Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities

Macrophages and Therapeutic Resistance in Cancer

(2015) Brian Ruffell et al.   CANCER CELL

Contribution of the immune system to bystander and non-targeted effects of ionizing radiation

(2015) Franz Rödel et al.   CANCER LETTERS

TNF Induction of NF-κB RelB Enhances RANKL-Induced Osteoclastogenesis by Promoting Inflammatory Macrophage Differentiation but also Limits It through Suppression of NFATc1 Expression

(2015) Zhijun Zhao et al.   PLoS One

Myeloid-Derived Cells in Tumors: Effects of Radiation

(2015) Ralph E. Vatner et al.   SEMINARS IN RADIATION ONCOLOGY

Low and moderate doses of ionizing radiation up to 2 Gy modulate transmigration and chemotaxis of activated macrophages, provoke an anti-inflammatory cytokine milieu, but do not impact upon viability and phagocytic function

(2014) R. Wunderlich et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Immune cells: plastic players along colorectal cancer progression

(2014) Giuseppe Di Caro et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

“Of Mice and Men”: Arginine Metabolism in Macrophages

(2014) Anita C. Thomas et al.   Frontiers in Immunology

Radiotherapy and the Tumor Stroma: The Importance of Dose and Fractionation

(2014) Turid Hellevik et al.   Frontiers in Oncology

CSF1R Signaling Blockade Stanches Tumor-Infiltrating Myeloid Cells and Improves the Efficacy of Radiotherapy in Prostate Cancer

(2013) J. Xu et al.   CANCER RESEARCH

Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin

(2013) Marie Jaguin et al.   CELLULAR IMMUNOLOGY

Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers

(2013) Rakesh K. Jain   JOURNAL OF CLINICAL ONCOLOGY

Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y1086, c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity

(2013) A P Cardoso et al.   ONCOGENE

Trial Watch

(2013) Erika Vacchelli et al.   OncoImmunology

Reduced secretion of the inflammatory cytokine IL-1β by stimulated peritoneal macrophages of radiosensitive Balb/c mice after exposure to 0.5 or 0.7Gy of ionizing radiation

(2012) Birgit Frischholz et al.   AUTOIMMUNITY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Immunomodulatory Properties and Molecular Effects in Inflammatory Diseases of Low-Dose X-Irradiation

(2012) Franz Rödel et al.   Frontiers in Oncology

Dying cell clearance and its impact on the outcome of tumor radiotherapy

(2012) Kirsten Lauber et al.   Frontiers in Oncology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

(2011) Ganta Chaitanya et al.   Cell Communication and Signaling

Recruitment of Myeloid but not Endothelial Precursor Cells Facilitates Tumor Regrowth after Local Irradiation

(2010) S. V. Kozin et al.   CANCER RESEARCH

The biology of myeloid-derived suppressor cells: The blessing and the curse of morphological and functional heterogeneity

(2010) Je-In Youn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Tumor-Immune Microenvironment and Response to Radiation Therapy

(2010) Stephen L. Shiao et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

Radiation-induced cell death mechanisms

(2010) David Eriksson et al.   TUMOR BIOLOGY

Hematopoietic stem cell: self-renewal versus differentiation

(2010) Jun Seita et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Regulation of macrophage function in tumors: the multifaceted role of NF- B

(2009) T. Hagemann et al.   BLOOD

Differential Effects of Irradiation with Carbon Ions and X-Rays on Macrophage Function

(2009) Sandro CONRAD et al.   JOURNAL OF RADIATION RESEARCH

0.5 Gy Gamma Radiation Suppresses Production of TNF-α through Up-regulation of MKP-1 in Mouse Macrophage RAW264.7 Cells

(2009) Mitsutoshi Tsukimoto et al.   RADIATION RESEARCH

Overview of Radiosensitivity of Human Tumor Cells to Low-Dose-Rate Irradiation

(2008) Jerry R. Williams et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS