Article
Mathematics, Applied
Isaac Harris
Summary: The paper introduces a new regularized factorization method for imaging unknown regions to avoid numerical instabilities, proving efficient and accurate in dense optical tomography.
Article
Mathematics, Applied
Manabu Machida
Summary: This paper presents a method for nonlinear reconstruction using the inverse Rytov series. In diffuse optical tomography, the Rytov approximation is found to provide better reconstructed images compared to the Born approximation. The linearization of inverse problems is an essential part of the Rytov approximation, and it is found that the inverse Rytov series has a recursive structure similar to the inverse Born series.
Article
Computer Science, Artificial Intelligence
Anuj Abhishek, Thilo Strauss, Taufiquar Khan
Summary: Diffuse Optical Tomography (DOT) is a widely used imaging technique with applications in medical imaging. It recovers the optical properties of an object by measuring photon density using laser sources placed on the object's surface. However, the reconstruction of DOT is challenged by the ill-posedness of the inverse problem, resulting in poor image quality. This study presents a Bayesian estimator for the absorption coefficient in a simplified DOT model, demonstrating its convergence and optimality.
SIAM JOURNAL ON IMAGING SCIENCES
(2022)
Article
Engineering, Biomedical
Ali F. Khan, Fan Zhang, Han Yuan, Lei Ding
Summary: A novel brain-wide DOT (BW-DOT) framework was developed to reconstruct a comprehensive set of RSNs and their subnetworks, showing statistically significant similarities to fMRI RSN templates.
JOURNAL OF NEURAL ENGINEERING
(2021)
Review
Chemistry, Multidisciplinary
Shinpei Okawa, Yoko Hoshi
Summary: Diffuse optical tomography (DOT) is a biomedical imaging modality that reconstructs hemoglobin concentration and oxygen saturation by detecting light passing through biological tissues. However, achieving high spatial resolution and quantification accuracy with DOT has been challenging due to diffusive light propagation in tissues with strong scattering and absorption. Recent efforts have focused on developing image reconstruction algorithms and utilizing advanced technologies such as artificial intelligence to improve DOT image reconstruction. This review discusses the forward calculation process and optimization techniques for better spatial resolution and quantification in DOT.
APPLIED SCIENCES-BASEL
(2023)
Article
Neurosciences
Kalyan Tripathy, Zachary E. Markow, Andrew K. Fishell, Arefeh Sherafati, Tracy M. Burns-Yocum, Mariel L. Schroeder, Alexandra M. Svoboda, Adam T. Eggebrecht, Mark A. Anastasio, Bradley L. Schlaggar, Joseph P. Culver
Summary: This study evaluated the feasibility and performance of decoding with high-density diffuse optical tomography (HD-DOT) in the visual cortex. The results showed that HD-DOT can accurately and reproducibly decode visual stimulus information at the single-trial level, as well as perform more complex non-binary decoding.
Article
Computer Science, Information Systems
Ganesh M. Balasubramaniam, Ben Wiesel, Netanel Biton, Rajnish Kumar, Judy Kupferman, Shlomi Arnon
Summary: This article discusses the application of deep learning algorithms in diffuse optical tomography and reviews the current state-of-the-art systems. Deep learning algorithms have been successful in image reconstruction, overcoming the distortion caused by photon absorption and multi-scattering.
Article
Neurosciences
Ernesto E. Vidal-Rosas, Alexander von Luehmann, Paola Pinti, Robert J. Cooper
Summary: Recent progress in optoelectronics has made it possible for the first time to develop wearable and high-density functional near-infrared spectroscopy (fNIRS) and diffuse optical tomography (DOT) technologies. These technologies have the potential to revolutionize real-world neuroscience by enabling functional neuroimaging of the human cortex at a resolution comparable to fMRI in any environment and population. This article provides an overview of the history and current status of wearable high-density fNIRS and DOT approaches, discusses ongoing challenges, and offers insights into the future of this remarkable technology.
Article
Neurosciences
Jiaming Cao, Eli Bulger, Barbara Shinn-Cunningham, Pulkit Grover, Jana M. Kainerstorfer
Summary: Electroencephalography (EEG) and diffuse optical tomography (DOT) are two imaging methods used in neuroimaging. EEG has high temporal resolution but limited spatial resolution, while DOT has high spatial resolution but limited temporal resolution. In previous work, computer simulations showed that combining the results of DOT reconstruction with EEG source reconstruction could improve spatio-temporal resolution. This work experimentally validates the algorithm by alternatingly flashing visual stimuli at a faster speed than the temporal resolution of DOT, demonstrating improved spatial confinement and temporal resolution with the joint reconstruction using both EEG and DOT.
Article
Computer Science, Information Systems
Vicky Mudeng, Wahdiyatun Nisa, Sena Sukmananda
Summary: This study develops a frequency-domain diffuse optical tomography (DOT) algorithm that investigates functional and structural information in biological tissue by numerically simulating light radiance distribution and reconstructing absorption and reduced scattering coefficients. The results show that the performance of the multi-frequency method with two frequencies is similar to the single-frequency method.
JOURNAL OF KING SAUD UNIVERSITY-COMPUTER AND INFORMATION SCIENCES
(2022)
Article
Engineering, Electrical & Electronic
Manob Jyoti Saikia
Summary: This article presents a spectroscopic diffuse optical tomography system for noninvasive continuous tissue imaging. It utilizes an embedded system architecture and algorithms to control the system, acquire data, perform noise-free lock-in detection, and wirelessly transmit data to a host computer. The system is capable of high-speed 3-D functional imaging and has potential for further miniaturization and development into a low-cost handheld device for real-time onsite tissue imaging.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2021)
Article
Oncology
Julia E. McGuinness, Mirella L. Altoe, Alessandro Marone, Lauren E. Franks, Shing M. Lee, Hyun K. Kim, Mariella Tejada, Meghna S. Trivedi, Melissa K. Accordino, Katherine D. Crew, Dawn L. Hershman, Andreas H. Hielscher, Kevin Kalinsky
Summary: The study demonstrated that DOTBIS-derived measurements of hemoglobin concentrations were consistently decreased in the tumor volume, while there were minimal changes observed in the contralateral breast. This suggests that DOTBIS may be a potential imaging assessment tool for evaluating responses to neoadjuvant targeted therapies in early stage breast cancer.
BREAST CANCER RESEARCH AND TREATMENT
(2021)
Article
Biochemical Research Methods
Yongyi Zhao, Ankit Raghuram, Fay Wang, Stephen Hyunkeol Kim, Andreas Hielscher, Jacob T. T. Robinson, Ashok Veeraraghavan
Summary: In this study, we utilized a data-driven unrolled network as our ToF-DOT inverse solver, which is faster and achieves higher reconstruction quality by accounting for model mismatch. Through training and testing on simulated and real-world data, and benchmarking against physics-based and learning-based inverse solvers, we demonstrated the state-of-the-art performance of our model in terms of speed and reconstruction quality.
JOURNAL OF BIOMEDICAL OPTICS
(2023)
Article
Astronomy & Astrophysics
Satoshi Hamano, Naoto Kobayashi, Hideyo Kawakita, Keiichi Takenaka, Yuji Ikeda, Noriyuki Matsunaga, Sohei Kondo, Hiroaki Sameshima, Kei Fukue, Shogo Otsubo, Akira Arai, Chikako Yasui, Hitomi Kobayashi, Giuseppe Bono, Ivo Saviane
Summary: We searched for diffuse interstellar bands (DIBs) in the near-infrared (NIR) spectra of 31 reddened early-type stars and discovered 54 DIBs, including 25 newly detected ones. The study found that the NIR DIBs have narrower FWHM values compared to the optical DIBs, indicating that longer wavelength DIBs are likely caused by larger molecules. The total column densities of the DIB carriers tend to decrease with increasing DIB wavelength, suggesting that larger carriers with higher oscillator strengths are responsible for the longer wavelength DIBs.
ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES
(2022)
Article
Mathematics, Applied
Philipp Zimmermann
Summary: In this article, we discuss a nonlocal analog of an inverse problem in diffuse optical tomography. We prove that if two pairs of diffusion and absorption coefficients (?(j), q(j)), j = 1, 2, satisfy q(1) = q(2) in the measurement set W and generate the same DN data, then they must be equal in Rn and ?, respectively. Furthermore, we demonstrate that the condition q1|W = q2|W is optimal because without this restriction, two distinct pairs (?(j), q(j)), j = 1, 2 can be constructed to generate the same DN data.
Article
Chemistry, Inorganic & Nuclear
Yuyao Guan, Yite Li, Junli Zhou, Tao Zhang, Jun Ding, Zhigang Xie, Lei Wang
Summary: This study developed a solid adsorbent based on metal-organic frameworks using defect-engineering strategy which showed great promise for handling radioactive iodine waste.
INORGANIC CHEMISTRY
(2021)
Article
Engineering, Environmental
Yite Li, Junli Zhou, Yuannan Chen, Qing Pei, Yao Li, Lei Wang, Zhigang Xie
Summary: A novel sulfonating strategy was reported to synthesize a spindle-shaped metal-organic framework with enhanced near-infrared absorption. The sulfonated material showed improved photoactivity under near-infrared irradiation and effectively triggered immunogenic cell death.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Applied
Junli Zhou, Yite Li, Lei Wang, Zhigang Xie
Summary: The study synthesized ACF@PCN-222@MnO2-PEG (APM) nanoparticles with good colloidal stability, biocompatibility and H2O2-triggered drug releasing. The amorphous MnO2 layer on APM's surface quickly decomposes after reacting with endogenous H2O2 to generate abundant oxygen, compensating for the oxygen consumed during photodynamic process.
Article
Physics, Multidisciplinary
Shibing Zhang, Zhen Sun, Junli Zhou, Bo Yang, Jiuchang Zhang, Zhihao Cui
Summary: The article introduces a new method for modeling the ITZ characteristics of concrete-like materials using random three-phase mesostructural modeling. Through finite element analysis, it was found that this method can effectively simulate the mesostructure and ITZ characteristics of concrete-like materials, with good agreement between numerical and experimental results.
FRONTIERS IN PHYSICS
(2021)
Review
Construction & Building Technology
Xue Xiao, Junli Zhou, Wei Yang
Summary: This paper summarizes calculation models for unsteady natural ventilation, which involve continuous airflow, pulsating flow, eddy penetration, and diffusion phenomena. The theories of different ventilation mechanisms and the differences between various research reports are expounded and discussed.
INDOOR AND BUILT ENVIRONMENT
(2022)
Article
Chemistry, Inorganic & Nuclear
Junli Zhou, Liqian Liu, Yite Li, Lei Wang, Zhigang Xie
Summary: In this study, a nanoscale Ru-doped metal-organic framework Hf-Ru with framework-boosted photoactivities was prepared, showing superior performance in bioimaging and ROS generation compared to molecular agents. The enhanced cellular uptake and imaging capabilities of Hf-Ru nanocrystals were well demonstrated in vitro.
INORGANIC CHEMISTRY
(2022)
Article
Immunology
Juan Li, Yiyong Wei, Junli Zhou, Helin Zou, Lulin Ma, Chengxi Liu, Zhi Xiao, Xingfeng Liu, Xinran Tan, Tian Yu, Song Cao
Summary: Selective activation of the LC:SC pathway alleviates neuropathic pain in mice by increasing noradrenaline release and reducing neuroinflammation of astrocytes and microglia in the spinal dorsal horn.
JOURNAL OF NEUROINFLAMMATION
(2022)
Review
Multidisciplinary Sciences
Jian Li, Kuanji Zhou, Zheng Wang, Junli Zhou, Xing Wang Deng
Summary: As one of the most important staple crops, wheat breeders strive to increase yield. Hybrid wheat is a preferred method to achieve this. This article summarizes the systems for hybrid wheat breeding based on recessive nuclear male-sterile mutants and discusses possible solutions to promote commercial-scale application.
CHINESE SCIENCE BULLETIN-CHINESE
(2022)
Article
Biochemistry & Molecular Biology
Yi Li, Xupin Jiang, Ze Zhang, Jie Liu, Chao Wu, Ying Chen, Junli Zhou, Jiaping Zhang, Xuanfen Zhang
Summary: Autophagy plays a pivotal role in the directed migration of endothelial cells guided by electric fields, and this process is mediated by the ROS/SIRT1/FOXO1 pathway.
FREE RADICAL BIOLOGY AND MEDICINE
(2022)
Article
Chemistry, Physical
Zhonghui Wu, Xinjian He, Junli Zhou, Xiongzhi Yang, Linghao Sun, Hehong Li, Yuede Pan, Lin Yu
Summary: This study presents a novel Ni(OH)2/C/PP separator modification approach for lithium-sulfur batteries, which effectively alleviates the shuttle effect and enhances the electrochemical performance of the batteries, including capacity, rate performance, and cyclability.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Nanoscience & Nanotechnology
Xiongzhi Yang, Jinzhu Jia, Linghao Sun, Guangsheng Huang, Junli Zhou, Ruanming Liao, Zhonghui Wu, Lin Yu, Zhenbo Wang
Summary: The regeneration of harmful activated sludge into an energy source is a valuable strategy for municipal sludge treatment and recycling. In this study, SiO2-modified N,S auto-doped porous carbon (NSC@SiO2) was successfully obtained through a simple calcination method. The introduction of P-doped NSC@SiO2 (NSPC@SiO2) further enhanced its surface area, pore volume, and carbon defects, making it an excellent sulfur host for lithium-sulfur batteries.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Inorganic & Nuclear
Yang Xiao-Lan, Wu Zhong-Hui, Zhang Ya-Jun, He Xin-Jian, Jia Jin-Zhu, Yang Xiong-Zhi, Zhou Jun-Li
Summary: NiCo2O4@CC composites, with a needle-like network structure, exhibit excellent performance in adsorbing polysulfide and alleviating volume expansion in lithium-sulfur batteries, showing good cycling performance.
CHINESE JOURNAL OF INORGANIC CHEMISTRY
(2021)
Article
Materials Science, Biomaterials
Junli Zhou, Yite Li, Lei Wang, Zhigang Xie
Summary: Photoactive MOF-based delivery systems have great potential for photodynamic therapy, with the study of porphyrinic MOF isomers revealing the impact of molecular distances and polarization on photoactivity. The confirmed endocytic pathways, cytotoxicity, and biocompatibility of these isomers without chemical modification provide new insights for in vivo applications and clinical translation.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Agronomy
Lei Chen, Gang Gu, Chengxu Wang, Zhufeng Chen, Wei Yan, Man Jin, Gang Xie, Junli Zhou, Xing Wang Deng, Xiaoyan Tang
Summary: Herbicide resistance is valuable for integrated weed management in agriculture, particularly in rice fields where weedy rice poses a challenge. This study obtained three mutant variants of the OsALS gene in rice through ethyl methyl sulfonate mutagenesis, with W-548 M mutant showing high levels of resistance to a broad spectrum of herbicides. The stable inheritance of herbicide resistance in rice lines makes W-548 M mutation a valuable resource for breeding herbicide resistant rice and weed management.
Article
Environmental Sciences
Junli Zhou, Yong Hua, Yuan Xiao, Cheng Ye, Wei Yang
Summary: This paper presents a detailed analysis of the ventilation effectiveness in a building with a single opening, evaluating the impact of various parameters on ventilation efficiency and establishing a mixing coefficient for predicting the short-circuit ratio of ventilation rate through openings.
AEROSOL AND AIR QUALITY RESEARCH
(2021)