Targeting Pancreatic Ductal Adenocarcinoma Acidic Microenvironment

Molecular imaging in pancreatic cancer – A roadmap for therapeutic decisions

(2013) Gabriela Kramer-Marek et al.   CANCER LETTERS

Cancer heterogeneity—a multifaceted view

(2013) Felipe De Sousa E Melo et al.   EMBO REPORTS

A High-Fat Diet Activates Oncogenic Kras and COX2 to Induce Development of Pancreatic Ductal Adenocarcinoma in Mice

(2013) Bincy Philip et al.   GASTROENTEROLOGY

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

(2013) Jaekyoung Son et al.   NATURE

The causes and consequences of genetic heterogeneity in cancer evolution

(2013) Rebecca A. Burrell et al.   NATURE

Family of pH (low) insertion peptides for tumor targeting

(2013) D. Weerakkody et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient 18F-Labeling of Large 37-Amino-Acid pHLIP Peptide Analogues and Their Biological Evaluation

(2012) Pierre Daumar et al.   BIOCONJUGATE CHEMISTRY

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Chronic Autophagy Is a Cellular Adaptation to Tumor Acidic pH Microenvironments

(2012) Jonathan W. Wojtkowiak et al.   CANCER RESEARCH

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

In Vivo pH Imaging with 99mTc-pHLIP

(2012) Sven Macholl et al.   MOLECULAR IMAGING AND BIOLOGY

Proteomic Analysis Reveals Warburg Effect and Anomalous Metabolism of Glutamine in Pancreatic Cancer Cells

(2011) Weidong Zhou et al.   JOURNAL OF PROTEOME RESEARCH

Imaging pH and metastasis

(2011) Arig Ibrahim Hashim et al.   NMR IN BIOMEDICINE

The Spatial Organization of Proton and Lactate Transport in a Rat Brain Tumor

(2011) Emmanuelle Grillon et al.   PLoS One

Blinded by the Light: Molecular Imaging in Pancreatic Adenocarcinoma

(2010) E. Collisson et al.   CLINICAL CANCER RESEARCH

Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

(2010) Johanna Chiche et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Measuring Tumor Aggressiveness and Targeting Metastatic Lesions with Fluorescent pHLIP

(2010) Yana K. Reshetnyak et al.   MOLECULAR IMAGING AND BIOLOGY

pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents

(2010) Oleg A. Andreev et al.   MOLECULAR MEMBRANE BIOLOGY

A Novel Technology for the Imaging of Acidic Prostate Tumors by Positron Emission Tomography

(2009) A. L. Vavere et al.   CANCER RESEARCH

Robust acinar cell transgene expression of CreErT via BAC recombineering

(2008) Baoan Ji et al.   GENESIS

Causes and Consequences of Increased Glucose Metabolism of Cancers

(2008) R. J. Gillies et al.   JOURNAL OF NUCLEAR MEDICINE

Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases

(2007) Z XIONG et al.   CURRENT OPINION IN PHARMACOLOGY