Extracellular iron diminishes anticancer effects of vitamin C: An in vitro study

Review of high-dose intravenous vitamin C as an anticancer agent

(2014) Michelle K Wilson et al.   Asia-Pacific Journal of Clinical Oncology

Intracellular ascorbate enhances hypoxia-inducible factor (HIF)-hydroxylase activity and preferentially suppresses the HIF-1 transcriptional response

(2014) Caroline Kuiper et al.   FREE RADICAL BIOLOGY AND MEDICINE

Parenteral Ascorbate As a Cancer Therapeutic: A Reassessment Based on Pharmacokinetics

(2013) Nermi L. Parrow et al.   ANTIOXIDANTS & REDOX SIGNALING

Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial

(2013) J. L. Welsh et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer

(2013) Christopher M. Stephenson et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Manganoporphyrins Increase Ascorbate-Induced Cytotoxicity by Enhancing H2O2 Generation

(2013) M. Rawal et al.   CANCER RESEARCH

The ROS-induced cytotoxicity of ascorbate is attenuated by hypoxia and HIF-1alpha in the NCI60 cancer cell lines

(2013) Tobias Sinnberg et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The role of iron and reactive oxygen species in cell death

(2013) Scott J Dixon et al.   Nature Chemical Biology

High Concentrations of L-Ascorbic Acid Specifically Inhibit the Growth of Human Leukemic Cells via Downregulation of HIF-1α Transcription

(2013) Hiroshi Kawada et al.   PLoS One

Fluctuating vs. Continuous Exposure to H2O2: The Effects on Mitochondrial Membrane Potential, Intracellular Calcium, and NF-κB in Astroglia

(2013) Aleksandar Bajić et al.   PLoS One

A Simple Assay for Measuring Catalase Activity: A Visual Approach

(2013) Tadayuki Iwase et al.   Scientific Reports

Pharmacological concentrations of ascorbate radiosensitize glioblastoma multiforme primary cells by increasing oxidative DNA damage and inhibiting G2/M arrest

(2012) Patries M. Herst et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibitors of hydroperoxide metabolism enhance ascorbate-induced cytotoxicity

(2012) K. E. Olney et al.   FREE RADICAL RESEARCH

Hydrogen Peroxide in Adaptation

(2012) Ivan Spasojević et al.   Oxidative Medicine and Cellular Longevity

Differential oxidative status and immune characterization of the early and advanced stages of human breast cancer

(2011) C. Panis et al.   BREAST CANCER RESEARCH AND TREATMENT

Free radicals and antioxidants at a glance using EPR spectroscopy

(2011) Ivan Spasojević   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Comment on “Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer,” i.e., all we are saying is, give C a chance

(2011) Joseph J. Cullen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hepcidin and Disorders of Iron Metabolism

(2010) Tomas Ganz et al.   Annual Review of Medicine

Metalloporphyrin Synergizes with Ascorbic Acid to Inhibit Cancer Cell Growth Through Fenton Chemistry

(2010) Junqiang Tian et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

H2O2-mediated Cytotoxicity of Pharmacologic Ascorbate Concentrations to Neuroblastoma Cells: Potential Role of Lactate and Ferritin

(2010) Beate Deubzer et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Bioavailability and catalytic properties of copper and iron for Fenton chemistry in human cerebrospinal fluid

(2010) Ivan Spasojević et al.   REDOX REPORT

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

(2009) Douglas B Kell   BMC Medical Genomics

Dietary Intake and Serum Levels of Iron in Relation to Oxidative Stress in Breast Cancer Patients

(2009) Yun-Jung Bae et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Phase I clinical trial of i.v. ascorbic acid in advanced malignancy

(2008) L. J. Hoffer et al.   ANNALS OF ONCOLOGY

Reactive Oxygen Species Regulate Hypoxia-Inducible Factor 1  Differentially in Cancer and Ischemia

(2008) A. A. Qutub et al.   MOLECULAR AND CELLULAR BIOLOGY