Histone deacetylases inhibition by SAHA/Vorinostat normalizes the glioma microenvironment via xCT equilibration

Nrf2 target genes can be controlled by neuronal activity in the absence of Nrf2 and astrocytes

(2014) R. F. Deighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

(2014) Scott J Dixon et al.   eLife

Reprint of: Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs

(2013) Takumi Satoh et al.   FREE RADICAL BIOLOGY AND MEDICINE

The emerging role of the Nrf2-Keap1 signaling pathway in cancer

(2013) M. C. Jaramillo et al.   GENES & DEVELOPMENT

The return of the nucleus: transcriptional and epigenetic control of autophagy

(2013) Jens Füllgrabe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Surgical resection of malignant gliomas—role in optimizing patient outcome

(2013) Ilker Y. Eyüpoglu et al.   Nature Reviews Neurology

Histone acetylation: molecular mnemonics on the chromatin

(2013) Johannes Gräff et al.   NATURE REVIEWS NEUROSCIENCE

Comparative assessment of 5 methods (methylation-specific polymerase chain reaction, methylight, pyrosequencing, methylation-sensitive high-resolution melting, and immunohistochemistry) to analyze O6-methylguanine-DNA-methyltranferase in a series of 100 g

(2012) Véronique Quillien et al.   CANCER

New strategies for targeting the hypoxic tumour microenvironment in breast cancer

(2012) Carol Ward et al.   CANCER TREATMENT REVIEWS

Type-3 metabotropic glutamate receptors regulate chemoresistance in glioma stem cells and their levels are inversely related to survival in patients with malignant gliomas

(2012) C Ciceroni et al.   CELL DEATH AND DIFFERENTIATION

Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage

(2012) Soo Han Bae et al.   Cell Metabolism

Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial

(2012) Wolfgang Wick et al.   LANCET ONCOLOGY

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

(2012) Matthew F. Barber et al.   NATURE

Early prediction of response to Vorinostat in an orthotopic rat glioma model

(2012) Li Wei et al.   NMR IN BIOMEDICINE

Methylation profile of triple-negative breast carcinomas

(2012) M T Branham et al.   Oncogenesis

CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth

(2011) Takatsugu Ishimoto et al.   CANCER CELL

Mutation of ATF4 mediates resistance of neuronal cell lines against oxidative stress by inducing xCT expression

(2011) J Lewerenz et al.   CELL DEATH AND DIFFERENTIATION

Dual neuroprotective pathways of a pro-electrophilic compound via HSF-1-activated heat-shock proteins and Nrf2-activated phase 2 antioxidant response enzymes

(2011) Takumi Satoh et al.   JOURNAL OF NEUROCHEMISTRY

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

(2011) Raffaella Di Micco et al.   NATURE CELL BIOLOGY

Glutamate release by primary brain tumors induces epileptic activity

(2011) Susan C Buckingham et al.   NATURE MEDICINE

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

(2010) E. G. Van Meir et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas

(2010) N E Savaskan et al.   ONCOGENE

Cellular characterization of the peritumoral edema zone in malignant brain tumors

(2009) Tobias Engelhorn et al.   CANCER SCIENCE

The xc−cystine/glutamate antiporter (xCT) as a potential target for therapy of cancer: Yet another cytotoxic anticancer approach?

(2009) Nic E. Savaskan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Histone deacetylases and the immunological network: implications in cancer and inflammation

(2009) A Villagra et al.   ONCOGENE

Small interfering RNA–mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema

(2008) Nicolai E Savaskan et al.   NATURE MEDICINE