Acid–base dysregulation and chemosensory mechanisms in panic disorder: a translational update

The Human Ortholog of Acid-Sensing Ion Channel Gene ASIC1a Is Associated With Panic Disorder and Amygdala Structure and Function

(2014) Jordan W. Smoller et al.   BIOLOGICAL PSYCHIATRY

Brainstem response to hypercapnia: A symptom provocation study into the pathophysiology of panic disorder

(2014) Liesbet Goossens et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Etiology, triggers and neurochemical circuits associated with unexpected, expected, and laboratory-induced panic attacks

(2014) Philip L. Johnson et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Early-life risk factors for panic and separation anxiety disorder: Insights and outstanding questions arising from human and animal studies of CO2 sensitivity

(2014) Marco Battaglia et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The Deakin/Graeff hypothesis: Focus on serotonergic inhibition of panic

(2014) Evan D. Paul et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Respiratory manifestations of panic disorder in animals and humans: A unique opportunity to understand how supramedullary structures regulate breathing

(2014) Richard Kinkead et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls

(2014) Jiann Wei Yeoh et al.   Frontiers in Neuroscience

Abnormal Activity-Dependent Brain Lactate and Glutamate+Glutamine Responses in Panic Disorder

(2013) Richard J. Maddock et al.   BIOLOGICAL PSYCHIATRY

Functional T1ρ Imaging in Panic Disorder

(2013) Vincent A. Magnotta et al.   BIOLOGICAL PSYCHIATRY

Carbon dioxide inhalation as a human experimental model of panic: The relationship between emotions and cardiovascular physiology

(2013) Nicole K. Leibold et al.   BIOLOGICAL PSYCHOLOGY

Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride

(2013) Tarunya Arun et al.   BRAIN

Modeling panic disorder in rodents

(2013) Fabrício A. Moreira et al.   CELL AND TISSUE RESEARCH

Anxiolytic effects of vestipitant in a sub-group of healthy volunteers known to be sensitive to CO2 challenge

(2013) Stefano Zanone Poma et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Fear and panic in humans with bilateral amygdala damage

(2013) Justin S Feinstein et al.   NATURE NEUROSCIENCE

Acid-sensing ion channels in pain and disease

(2013) John A. Wemmie et al.   NATURE REVIEWS NEUROSCIENCE

The nature of feelings: evolutionary and neurobiological origins

(2013) Antonio Damasio et al.   NATURE REVIEWS NEUROSCIENCE

A group of non-serotonergic cells is CO2-stimulated in the medullary raphé

(2013) K.E. Iceman et al.   NEUROSCIENCE

Characteristics of individuals meeting criteria for new onset panic attacks following exposure to a typhoon

(2013) Roxann Roberson-Nay et al.   PSYCHIATRY RESEARCH

The carbon dioxide challenge test in panic disorder: a systematic review of preclinical and clinical research

(2013) Julio Mario Xerfan do Amaral et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

COMORBIDITY AND DISEASE BURDEN IN THE NATIONAL COMORBIDITY SURVEY REPLICATION (NCS-R)

(2012) Anne M. Gadermann et al.   DEPRESSION AND ANXIETY

Revise the revised? New dimensions of the neuroanatomical hypothesis of panic disorder

(2012) Thomas Dresler et al.   JOURNAL OF NEURAL TRANSMISSION

Activation of the Orexin 1 Receptor is a Critical Component of CO2-Mediated Anxiety and Hypertension but not Bradycardia

(2012) Philip L Johnson et al.   NEUROPSYCHOPHARMACOLOGY

An animal model of panic vulnerability with chronic disinhibition of the dorsomedial/perifornical hypothalamus

(2012) Philip L. Johnson et al.   PHYSIOLOGY & BEHAVIOR

Detecting activity-evoked pH changes in human brain

(2012) V. A. Magnotta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploration of a possible association between the tryptophan hydroxylase 2 (TPH2) gene and panic symptoms induced by carbon dioxide in healthy individuals

(2012) Ryo Abe et al.   PSYCHIATRY RESEARCH

Do Unexpected Panic Attacks Occur Spontaneously?

(2011) Alicia E. Meuret et al.   BIOLOGICAL PSYCHIATRY

Caffeine challenge test and panic disorder: a systematic literature review

(2011) Marina Machado Vilarim et al.   Expert Review of Neurotherapeutics

Redefining the components of central CO2chemosensitivity - towards a better understanding of mechanism

(2011) Robert T. R. Huckstepp et al.   JOURNAL OF PHYSIOLOGY-LONDON

Preliminary evidence of anxiolytic effects of the CRF1 receptor antagonist R317573 in the 7.5% CO2 proof-of-concept experimental model of human anxiety

(2011) Jayne E Bailey et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Evidence of a suffocation alarm system within the periaqueductal gray matter of the rat

(2011) F.G. Schimitel et al.   NEUROSCIENCE

Unstable Maternal Environment, Separation Anxiety, and Heightened CO2 Sensitivity Induced by Gene-by-Environment Interplay

(2011) Francesca R. D'Amato et al.   PLoS One

Effects of tryptophan depletion and tryptophan loading on the affective response to high-dose CO2 challenge in healthy volunteers

(2011) Alessandro Colasanti et al.   PSYCHOPHARMACOLOGY

Involvement of the peripheral nervous system in synucleinopathies, tauopathies and other neurodegenerative proteinopathies of the brain

(2010) Koichi Wakabayashi et al.   ACTA NEUROPATHOLOGICA

Incidence and Risk Patterns of Anxiety and Depressive Disorders and Categorization of Generalized Anxiety Disorder

(2010) Katja Beesdo et al.   ARCHIVES OF GENERAL PSYCHIATRY

Carbon Dioxide Hypersensitivity in Separation-Anxious Offspring of Parents with Panic Disorder

(2010) Roxann Roberson-Nay et al.   BIOLOGICAL PSYCHIATRY

The Human Amygdala and the Induction and Experience of Fear

(2010) Justin S. Feinstein et al.   CURRENT BIOLOGY

The impact of panic-agoraphobic comorbidity on suicidality in hospitalized patients with major depression

(2010) Lily A. Brown et al.   DEPRESSION AND ANXIETY

CO2 chemoreception in cardiorespiratory control

(2010) Robert W. Putnam   JOURNAL OF APPLIED PHYSIOLOGY

Flight behaviour in humans is intensified by a candidate genetic risk factor for panic disorder: evidence from a translational model of fear and anxiety

(2010) A M Perkins et al.   MOLECULAR PSYCHIATRY

A Genetically Informed Study of the Association Between Childhood Separation Anxiety, Sensitivity to CO2, Panic Disorder, and the Effect of Childhood Parental Loss

(2009) Marco Battaglia et al.   ARCHIVES OF GENERAL PSYCHIATRY

A Tryptophan Hydroxylase 2 Gene Polymorphism is Associated with Panic Disorder

(2009) Yong-Ku Kim et al.   BEHAVIOR GENETICS

Acid-sensing by the T cell death-associated gene 8 (TDAG8) receptor cloned from rat brain

(2009) Jennifer McGuire et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Association of a Polyadenylation Polymorphism in the Serotonin Transporter and Panic Disorder

(2009) Sandeep Gyawali et al.   BIOLOGICAL PSYCHIATRY

The Amygdala Is a Chemosensor that Detects Carbon Dioxide and Acidosis to Elicit Fear Behavior

(2009) Adam E. Ziemann et al.   CELL

Blood Lactate is an Important Energy Source for the Human Brain

(2009) Gerrit van Hall et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Induction of panic attack by stimulation of the ventromedial hypothalamus

(2009) W. Bryan Wilent et al.   JOURNAL OF NEUROSURGERY

Review: Acids in the brain: a factor in panic?

(2009) G. Esquivel et al.   JOURNAL OF PSYCHOPHARMACOLOGY

A key role for orexin in panic anxiety

(2009) Philip L Johnson et al.   NATURE MEDICINE

A comparison of the effects of a subtype selective and non-selective benzodiazepine receptor agonist in two CO2 models of experimental human anxiety

(2008) JE Bailey et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Panic disorder is associated with the serotonin transporter gene (SLC6A4) but not the promoter region (5-HTTLPR)

(2008) L J Strug et al.   MOLECULAR PSYCHIATRY

Elevated brain lactate responses to neural activation in panic disorder: a dynamic 1H-MRS study

(2008) R J Maddock et al.   MOLECULAR PSYCHIATRY

Exaggerated compensatory response to acute respiratory alkalosis in panic disorder is induced by increased lactic acid production

(2008) Y. Ueda et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Carbon Dioxide-Induced Emotion and Respiratory Symptoms in Healthy Volunteers

(2008) Alessandro Colasanti et al.   NEUROPSYCHOPHARMACOLOGY

Neurobiology of panic disorder: From animal models to brain neuroimaging

(2008) Frederico G. Graeff et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Regional gray matter abnormalities in panic disorder: A voxel-based morphometry study

(2008) Ricardo R. Uchida et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Role of chemoreceptors in mediating dyspnea

(2008) Gordon F. Buchanan et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

A twin study of the common vulnerability between heightened sensitivity to hypercapnia and panic disorder

(2007) Marco Battaglia et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS