Autophagy is induced in the skeletal muscle of cachectic cancer patients

Autophagy: a druggable process that is deregulated in aging and human disease

(2015) Guido Kroemer   JOURNAL OF CLINICAL INVESTIGATION

Coming back

(2014) Fabio Penna et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy

(2014) Vladimir Rogov et al.   MOLECULAR CELL

Caloric restriction mimetics: towards a molecular definition

(2014) Frank Madeo et al.   NATURE REVIEWS DRUG DISCOVERY

Clinical Classification of Cancer Cachexia: Phenotypic Correlates in Human Skeletal Muscle

(2014) Neil Johns et al.   PLoS One

Autophagy Impairment in Muscle Induces Neuromuscular Junction Degeneration and Precocious Aging

(2014) Silvia Carnio et al.   Cell Reports

Autophagic-lysosomal pathway is the main proteolytic system modified in the skeletal muscle of esophageal cancer patients

(2013) Nicolas Tardif et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Nuclear transcription factor κ B activation and protein turnover adaptations in skeletal muscle of patients with progressive stages of lung cancer cachexia

(2013) Céline M Op den Kamp et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Autophagic Degradation Contributes to Muscle Wasting in Cancer Cachexia

(2013) Fabio Penna et al.   AMERICAN JOURNAL OF PATHOLOGY

Higher activation of autophagy in skeletal muscle of mice during endurance exercise in the fasted state

(2013) Cécile Jamart et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Autophagy in Locomotor Muscles of Patients with Chronic Obstructive Pulmonary Disease

(2013) Yeting Guo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome

(2013) Marco Sandri   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Skeletal muscle, autophagy, and physical activity: the ménage à trois of metabolic regulation in health and disease

(2013) Anna Vainshtein et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Altered Expression of DJ-1 and PINK1 in Sporadic ALS and in the SOD1G93AALS Mouse Model

(2013) Sarah Knippenberg et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Overexpression of Atg5 in mice activates autophagy and extends lifespan

(2013) Jong-Ok Pyo et al.   Nature Communications

Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial

(2013) Greet Hermans et al.   Lancet Respiratory Medicine

Denervation-induced mitochondrial dysfunction and autophagy in skeletal muscle of apoptosis-deficient animals

(2012) Michael F. N. O′Leary et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis

(2012) Jia Qiu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

(2012) Jose A. Martina et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Cellular and molecular mechanisms of muscle atrophy

(2012) P. Bonaldo et al.   Disease Models & Mechanisms

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

Early Parenteral Nutrition Evokes a Phenotype of Autophagy Deficiency in Liver and Skeletal Muscle of Critically Ill Rabbits

(2012) Sarah Derde et al.   ENDOCRINOLOGY

Muscle atrophy in aging and chronic diseases: is it sarcopenia or cachexia?

(2012) Maurizio Muscaritoli et al.   Internal and Emergency Medicine

Role of autophagy in COPD skeletal muscle dysfunction

(2012) Sabah N. A. Hussain et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mitochondrial biogenesis and fragmentation as regulators of protein degradation in striated muscles

(2012) Vanina Romanello et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The time course of the adaptations of human muscle proteome to bed rest and the underlying mechanisms

(2012) Lorenza Brocca et al.   JOURNAL OF PHYSIOLOGY-LONDON

Autophagy and Skeletal Muscles in Sepsis

(2012) Mahroo Mofarrahi et al.   PLoS One

Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI-deficient muscles

(2011) Paolo Grumati et al.   Autophagy

Autophagy in Lysosomal Myopathies

(2011) May Christine V. Malicdan et al.   BRAIN PATHOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Autophagy in the Cellular Energetic Balance

(2011) Rajat Singh et al.   Cell Metabolism

Definition and classification of cancer cachexia: an international consensus

(2011) Kenneth Fearon et al.   LANCET ONCOLOGY

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation

(2011) David G. McEwan et al.   TRENDS IN CELL BIOLOGY

Impaired Autophagy in Sporadic Inclusion-Body Myositis and in Endoplasmic Reticulum Stress-Provoked Cultured Human Muscle Fibers

(2010) Anna Nogalska et al.   AMERICAN JOURNAL OF PATHOLOGY

Quantitation of "autophagic flux" in mature skeletal muscle

(2010) Jeong-Sun Ju et al.   Autophagy

Overview of macroautophagy regulation in mammalian cells

(2010) Maryam Mehrpour et al.   CELL RESEARCH

Consensus definition of sarcopenia, cachexia and pre-cachexia: Joint document elaborated by Special Interest Groups (SIG) “cachexia-anorexia in chronic wasting diseases” and “nutrition in geriatrics”

(2010) M. Muscaritoli et al.   CLINICAL NUTRITION

The “parallel pathway”: a novel nutritional and metabolic approach to cancer patients

(2010) Maurizio Muscaritoli et al.   Internal and Emergency Medicine

Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration

(2010) Paolo Grumati et al.   NATURE MEDICINE

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond

(2010) Sarah F. Funderburk et al.   TRENDS IN CELL BIOLOGY

Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia

(2010) Nathan A Stephens et al.   Genome Medicine

In search of an “autophagomometer”

(2009) David C. Rubinsztein et al.   Autophagy

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Bnip3 functions as a mitochondrial sensor of oxidative stress during myocardial ischemia and reperfusion

(2008) Dieter A. Kubli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE