Optogenetic activation of axon guidance receptors controls direction of neurite outgrowth

The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP

(2014) A. D. Norris et al.   DEVELOPMENT

The Crystal Structure of Netrin-1 in Complex with DCC Reveals the Bifunctionality of Netrin-1 As a Guidance Cue

(2014) Lorenzo I. Finci et al.   NEURON

Highly Effective Photonic Cue for Repulsive Axonal Guidance

(2014) Bryan J. Black et al.   PLoS One

Optogenetic protein clustering and signaling activation in mammalian cells

(2013) Lukasz J Bugaj et al.   NATURE METHODS

Netrin-1 Attracts Axons through FAK-Dependent Mechanotransduction

(2012) S. W. Moore et al.   JOURNAL OF NEUROSCIENCE

Optogenetic investigation of neural circuits underlying brain disease in animal models

(2012) Kay M. Tye et al.   NATURE REVIEWS NEUROSCIENCE

UNC-6/netrin and its receptors UNC-5 and UNC-40/DCC modulate growth cone protrusion in vivo in C. elegans

(2011) A. D. Norris et al.   DEVELOPMENT

Light-based feedback for controlling intracellular signaling dynamics

(2011) Jared E Toettcher et al.   NATURE METHODS

Rapid blue-light–mediated induction of protein interactions in living cells

(2010) Matthew J Kennedy et al.   NATURE METHODS

Asymmetric Clathrin-Mediated Endocytosis Drives Repulsive Growth Cone Guidance

(2010) Takuro Tojima et al.   NEURON

The Nitric Oxide-cGMP Pathway Controls the Directional Polarity of Growth Cone Guidance via Modulating Cytosolic Ca2+ Signals

(2009) T. Tojima et al.   JOURNAL OF NEUROSCIENCE

Temporally precise in vivo control of intracellular signalling

(2009) Raag D. Airan et al.   NATURE

A genetically encoded photoactivatable Rac controls the motility of living cells

(2009) Yi I. Wu et al.   NATURE

Formation of Nuclear Bodies of Arabidopsis CRY2 in Response to Blue Light Is Associated with Its Blue Light-Dependent Degradation

(2009) X. Yu et al.   PLANT CELL

Photoexcited CRY2 Interacts with CIB1 to Regulate Transcription and Floral Initiation in Arabidopsis

(2008) H. Liu et al.   SCIENCE