CRISPR/Cas9-mediated GJA8 knockout in rabbits recapitulates human congenital cataracts
Published 2016 View Full Article
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Title
CRISPR/Cas9-mediated GJA8 knockout in rabbits recapitulates human congenital cataracts
Authors
Keywords
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Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-02-25
DOI
10.1038/srep22024
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Note: Only part of the references are listed.- A novel Cx50 (GJA8) p.H277Y mutation associated with autosomal dominant congenital cataract identified with targeted next-generation sequencing
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- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
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- A novel mutation in CRYBB1 associated with congenital cataract-microcornea syndrome: the p.Ser129Arg mutation destabilizes the βB1/βA3-crystallin heteromer but not the βB1-crystallin homomer
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- A Novel Mutation in the Connexin 50 Gene (GJA8) Associated with Autosomal Dominant Congenital Nuclear Cataract in a Chinese Family
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- The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
- (2010) Josiane E. Garneau et al. NATURE
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