism
Gideon P. Dunster, Isabelle Hua, Alex Grahe, Jason G. Fleischer, Satchidananda Panda, Kenneth P. P. Wright Jr, Celine Vetter, Jennifer H. Doherty, Horacio O. de la Iglesia
Summary: Despite the availability of electric light, sleep timing is delayed during the winter. However, daily exposure to daylight can prevent this delayed phase of the circadian clock.
JOURNAL OF PINEAL RESEARCH
(2023)
Article
Clinical Neurology
Anthony J. Hand, Julia E. Stone, Lin Shen, Celine Vetter, Sean W. Cain, Bei Bei, Andrew J. K. Phillips
Summary: This study explores the relationship between sleep and light regularity in adolescents. New metrics for light regularity were developed and tested. The findings suggest that irregular sleep patterns are associated with irregular light inputs, potentially contributing to circadian disruption.
Article
Endocrinology & Metabolism
Marta Garaulet, Barbara Vizmanos, Teresa Muela, Alejandra Betancourt-Nunez, Maria-angeles Bonmati-Carrion, Celine Vetter, Hassan S. Dashti, Richa Saxena, Frank A. J. L. Scheer
Summary: This study aimed to investigate the relationship between being an evening type and reporting emotional eating behaviors. The results showed that evening types had higher scores on emotional eating and were more likely to be emotional eaters. They also scored higher on disinhibition/overeating and food craving factors. A meta-analysis revealed that being an evening type was associated with a higher score on emotional eating. Furthermore, individuals with late dim-light melatonin onset showed higher scores on emotional eating.
Article
Clinical Neurology
Johanna Ell, Julian E. Schiel, Bernd Feige, Dieter Riemann, Casandra C. Nyhuis, Julio Fernandez-Mendoza, Celine Vetter, Martin K. Rutter, Simon D. Kyle, Kai Spiegelhalder
Summary: This study examined the long-term effects of sleep health and shift work on cognitive performance in middle-aged and older adults using data from the UK Biobank. The results indicated that poor sleep health and shift work significantly predicted lower cognitive performance in this population.
Article
Clinical Neurology
Marina Gardesevic, Altug Didikoglu, Samuel J. D. Lawrence, Celine Vetter, Timothy M. Brown, Annette E. Allen, Robert J. Lucas
Summary: Light is a crucial regulator of behavioral and physiological state in mammals, and it can affect cognitive performance such as memory, vigilance, and alertness. However, the role of light as a regulator of performance in everyday life remains unclear. In this study, researchers developed an app called Brighter Time to measure cognitive performance and light exposure in everyday life. The app was able to reveal associations between task performance and sleepiness, time of day, and current illuminance. This study suggests that light plays an important role in regulating cognitive performance in everyday life.
Article
Psychology, Clinical
Layla J. Bunjo, Amy C. Reynolds, Sarah L. Appleton, Jill Dorrian, Celine Vetter, Tiffany K. Gill, Robert J. Adams
Summary: The study found that sleep duration moderates the relationship between work-life interference and depressive symptoms, with the strongest effect observed in habitual short sleepers. This relationship was observed in both male and female respondents, but was stronger in females. The study suggests that educating workers about the benefits of sleep could potentially improve worker well-being, especially in situations where work-life interference cannot easily be remedied.
INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE
(2021)