Computational Assay of H7N9 Influenza Neuraminidase Reveals R292K Mutation Reduces Drug Binding Affinity

Influenza virus resistance to neuraminidase inhibitors

(2013) Mélanie Samson et al.   ANTIVIRAL RESEARCH

Global Assessment of Resistance to Neuraminidase Inhibitors, 2008–2011: The Influenza Resistance Information Study (IRIS)

(2013) Richard J. Whitley et al.   CLINICAL INFECTIOUS DISEASES

Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance

(2013) Yunwen Hu et al.   LANCET

Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome

(2013) Yu Chen et al.   LANCET

Genomic signature and protein sequence analysis of a novel influenza A (H7N9) virus that causes an outbreak in humans in China

(2013) Qi Liu et al.   MICROBES AND INFECTION

The genesis and source of the H7N9 influenza viruses causing human infections in China

(2013) Tommy Tsan-Yuk Lam et al.   NATURE

Global Concerns Regarding Novel Influenza A (H7N9) Virus Infections

(2013) Timothy M. Uyeki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Resistance to Neuraminidase Inhibitors Conferred by an R292K Mutation in a Human Influenza Virus H7N9 Isolate Can Be Masked by a Mixed R/K Viral Population

(2013) H.- L. Yen et al.   mBio

Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding

(2013) Yan Wu et al.   Scientific Reports

Probable person to person transmission of novel avian influenza A (H7N9) virus in Eastern China, 2013: epidemiological investigation

(2013) X. Qi et al.   BMJ-British Medical Journal

A fatal case caused by novel H7N9 avian influenza A virus in China

(2013) Feifei Yang et al.   Emerging Microbes & Infections

Long Time Scale GPU Dynamics Reveal the Mechanism of Drug Resistance of the Dual Mutant I223R/H275Y Neuraminidase from H1N1-2009 Influenza Virus

(2012) Christopher J. Woods et al.   BIOCHEMISTRY

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 1. Generalized Born

(2012) Andreas W. Götz et al.   Journal of Chemical Theory and Computation

Systematic review of influenza resistance to the neuraminidase inhibitors

(2011) Kristian Thorlund et al.   BMC INFECTIOUS DISEASES

A water-swap reaction coordinate for the calculation of absolute protein–ligand binding free energies

(2011) Christopher J. Woods et al.   JOURNAL OF CHEMICAL PHYSICS

Mechanism of 150-cavity formation in influenza neuraminidase

(2011) Rommie E. Amaro et al.   Nature Communications