Article
Oncology
Katsuo Usuda, Shun Iwai, Aika Yamagata, Yoshihito Iijima, Nozomu Motono, Munetaka Matoba, Mariko Doai, Keiya Hirata, Hidetaka Uramoto
Summary: This study aimed to differentiate lung cancer from pulmonary abscesses and mycobacterial infections using ADC histogram. Results showed significant differences in ADC values between lung cancer and PAMI, suggesting the potential of ADC histogram as a valuable tool for differentiation.
Article
Radiology, Nuclear Medicine & Medical Imaging
ChunMei Yang, Xin Quan, XinQiao Huang, ZhuoYue Tang, Jian Shu
Summary: The ADC value might be a potential imaging biomarker for predicting the malignancy of extrahepatic cholangiocarcinoma (ECC) and is significantly correlated with pathological differentiation degree. In addition, ADC value is negatively correlated with microvascular density and lesion size, but not with patient age.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xue Li, Hong Wang, Jiayin Gao, Lei Jiang, Min Chen
Summary: Quantitative ADC metrics generally outperformed BI-RADS parameters in distinguishing MRI-only suspicious lesions, with ADCmean being the best ADC parameter for differentiating MRI-only lesions.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Oncology
Li-Ting Liu, Shan-Shan Guo, Hui Li, Chao Lin, Rui Sun, Qiu-Yan Chen, Yu-Jing Liang, Qing-Nan Tang, Xue-Song Sun, Lin-Quan Tang, Chuan-Miao Xie, Hai-Qiang Mai
Summary: The percentage change in ADC post-IC is indicative of treatment response and clinical outcome. Delta ADC% and plasma EBV DNA-based response phenotypes may provide potential utility for early termination of treatment and allow guiding risk-adapted therapeutic strategies for LA-NPC.
Article
Multidisciplinary Sciences
Hyeong-Cheol Oh, Chang-Ki Hong, Kyu-Sung Lee, Yoon Jin Cha, Sung Jun Ahn, Sang Hyun Suh, Hun Ho Park
Summary: Clival chordoma is a rare disease with high recurrence rates. This study found that preoperative ADC values can be useful in predicting tumor progression and recurrence in patients with clival chordoma. Patients with ADC values below specific cutoff points are more likely to exhibit aggressive tumor features.
SCIENTIFIC REPORTS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Huali Ma, Yinyi Qiu, Haojiang Li, Fei Xie, Guangying Ruan, Lizhi Liu, Chunyan Cui, Annan Dong
Summary: Nodal matting was found to be an independent prognostic factor for distant metastasis-free survival in NPC patients, with potential to identify high-risk patients. The nomogram including nodal matting showed higher predictive accuracy compared to the nomogram without it.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Oncology
Jijun Zhang, Xiaoya Luo, Qitao Huang, Yuhua Huang
Summary: Nasopharyngeal carcinoma in children and adolescents is rare, with most cases staged as Stage IVa disease. The majority of patients tested positive for EBV antibodies, with a significant difference in survival rates observed in patients with high plasma EBV DNA and positive serum EBV antibodies.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Oncology
Zhaohui Liu, Lin Zhu, Yong Liu, Xiaorong Huang, Chaojun Wang, Yongyang Yu
Summary: This study aimed to investigate the predictive value of apparent diffusion coefficient (ADC) in dynamic enhanced magnetic resonance imaging (MRI) for the efficacy of neoadjuvant chemotherapy in colorectal cancer (CRC) patients. The results showed that ADC was significantly associated with the efficacy of neoadjuvant chemotherapy and could serve as a predictor for both objective response and 5-year survival rate in locally advanced CRC patients.
JOURNAL OF GASTROINTESTINAL ONCOLOGY
(2023)
Article
Clinical Neurology
Jatta Berberat, Ulrich Roelcke, Luca Remonda, Lucia Schwyzer
Summary: A noninvasive method using the apparent diffusion coefficient (ADC) to predict the progress or treatment response of meningiomas was studied. The results showed that ADC values remained stable in conservatively managed meningiomas, while significant changes were observed in meningiomas undergoing radiosurgery, suggesting the potential of ADC changes as an indicator of treatment response.
ACTA NEUROCHIRURGICA
(2021)
Article
Oncology
Yui Watanabe, Satoshi Nakamura, Yasutaka Ichikawa, Noriko Ii, Tomoko Kawamura, Eiji Kondo, Tomoaki Ikeda, Yoshihito Nomoto, Hajime Sakuma
Summary: This study showed that early changes in tumor ADCs and volume during treatment in cervical cancer patients are associated with better prognosis. %ADC increase and %Volume reduction during treatment provide additional prognostic value for predicting tumor recurrence compared to pre-treatment ADC and tumor volume.
RADIOTHERAPY AND ONCOLOGY
(2021)
Article
Medicine, General & Internal
Sebnem Orguc, Cagdas Riza Acar
Summary: This study compared the roles of MRI scanning and elastography based on ultrasound shear wave measurements in assessing breast masses. The results showed a negative correlation between the ADC values and elasticity of the breast masses. However, both methods were unable to predict the status of prognostic factors and differentiate between molecular subtypes.
Article
Radiology, Nuclear Medicine & Medical Imaging
Hiroyuki Tatekawa, Akifumi Hagiwara, Jingwen Yao, Talia C. Oughourlian, Issei Ueda, Hiroyuki Uetani, Catalina Raymond, Albert Lai, Timothy F. Cloughesy, Phioanh L. Nghiemphu, Linda M. Liau, Whitney B. Pope, Noriko Salamon, Benjamin M. Ellingson
Summary: This study aimed to investigate correlations between F-18-FDOPA uptake and physiologic MRI in gliomas with different molecular subtypes, and evaluate their prognostic values. Results showed significant positive correlations between nSUV and rCBV, as well as negative correlations with ADC for IDHwt and IDHm-noncodel gliomas, while IDHm-codel gliomas demonstrated unique patterns of correlations. Cox regression analysis revealed significant associations between nSUV-rCBV or nSUV-ADC correlations and overall survival only in IDHwt gliomas.
JOURNAL OF NUCLEAR MEDICINE
(2021)
Article
Oncology
Cem Onal, Gurcan Erbay, Ozan Cem Guler, Ezgi Oymak
Summary: The study aims to assess the correlation between initial tumor ADC values and clinicopathological parameters in prostate cancer patients treated with radiotherapy, and analyze the prognostic factors for FFBF and PFS. The results showed that lower ADC values were associated with high-risk characteristics and increased risk of biochemical failure and progression.
RADIOTHERAPY AND ONCOLOGY
(2022)
Article
Oncology
Shao-Bo Liang, Lu-Si Chen, Hai-Yang Chen, Xing-Li Yang, Dong-Hui Wang, Chun-Yan Cui, Chuan-Bo Xie, Li-Zhi Liu, Xiang-Ying Xu
Summary: The study evaluated the impact of prevertebral space involvement (PSI) and tumor extension on prognosis in nasopharyngeal carcinoma patients. Results show that PSI is an independent predictor of poor prognosis, with BPMI patients having lower survival rates than PMI patients, and NPC with PSI should be classified as T4 stage.
RADIOTHERAPY AND ONCOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xianwang Liu, Tao Han, Yuzhu Wang, Hong Liu, Xiaoyu Huang, Junlin Zhou
Summary: ADC histogram analysis can be helpful in differentiating angiomatous meningioma and atypical meningioma. The study found significant correlations between mean ADC, ADC1, ADC10, ADC50 and the Ki-67 proliferation index, with ADC1 demonstrating the best diagnostic performance.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)