MicroRNA-146a suppresses ROCK1 allowing hyperphosphorylation of tau in Alzheimer’s disease

Serum MicroRNA Profiles Serve as Novel Biomarkers for the Diagnosis of Alzheimer’s Disease

(2015) Hui Dong et al.   DISEASE MARKERS

S6 kinase phosphorylated at T229 is involved in tau and actin pathologies in Alzheimer's disease

(2015) Yuma Sonoda et al.   NEUROPATHOLOGY

Hsa-miR-146a-5p modulates androgen-independent prostate cancer cells apoptosis by targeting ROCK1

(2015) Bin Xu et al.   PROSTATE

MicroRNA Profiling of CSF Reveals Potential Biomarkers to Detect Alzheimer`s Disease

(2015) Johannes Denk et al.   PLoS One

Transport and diffusion of Tau protein in neurons

(2014) Tim Scholz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Microtubule-associated protein tau as a therapeutic target in Alzheimer's disease

(2014) Khalid Iqbal et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

MicroRNA-146a: A Dominant, Negative Regulator of the Innate Immune Response

(2014) Reuben Saba et al.   Frontiers in Immunology

Identification of active transcription factor and miRNA regulatory pathways in Alzheimer’s disease

(2013) Wei Jiang et al.   BIOINFORMATICS

Alteration of the microRNA network during the progression of Alzheimer's disease

(2013) Pierre Lau et al.   EMBO Molecular Medicine

Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission

(2013) Nguyen-Vi Mohamed et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Prostate-derived Sterile 20-like Kinases (PSKs/TAOKs) Phosphorylate Tau Protein and Are Activated in Tangle-bearing Neurons in Alzheimer Disease

(2013) Ignatius A. Tavares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid

(2013) Mareike Müller et al.   NEUROBIOLOGY OF AGING

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

(2012) Bradley T. Hyman et al.   Alzheimers & Dementia

Amyloid-β–Associated Clinical Decline Occurs Only in the Presence of Elevated P-tau

(2012) Rahul S. Desikan et al.   ARCHIVES OF NEUROLOGY

Brain-penetrant microtubule-stabilizing compounds as potential therapeutic agents for tauopathies: Figure 1

(2012) Kurt R. Brunden et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation

(2012) Kevin Vo et al.   Molecular Cancer

Spreading of Alzheimer’s disease inflammatory signaling through soluble micro-RNA

(2012) Walter J. Lukiw et al.   NEUROREPORT

Early Mechanisms of Pathobiology Are Revealed by Transcriptional Temporal Dynamics in Hippocampal CA1 Neurons of Prion Infected Mice

(2012) Anna Majer et al.   PLoS Pathogens

MicroRNAs in Common Human Diseases

(2012) Yu Li et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Advances in the Pathogenesis of Alzheimer’s Disease: Focusing on Tau-Mediated Neurodegeneration

(2012) Yale Duan et al.   Translational Neurodegeneration

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Amyloid-β associated volume loss occurs only in the presence of phospho-tau

(2011) Rahul S. Desikan et al.   ANNALS OF NEUROLOGY

Upregulation of Micro RNA-146a (miRNA-146a), A Marker for Inflammatory Neurodegeneration, in Sporadic Creutzfeldt–Jakob Disease (sCJD) and Gerstmann–Straussler–Scheinker (GSS) Syndrome

(2011) W. J. Lukiw et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Tau Mediated Neurodegeneration: An Insight into Alzheimer’s Disease Pathology

(2011) M. Obulesu et al.   NEUROCHEMICAL RESEARCH

Accumulation of tumor-suppressor PTEN in Alzheimer neurofibrillary tangles

(2010) Yuma Sonoda et al.   NEUROSCIENCE LETTERS

ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability

(2009) S. Vemula et al.   BLOOD

Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex

(2009) Prerna Sethi et al.   NEUROSCIENCE LETTERS

An NF-κB-sensitive Micro RNA-146a-mediated Inflammatory Circuit in Alzheimer Disease and in Stressed Human Brain Cells

(2008) Walter J. Lukiw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Loss of mir-146a function in hormone-refractory prostate cancer

(2008) S.-L. Lin et al.   RNA