A Novel PET Imaging Probe for the Detection and Monitoring of Translocator Protein 18 kDa Expression in Pathological Disorders

Radiosynthesis and in vivo evaluation of two imidazopyridineacetamides, [11C]CB184 and [11C]CB190, as a PET tracer for 18 kDa translocator protein: direct comparison with [11C](R)-PK11195

(2015) Kentaro Hatano et al.   ANNALS OF NUCLEAR MEDICINE

Development of additive [ 11 C]CO 2 target system in the KOTRON-13 cyclotron and its application for [ 11 C]radiopharmaceutical production

(2015) Byung Seok Moon et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS

Structure and activity of tryptophan-rich TSPO proteins

(2015) Y. Guo et al.   SCIENCE

Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism

(2015) F. Li et al.   SCIENCE

[18F]Fluoromethyl-PBR28 as a Potential Radiotracer for TSPO: Preclinical Comparison with [11C]PBR28 in a Rat Model of Neuroinflammation

(2014) Byung Seok Moon et al.   BIOCONJUGATE CHEMISTRY

Comparison of in vivo binding properties of the 18-kDa translocator protein (TSPO) ligands [18F]PBR102 and [18F]PBR111 in a model of excitotoxin-induced neuroinflammation

(2014) P. D. Callaghan et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Structure of the Mitochondrial Translocator Protein in Complex with a Diagnostic Ligand

(2014)  ukasz Jaremko et al.   SCIENCE

Longitudinal PET Imaging of Muscular Inflammation Using 18F-DPA-714 and 18F-Alfatide II and Differentiation with Tumors

(2014) Chenxi Wu et al.   Theranostics

In vitro targeting and imaging the translocator protein TSPO 18-kDa through G(4)-PAMAM–FITC labeled dendrimer

(2013) Nunzio Denora et al.   JOURNAL OF CONTROLLED RELEASE

PET imaging of brain inflammation during early epileptogenesis in a rat model of temporal lobe epilepsy

(2013) Stefanie Dedeurwaerdere et al.   EJNMMI Research

New Fluorescent Probes Targeting the Mitochondrial-Located Translocator Protein 18 kDa (TSPO) as Activated Microglia Imaging Agents

(2011) Nunzio Denora et al.   PHARMACEUTICAL RESEARCH

PET tracers for the peripheral benzodiazepine receptor and uses thereof

(2010) Pernilla J. Schweitzer et al.   DRUG DISCOVERY TODAY

Translocator Protein (TSPO) Ligand−Ara-C (Cytarabine) Conjugates as a Strategy To Deliver Antineoplastic Drugs and To Enhance Drug Clinical Potential

(2010) Nunzio Denora et al.   MOLECULAR PHARMACEUTICS

Peripheral Benzodiazepine Receptor ligand–PLGA polymer conjugates potentially useful as delivery systems of apoptotic agents

(2009) Valentino Laquintana et al.   JOURNAL OF CONTROLLED RELEASE

Comparison of [11C]-(R)-PK 11195 and [11C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker

(2009) William C. Kreisl et al.   NEUROIMAGE

Synthesis, fluorine-18 radiolabeling, and in vitro characterization of 1-iodophenyl-N-methyl-N-fluoroalkyl-3-isoquinoline carboxamide derivatives as potential PET radioligands for imaging peripheral benzodiazepine receptor

(2008) Weiping Yu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers

(2008) Fabien Chauveau et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

2-Phenyl-imidazo[1,2-a]pyridine Compounds Containing Hydrophilic Groups as Potent and Selective Ligands for Peripheral Benzodiazepine Receptors: Synthesis, Binding Affinity and Electrophysiological Studies

(2008) Nunzio Denora et al.   JOURNAL OF MEDICINAL CHEMISTRY

Radiosynthesis and in vivo evaluation of N-[11C]methylated imidazopyridineacetamides as PET tracers for peripheral benzodiazepine receptors

(2008) Katsuhiko Sekimata et al.   NUCLEAR MEDICINE AND BIOLOGY

Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors

(2007) Masao Imaizumi et al.   NEUROIMAGE