Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death

The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein

(2015) Alessia Franceschini et al.   FASEB JOURNAL

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Luteoloside Suppresses Proliferation and Metastasis of Hepatocellular Carcinoma Cells by Inhibition of NLRP3 Inflammasome

(2014) Shao-hua Fan et al.   PLoS One

Deregulation of the NLRP3 inflammasome in hepatic parenchymal cells during liver cancer progression

(2013) Qing Wei et al.   LABORATORY INVESTIGATION

Expression of P2X7 Receptor Increases In Vivo Tumor Growth

(2012) E. Adinolfi et al.   CANCER RESEARCH

Purines, Purinergic Receptors, and Cancer

(2012) F. Di Virgilio   CANCER RESEARCH

NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling

(2012) Irving C. Allen et al.   IMMUNITY

Microglia Proliferation Is Controlled by P2X7 Receptors in a Pannexin-1-Independent Manner during Early Embryonic Spinal Cord Invasion

(2012) C. Rigato et al.   JOURNAL OF NEUROSCIENCE

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

(2010) Md. Hasan Zaki et al.   IMMUNITY

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

(2010) Irving C. Allen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PML Regulates Apoptosis at Endoplasmic Reticulum by Modulating Calcium Release

(2010) C. Giorgi et al.   SCIENCE

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Expression of the P2X7Receptor Increases the Ca2+Content of the Endoplasmic Reticulum, Activates NFATc1, and Protects from Apoptosis

(2009) Elena Adinolfi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β

(2009) Miyako Okamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Microglia by Amyloid   Requires P2X7 Receptor Expression

(2009) J. M. Sanz et al.   JOURNAL OF IMMUNOLOGY

The Human Cathelicidin LL-37 Modulates the Activities of the P2X7Receptor in a Structure-dependent Manner

(2008) Linda Tomasinsig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular diagnostics in chronic lymphocytic leukemia – Pathogenetic and clinical implications

(2008) Thorsten Zenz et al.   LEUKEMIA & LYMPHOMA