Alp7/TACC-Alp14/TOG generates long-lived, fast-growing MTs by an unconventional mechanism

Targeting Alp7/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast

(2014) Ngang Heok Tang et al.   FEBS LETTERS

Stu2, the Budding Yeast XMAP215/Dis1 Homolog, Promotes Assembly of Yeast Microtubules by Increasing Growth Rate and Decreasing Catastrophe Frequency

(2014) Marija Podolski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The contribution of αβ-tubulin curvature to microtubule dynamics

(2014) Gary J. Brouhard et al.   JOURNAL OF CELL BIOLOGY

Alp7/TACC recruits kinesin-8-PP1 to the Ndc80 kinetochore protein for timely mitotic progression and chromosome movement

(2014) N. H. Tang et al.   JOURNAL OF CELL SCIENCE

The XMAP215 family drives microtubule polymerization using a structurally diverse TOG array

(2014) Jaime C. Fox et al.   MOLECULAR BIOLOGY OF THE CELL

CDK-dependent phosphorylation of Alp7–Alp14 (TACC–TOG) promotes its nuclear accumulation and spindle microtubule assembly

(2014) Naoyuki Okada et al.   MOLECULAR BIOLOGY OF THE CELL

A tethered delivery mechanism explains the catalytic action of a microtubule polymerase

(2014) Pelin Ayaz et al.   eLife

Microtubule dynamic instability: A new model with coupled GTP hydrolysis and multistep catastrophe

(2013) Hugo Bowne-Anderson et al.   BIOESSAYS

The internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment

(2013) Ngang Heok Tang et al.   MOLECULAR BIOLOGY OF THE CELL

Microtubules and Alp7–Alp14 (TACC–TOG) reposition chromosomes before meiotic segregation

(2013) Yasutaka Kakui et al.   NATURE CELL BIOLOGY

XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules

(2013) Simone B. Reber et al.   NATURE CELL BIOLOGY

Fission yeast Alp14 is a dose-dependent plus end–tracking microtubule polymerase

(2012) Jawdat Al-Bassam et al.   MOLECULAR BIOLOGY OF THE CELL

S. pombe Kinesins-8 Promote Both Nucleation and Catastrophe of Microtubules

(2012) Muriel Erent et al.   PLoS One

A TOG:  -tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase

(2012) P. Ayaz et al.   SCIENCE

Rapid Microtubule Self-Assembly Kinetics

(2011) Melissa K. Gardner et al.   CELL

XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region

(2011) P. O. Widlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microtubule tip-interacting proteins: a view from both ends

(2010) Kai Jiang et al.   CURRENT OPINION IN CELL BIOLOGY

The role of TOG domains in microtubule plus end dynamics

(2009) Kevin C. Slep   BIOCHEMICAL SOCIETY TRANSACTIONS

The Fission Yeast TACC Protein Mia1p Stabilizes Microtubule Arrays by Length-Independent Crosslinking

(2009) Rahul Thadani et al.   CURRENT BIOLOGY

Nucleocytoplasmic transport of Alp7/TACC organizes spatiotemporal microtubule formation in fission yeast

(2009) Masamitsu Sato et al.   EMBO REPORTS

The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism

(2009) Marcus Braun et al.   NATURE CELL BIOLOGY

Nucleocytoplasmic Shuttling of the TACC Protein Mia1p/Alp7p Is Required for Remodeling of Microtubule Arrays during the Cell Cycle

(2009) Yuen Chyao Ling et al.   PLoS One

XMAP215 Is a Processive Microtubule Polymerase

(2008) Gary J. Brouhard et al.   CELL