Article
Physiology
Jorge M. C. Ferreira, Robert Huhle, Sabine Mueller, Christian Schnabel, Mirko Mehner, Thea Koch, Marcelo Gama de Abreu
Summary: The study found that static stretch increases the pro-inflammatory response of rat type 2 alveolar epithelial cells to dynamic stretch, particularly in cells stimulated with LPS. This suggests that static stretch may have an impact on lung inflammation response during mechanical ventilation.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Physiology
Yali Zhao, Shankar Iyer, Maryam Tavanaei, Nicole T. Nguyen, Andrew Lin, Thao P. Nguyen
Summary: This study demonstrates that myofibroblasts and other noncardiomyocytes can induce both structural and electrical remodeling in the heart, leading to arrhythmias, particularly in the presence of oxidative stress. Understanding the arrhythmogenicity of synergistic electrical remodeling by oxidative stress and noncardiomyocytes may help develop safe antiarrhythmic strategies for cardiac regenerative therapies.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Cell & Tissue Engineering
Kathryn Ufford, Sabrina Friedline, Zhaowen Tong, Vi T. Tang, Amani S. Dobbs, Yao-Chang Tsan, Stephanie L. Bielas, Allen P. Liu, Adam S. Helms
Summary: This study aims to investigate the impact of myofibrillar structure on contractile function in iPSC-CMs. The results show that myofibrillar abundance is widely variable among iPSC-CMs and strongly correlates with contractile function. Controlling for myofibrillar structure can reduce false-positive findings, improve sensitivity for pharmacologic testing and disease modeling.
Article
Management
Will Ma, David Simchi-Levi, Jinglong Zhao
Summary: This study investigates the efficacy of static control policies in revenue management problems for a large consumer packaged goods company. The results show that simple static policies can approximate the optimal solution, especially with large initial inventories. The adaptation of prophet inequalities from optimal stopping theory to pricing and assortment problems is effective in addressing dynamic demand and allocation challenges.
MANAGEMENT SCIENCE
(2021)
Article
Engineering, Chemical
Yesenia Saavedra Moreno, Ghislain Bournival, Seher Ata
Summary: This study provides a detailed understanding of the relationship between frother type and foam stability under dynamic and static conditions. It was found that the foaminess of aliphatic alcohols increased with the number of hydrocarbon groups, while the stability of polypropylene glycols varied with the number of propylene oxide groups. Interestingly, an increase in propylene oxide groups led to higher foaminess, foam half-life and decay rate coefficient for propylene glycol methyl ethers.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Materials Science, Ceramics
A. Yu. Potanin, A. N. Astapov, Yu. S. Pogozhev, S. I. Rupasov, N. V. Shvyndina, V. V. Klechkovskaya, E. A. Levashov, I. A. Timofeev, A. N. Timofeev
Summary: The kinetics and mechanism of oxidation of ceramics based on HfB2 and SiC were investigated. The ceramics showed high structural and chemical homogeneity, with varying properties depending on the ratio between the main components.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2021)
Article
Engineering, Biomedical
Bobby Carroll, Minh-Tri Ho Thanh, Alison E. Patteson
Summary: The mechanical properties of tissues are crucial for tissue development and maintenance. By studying the mechanical behavior of fibrous networks embedded with stiff beads, it is found that the presence of beads enhances the mechanical performance of the network under compression, possibly due to the hindrance of network relaxation.
ACTA BIOMATERIALIA
(2023)
Article
Mechanics
Michal Rajnak, Bystrik Dolnik, Patrik Hodermarsky, Katarina Paulovicova, Roman Cimbala, Milan Timko, Peter Kopcansky
Summary: Magnetic nanoparticles in a non-polar ferrofluid can reassemble in external electric fields, influencing the magnetic response of ferrofluids. Under a static electric field, the magnetic susceptibility of a ferrofluid based on insulating oil and iron oxide nanoparticles decreases with increasing voltage, partially due to temperature increase. Other mechanisms such as nanoparticle trapping and aggregation induced by the electric field also contribute to the susceptibility drop.
Article
Chemistry, Physical
Chaosheng Yuan, Xin Zhang, Leijun Zhou, Haining Li, Shiquan Feng, Kun Yang, Xiang Zhu
Summary: Carbon tetrachloride undergoes multiple phase transitions under static and dynamic compression, including liquid-liquid phase transition and solidification. The phase transition behavior is influenced by pressure-induced supercooling and fast compression rate.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Biochemistry & Molecular Biology
Jessica Selig, Joana Boulgaropoulos, Naima Niazy, D. Margriet Ouwens, Karlheinz Preuss, Patrick Horn, Ralf Westenfeld, Artur Lichtenberg, Payam Akhyari, Mareike Barth
Summary: The study analyzed the influence of hyperinsulinemia and hyperglycemia on degenerative processes in valvular tissue, and found that dynamic cultivation resulted in significantly stronger fibrosis in AV tissue compared to static cultivation. Hyperinsulinemia and hyperglycemia altered the expression of key differentiation markers and proteoglycans in a manner dependent on the environment, and affected insulin-signaling pathways.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Engineering, Geological
Junwen Zhang, Wenbing Fan, Yang Yang, Yang Zhang, Xukai Dong, Yulong Xing, Weigang Zeng, Kailun Fang
Summary: Impact disturbance and bedding angle significantly affect the mechanical response of sandstone under prestressed loading. A combined 1D static and dynamic loading test system is employed to investigate the compression behavior of sandstone at different bedding angles. The results show that strain rebound easily occurs in high-strength sandstone under low impact pressure, and the peak strength of sandstone is positively correlated with the impact pressure. Additionally, the impact pressure influences the crack growth rate of sandstone.
SOIL DYNAMICS AND EARTHQUAKE ENGINEERING
(2023)
Article
Materials Science, Multidisciplinary
Hongliang Su, Bingxin Xie, Xiangnan Men, Tao Deng, Yingqiang He, Hongtao Zhang, Liang Huang, Jianjun Li
Summary: It has been confirmed that electromagnetic forming can significantly improve the formability of lightweight but difficult-to-form metals, but the underlying physical mechanism is still debated. This study applied quasi-static, mechanical dynamic, and electromagnetic dynamic loading to 2219 aluminum alloy to examine the specific influences of strain, strain rate, inertial effect, pulsed magnetic field, and eddy current on microstructure evolution. The results showed that mechanical dynamic deformation increased the uniaxial tensile limit strain by 26% compared to quasi-static deformation, while electromagnetic dynamic deformation increased it by 41%. Inertial effect during high-speed deformation dispersed defect development and local instabilities, thus enhancing formability. Additionally, as strain increased, the material's microstructure evolved through various mechanisms, including dislocation multiplication, grain refinement, increase in low angle grain boundary, and formation of dislocation cells.
MATERIALS CHARACTERIZATION
(2023)
Article
Materials Science, Multidisciplinary
Jialei Dai, Jun Yuan, Zixuan Yang, Chaoqun Zhang, Hao Zhang, Shuqin Yu
Summary: This study investigates the deformation and fracture behavior of Quenching and Partitioning (Q&P) steel at different strain rates. The results show that the strength and plasticity of Q&P steel are significantly affected by the strain rate. The elongation of Q&P steel initially decreases and then increases with increasing strain rate, while the dimples become smaller and flatter. At high strain rates, the dislocation density increases, inhibiting the generation of large deformation. The fracture morphology exhibits partial brittle fracture characteristics, with a significant decrease in local plastic strain.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Spectroscopy
Usha Rao, S. Chaurasia, Ajay K. Mishra, John Pasley
Summary: The study investigates phase transitions in liquid benzene under laser shocked conditions using high-resolution time-resolved Raman spectroscopy. Phase transitions from liquid to solid benzene at different pressures were observed, as well as the effect of shock waves on benzene compared to isothermal compression. High-resolution spectra helped determine the pressure gradient effect and spatial profiles of shock wave propagation in benzene, leading to the observation of multiple Raman modes and new Raman signals attributed to phase transitions under dynamic compression.
JOURNAL OF RAMAN SPECTROSCOPY
(2021)
Article
Agronomy
Shengnan Ge, Debin Liu, Min Chu, Xinyu Liu, Yulei Wei, Xinyang Che, Lei Zhu, Lin He, Jingyu Xu
Summary: This study investigated the changes in membrane lipids in sorghum leaves under salt stress. Salt stress increased the content of phospholipids in sorghum leaves while decreasing the proportion of MGDG and PG. The adjustment of glycerolipid pathways between the cytosolic and plastidic compartments was triggered by salt stress.
Editorial Material
Anatomy & Morphology
Raymond B. Runyan, Pierre Savagner
DEVELOPMENTAL DYNAMICS
(2018)
Article
Toxicology
Alondra P. Harris, Kareem A. Ismail, Martha Nunez, Ira Martopullo, Alejandro Lencinas, Ornella I. Selmin, Raymond B. Runyan
TOXICOLOGY LETTERS
(2018)
Article
Engineering, Biomedical
Ryan J. Avery, Soojie K. Yu, Gopi Cherukuri, Ray B. Runyan, John Konhilas, Zain I. Khalpey
Article
Surgery
Valentine N. Nfonsam, Landry E. Nfonsam, Debbie Chen, Pamela N. Omesiete, Alejandro Cruz, Raymond B. Runyan, Jana Jandova
JOURNAL OF SURGICAL RESEARCH
(2019)
Article
Biochemical Research Methods
Cai Yuan, Zhonghai Wang, Thomas K. Borg, Tong Ye, Catalin Baicu, Amy Bradshaw, Michael Zile, Raymond B. Runyan, Yonghong Shao, Bruce Z. Gao
BIOMEDICAL OPTICS EXPRESS
(2019)
Letter
Developmental Biology
Raymond B. Runyan, Ornella I. Selmin, Susan M. Smith, Jennifer L. Freeman
BIRTH DEFECTS RESEARCH
(2019)
Article
Biophysics
Cai Yuan, Xiaolei Zhao, Zhonghai Wang, Thomas K. Borg, Tong Ye, Zain Khalpey, Raymond B. Runyan, Yonghong Shao, Bruce Z. Gao
BIOPHYSICAL JOURNAL
(2020)
Article
Cardiac & Cardiovascular Systems
Mei Methawasin, Joshua Strom, Tomasz Borkowski, Zaynab Hourani, Ray Runyan, John E. Smith, Henk Granzier
CIRCULATION-HEART FAILURE
(2020)
Review
Cell Biology
Jing Yang, Parker Antin, Geert Berx, Cedric Blanpain, Thomas Brabletz, Marianne Bronner, Kyra Campbell, Amparo Cano, Jordi Casanova, Gerhard Christofori, Shoukat Dedhar, Rik Derynck, Heide L. Ford, Jonas Fuxe, Antonio Garcia de Herreros, Gregory J. Goodall, Anna-Katerina Hadjantonakis, Ruby J. Y. Huang, Chaya Kalcheim, Raghu Kalluri, Yibin Kang, Yeesim Khew-Goodall, Herbert Levine, Jinsong Liu, Gregory D. Longmore, Sendurai A. Mani, Joan Massague, Roberto Mayor, David McClay, Keith E. Mostov, Donald F. Newgreen, M. Angela Nieto, Alain Puisieux, Raymond Runyan, Pierre Savagner, Ben Stanger, Marc P. Stemmler, Yoshiko Takahashi, Masatoshi Takeichi, Eric Theveneau, Jean Paul Thiery, Erik W. Thompson, Robert A. Weinberg, Elizabeth D. Williams, Jianhua Xing, Binhua P. Zhou, Guojun Sheng
NATURE REVIEWS MOLECULAR CELL BIOLOGY
(2020)
Article
Surgery
Emily Wusterbarth, Yuliang Chen, Hunter Jecius, Erika Krall, Raymond B. Runyan, Ritu Pandey, Valentine Nfonsam
Summary: COMP is a potential molecular biomarker for colon cancer, with significant expression differences across different disease stages and subtypes. COMP appears to be a stronger molecular marker compared to CEACAM5 across stages and subtypes. CMS4 is associated with high COMP expression, and higher COMP levels are correlated with poorer disease outcomes.
JOURNAL OF SURGICAL RESEARCH
(2022)
Meeting Abstract
Gastroenterology & Hepatology
D. Chen, L. Nfonsam, A. Cruz, A. N. Ewongwo, O. P. Mogor, R. Runyan, V. N. Nfonsam
DISEASES OF THE COLON & RECTUM
(2018)
Meeting Abstract
Gastroenterology & Hepatology
L. Nfonsam, D. Chen, O. P. Mogor, A. Cruz, A. N. Ewongwo, R. Runyan, V. N. Nfonsam
DISEASES OF THE COLON & RECTUM
(2018)
Meeting Abstract
Gastroenterology & Hepatology
V. N. Nfonsam, D. Chen, A. Cruz, L. Nfonsam, A. N. Ewongwo, O. P. Mogor, R. Runyan
DISEASES OF THE COLON & RECTUM
(2018)
Article
Anatomy & Morphology
Andre L. P. Tavares, Jessie A. Brown, Emily C. Ulrich, Katerina Dvorak, Raymond B. Runyan
DEVELOPMENTAL DYNAMICS
(2018)
Article
Chemistry, Analytical
Sheri Chen, Alejandro Lencinas, Martha Nunez, Ornella I. Selmin, Raymond B. Runyan
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2020)