3.8 Article

Simulation of blood flow in a small-diameter vascular graft model with a swirl (spiral) flow guider

Journal

SCIENCE IN CHINA SERIES C-LIFE SCIENCES
Volume 51, Issue 10, Pages 913-921

Publisher

SCIENCE PRESS
DOI: 10.1007/s11427-008-0118-5

Keywords

arterial prosthesis; acute thrombus formation; flow simulation; swirling (spiral) flow

Categories

Funding

  1. National Natural Science Foundation of China [10632010]

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Small-diameter vascular grafts are in large demand for coronary and peripheral bypass procedures, but present products still fail in long-term clinical application. In the present communication, a new type of small-diameter graft with a swirl flow guider was proposed to improve graft patency rate. Flow pattern in the graft was simulated numerically and compared with that in a conventional graft. The numerical results revealed that the swirl flow guider could indeed make the blood flow rotate in the new graft. The swirling flow distal to the flow guider significantly altered the flow pattern in the new graft and the velocity profiles were re-distributed. Due to the swirling flow, the blood velocity near the vessel wall and wall shear rate were greatly enhanced. We believe that the increased blood velocity near the wall and the wall shear rate can impede the occurrence of acute thrombus formation and intimal hyperplasia, hence can improve the graft patency rate for long-term clinical use.

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