Assessing mutant p53 in primary high-grade serous ovarian cancer using immunohistochemistry and massively parallel sequencing

Molecular Alterations of TP53 are a Defining Feature of Ovarian High-Grade Serous Carcinoma

(2016) Russell Vang et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer

(2015) Adam R. Blanden et al.   DRUG DISCOVERY TODAY

Whole–genome characterization of chemoresistant ovarian cancer

(2015) Ann-Marie Patch et al.   NATURE

Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

(2015) Tan A. Ince et al.   Nature Communications

Clinical Validation of KRAS, BRAF, and EGFR Mutation Detection Using Next-Generation Sequencing

(2014) Ming-Tseh Lin et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Mutant p53 in Cancer: New Functions and Therapeutic Opportunities

(2014) Patricia A.J. Muller et al.   CANCER CELL

p53 as a target for the treatment of cancer

(2014) Michael J. Duffy et al.   CANCER TREATMENT REVIEWS

Clinical utility of recombinant adenoviral human p53 gene therapy: current perspectives

(2014) Guang-Xia Chen et al.   OncoTargets and Therapy

Quality of life and treatment response among women with platinum-resistant versus platinum-sensitive ovarian cancer treated for progression: A prospective analysis

(2013) Vanessa L. Beesley et al.   GYNECOLOGIC ONCOLOGY

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Increased detection rates of EGFR and KRAS mutations in NSCLC specimens with low tumour cell content by 454 deep sequencing

(2013) Evgeny A. Moskalev et al.   VIRCHOWS ARCHIV

Evaluating cell lines as tumour models by comparison of genomic profiles

(2013) Silvia Domcke et al.   Nature Communications

Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer

(2012) Casina WS Kan et al.   BMC CANCER

Targeting p53 in Vivo: A First-in-Human Study With p53-Targeting Compound APR-246 in Refractory Hematologic Malignancies and Prostate Cancer

(2012) Sören Lehmann et al.   JOURNAL OF CLINICAL ONCOLOGY

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis

(2012) Bernard Leroy et al.   NUCLEIC ACIDS RESEARCH

The Genomic Landscape of TP53 and p53 Annotated High Grade Ovarian Serous Carcinomas from a Defined Founder Population Associated with Patient Outcome

(2012) Paulina M. Wojnarowicz et al.   PLoS One

Immunohistochemical staining patterns of p53 can serve as a surrogate marker for TP53 mutations in ovarian carcinoma: an immunohistochemical and nucleotide sequencing analysis

(2011) Anna Yemelyanova et al.   MODERN PATHOLOGY

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Expression signatures of TP53 mutations in serous ovarian cancers

(2010) Marcus Q Bernardini et al.   BMC CANCER

p53 at a glance

(2010) C. A. Brady et al.   JOURNAL OF CELL SCIENCE

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary

(2010) Ahmed Ashour Ahmed et al.   JOURNAL OF PATHOLOGY

The biological and clinical value of p53 expression in pelvic high-grade serous carcinomas

(2010) Martin Köbel et al.   JOURNAL OF PATHOLOGY

Genomics: In search of rare human variants

(2010) Rasmus Nielsen   NATURE

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Modest effect of p53, EGFR and HER-2/neu on prognosis in epithelial ovarian cancer: a meta-analysis

(2009) P de Graeff et al.   BRITISH JOURNAL OF CANCER

Mutant p53 Gain-of-Function in Cancer

(2009) M. Oren et al.   Cold Spring Harbor Perspectives in Biology

The Origins and Evolution of the p53 Family of Genes

(2009) V. A. Belyi et al.   Cold Spring Harbor Perspectives in Biology

TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use

(2009) M. Olivier et al.   Cold Spring Harbor Perspectives in Biology

Distribution of p53 expression in tissue from 774 Danish ovarian tumour patients and its prognostic significance in ovarian carcinomas

(2008) ESTRID V. S. HØGDALL et al.   APMIS

Diagnostic Markers for Early Detection of Ovarian Cancer

(2008) I. Visintin et al.   CLINICAL CANCER RESEARCH

Serous Tubal Intraepithelial Carcinoma: Its Potential Role in Primary Peritoneal Serous Carcinoma and Serous Cancer Prevention

(2008) Joseph W. Carlson et al.   JOURNAL OF CLINICAL ONCOLOGY