Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm’s canal endothelial cells

The Effect of AMA0428, a Novel and Potent ROCK Inhibitor, in a Model of Neovascular Age-Related Macular Degeneration

(2015) K. Hollanders et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

ROCK-Isoform-Specific Polarization of Macrophages Associated with Age-Related Macular Degeneration

(2015) Souska Zandi et al.   Cell Reports

Intra-ocular pressure-lowering effects of a Rho kinase inhibitor, ripasudil (K-115), over 24 hours in primary open-angle glaucoma and ocular hypertension: a randomized, open-label, crossover study

(2014) Hidenobu Tanihara et al.   ACTA OPHTHALMOLOGICA

Effects of K-115, a Rho-Kinase Inhibitor, on Aqueous Humor Dynamics in Rabbits

(2014) Tomoyuki Isobe et al.   CURRENT EYE RESEARCH

Ripasudil: First Global Approval

(2014) Karly P. Garnock-Jones   DRUGS

Phase 2 Randomized Clinical Study of a Rho Kinase Inhibitor, K-115, in Primary Open-Angle Glaucoma and Ocular Hypertension

(2013) Hidenobu Tanihara et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Phase 1 Clinical Trials of a Selective Rho Kinase Inhibitor, K-115

(2013) Hidenobu Tanihara   JAMA Ophthalmology

The New Therapeutic Concept of Using a Rho Kinase Inhibitor for the Treatment of Corneal Endothelial Dysfunction

(2011) Naoki Okumura et al.   CORNEA

Rho Kinase Inhibition by Fasudil Ameliorates Diabetes-Induced Microvascular Damage

(2008) R. Arita et al.   DIABETES

Extracellular matrix in the trabecular meshwork

(2008) Ted S. Acott et al.   EXPERIMENTAL EYE RESEARCH

The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes

(2007) Zhaozeng Lu et al.   EXPERIMENTAL EYE RESEARCH