Silver nanoparticles – wolves in sheep's clothing?

Fast intracellular dissolution and persistent cellular uptake of silver nanoparticles in CHO-K1 cells: implication for cytotoxicity

(2014) Xiumei Jiang et al.   Nanotoxicology

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release

(2014) Anda R Gliga et al.   Particle and Fibre Toxicology

Size-Dependent Toxicity of Silver Nanoparticles to Bacteria, Yeast, Algae, Crustaceans and Mammalian Cells In Vitro

(2014) Angela Ivask et al.   PLoS One

Integrated mRNA and micro RNA profiling reveals epigenetic mechanism of differential sensitivity of Jurkat T cells to AgNPs and Ag ions

(2014) Hyun-Jeong Eom et al.   TOXICOLOGY LETTERS

Carbon black and titanium dioxide nanoparticles induce distinct molecular mechanisms of toxicity

(2014) Sonja Boland et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Quantification of the Uptake of Silver Nanoparticles and Ions to HepG2 Cells

(2013) Su-juan Yu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Species Differences Take Shape at Nanoparticles: Protein Corona Made of the Native Repertoire Assists Cellular Interaction

(2013) Yuya Hayashi et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Revealing the Binding Structure of the Protein Corona on Gold Nanorods Using Synchrotron Radiation-Based Techniques: Understanding the Reduced Damage in Cell Membranes

(2013) Liming Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multi-platform genotoxicity analysis of silver nanoparticles in the model cell line CHO-K1

(2013) Xiumei Jiang et al.   TOXICOLOGY LETTERS

Programmed Cell Death: Molecular Mechanisms and Implications for Safety Assessment of Nanomaterials

(2012) Fernando Torres Andón et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chemical Transformations of Nanosilver in Biological Environments

(2012) Jingyu Liu et al.   ACS Nano

Scavenger Receptor Mediated Endocytosis of Silver Nanoparticles into J774A.1 Macrophages Is Heterogeneous

(2012) Hongyun Wang et al.   ACS Nano

The effects of sub-lethal concentrations of silver nanoparticles on inflammatory and stress genes in human macrophages using cDNA microarray analysis

(2012) Dae-Hyoun Lim et al.   BIOMATERIALS

Bacterial Effects and Protein Corona Evaluations: Crucial Ignored Factors in the Prediction of Bio-Efficacy of Various Forms of Silver Nanoparticles

(2012) Ali Akbar Ashkarran et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Cysteine-Induced Modifications of Zero-valent Silver Nanomaterials: Implications for Particle Surface Chemistry, Aggregation, Dissolution, and Silver Speciation

(2012) Andreas P. Gondikas et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Cytotoxicity Induced by Engineered Silver Nanocrystallites Is Dependent on Surface Coatings and Cell Types

(2012) Anil K. Suresh et al.   LANGMUIR

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Alterations in physical state of silver nanoparticles exposed to synthetic human stomach fluid

(2012) Kim R. Rogers et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Global Gene Expression Profiling of Human Lung Epithelial Cells After Exposure to Nanosilver

(2012) Rasmus Foldbjerg et al.   TOXICOLOGICAL SCIENCES

Butachlor induced dissipation of mitochondrial membrane potential, oxidative DNA damage and necrosis in human peripheral blood mononuclear cells

(2012) Sourabh Dwivedi et al.   TOXICOLOGY

Genotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in BEAS 2B cells

(2012) Penny Nymark et al.   TOXICOLOGY

Silver nanoparticles-mediated G2/M cycle arrest of renal epithelial cells is associated with NRF2-GSH signaling

(2012) Su Jin Kang et al.   TOXICOLOGY LETTERS

Application of Laser Postionization Secondary Neutral Mass Spectrometry/Time-of-Flight Secondary Ion Mass Spectrometry in Nanotoxicology: Visualization of Nanosilver in Human Macrophages and Cellular Responses

(2011) Andrea Haase et al.   ACS Nano

Characterization of Translocation of Silver Nanoparticles and Effects on Whole-Genome Gene Expression Using an In Vitro Intestinal Epithelium Coculture Model

(2011) Hans Bouwmeester et al.   ACS Nano

Silver nanoparticles induce apoptosis and G2/M arrest via PKCζ-dependent signaling in A549 lung cells

(2011) Young Sook Lee et al.   ARCHIVES OF TOXICOLOGY

Nuclear Targeted Silver Nanospheres Perturb the Cancer Cell Cycle Differently than Those of Nanogold

(2011) Lauren A. Austin et al.   BIOCONJUGATE CHEMISTRY

The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles

(2011) Margriet V.D.Z. Park et al.   BIOMATERIALS

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Mechanism of Silver Nanoparticle Toxicity Is Dependent on Dissolved Silver and Surface Coating in Caenorhabditis elegans

(2011) Xinyu Yang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Endoplasmic reticulum stress signaling is involved in silver nanoparticles-induced apoptosis

(2011) Rui Zhang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The devil is in the details (or the surface): impact of surface structure and surface energetics on understanding the behavior of nanomaterials in the environment

(2011) Imali A. Mudunkotuwa et al.   JOURNAL OF ENVIRONMENTAL MONITORING

Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles

(2011) Marco P. Monopoli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aggregation and Dissolution of 4 nm ZnO Nanoparticles in Aqueous Environments: Influence of pH, Ionic Strength, Size, and Adsorption of Humic Acid

(2011) Shao-Wei Bian et al.   LANGMUIR

Genotoxic effects of silver nanoparticles stimulated by oxidative stress in human normal bronchial epithelial (BEAS-2B) cells

(2011) Ha Ryong Kim et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Characterization of synthesized silver nanoparticles and assessment of its genotoxicity potentials using the alkaline comet assay

(2011) Natesan A.L. Flower et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Genotoxicity of silver nanoparticles evaluated using the Ames test and in vitro micronucleus assay

(2011) Yan Li et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Full Assessment of Fate and Physiological Behavior of Quantum Dots UtilizingCaenorhabditis elegansas a Model Organism

(2011) Ying Qu et al.   NANO LETTERS

Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials

(2011) Feng Zhao et al.   Small

Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells

(2011) Nana Asare et al.   TOXICOLOGY

Toxicity of silver nanoparticles—Nanoparticle or silver ion?

(2011) Christiane Beer et al.   TOXICOLOGY LETTERS

Controlled Release of Biologically Active Silver from Nanosilver Surfaces

(2010) Jingyu Liu et al.   ACS Nano

Uptake and intracellular distribution of silver nanoparticles in human mesenchymal stem cells

(2010) C. Greulich et al.   Acta Biomaterialia

Cytotoxicity and genotoxicity of silver nanoparticles in the human lung cancer cell line, A549

(2010) Rasmus Foldbjerg et al.   ARCHIVES OF TOXICOLOGY

Investigation of the cytotoxicity mechanism of silver nanoparticlesin vitro

(2010) Lina Wei et al.   Biomedical Materials

Toxicity of Silver Nanoparticles Increases during Storage Because of Slow Dissolution under Release of Silver Ions

(2010) S. Kittler et al.   CHEMISTRY OF MATERIALS

Signaling gene cascade in silver nanoparticle induced apoptosis

(2010) P. Gopinath et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Ion Release Kinetics and Particle Persistence in Aqueous Nano-Silver Colloids

(2010) Jingyu Liu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Silver nanoparticles in simulated biological media: a study of aggregation, sedimentation, and dissolution

(2010) Larissa V. Stebounova et al.   JOURNAL OF NANOPARTICLE RESEARCH

Heat shock proteins in toxicology: How close and how far?

(2010) Subash C. Gupta et al.   LIFE SCIENCES

Selective Targeting of Gold Nanorods at the Mitochondria of Cancer Cells: Implications for Cancer Therapy

(2010) Liming Wang et al.   NANO LETTERS

Impact of silver nanoparticles on human cells: Effect of particle size

(2010) Wei Liu et al.   Nanotoxicology

Silver Nanoparticles Disrupt GDNF/Fyn kinase Signaling in Spermatogonial Stem Cells

(2010) Laura K. Braydich-Stolle et al.   TOXICOLOGICAL SCIENCES

The New Toxicology of Sophisticated Materials: Nanotoxicology and Beyond

(2010) A. D. Maynard et al.   TOXICOLOGICAL SCIENCES

Silver nanoparticles: Evaluation of DNA damage, toxicity and functional impairment in human mesenchymal stem cells

(2010) Stephan Hackenberg et al.   TOXICOLOGY LETTERS

Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis

(2010) Mei Jing Piao et al.   TOXICOLOGY LETTERS

NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials

(2009) Neenu Singh et al.   BIOMATERIALS

In Vitro Toxicity of Silver Nanoparticles at Noncytotoxic Doses to HepG2 Human Hepatoma Cells

(2009) Koji Kawata et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology

(2009) G. Oberdörster   JOURNAL OF INTERNAL MEDICINE

Understanding the Role of Surface Charges in Cellular Adsorption versus Internalization by Selectively Removing Gold Nanoparticles on the Cell Surface with a I2/KI Etchant

(2009) Eun Chul Cho et al.   NANO LETTERS

Differential plasma protein binding to metal oxide nanoparticles

(2009) Zhou J Deng et al.   NANOTECHNOLOGY

Nano-silver – a review of available data and knowledge gaps in human and environmental risk assessment

(2009) Susan W.P. Wijnhoven et al.   Nanotoxicology

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

An evidence-based environmental perspective of manufactured silver nanoparticle in syntheses and applications: A systematic review and critical appraisal of peer-reviewed scientific papers

(2009) Thabet M. Tolaymat et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Effect of Surface Properties on Nanoparticle–Cell Interactions

(2009) Ayush Verma et al.   Small

Interactions of silver nanoparticles with primary mouse fibroblasts and liver cells

(2009) S. Arora et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Metallothionein protection of cadmium toxicity

(2009) Curtis D. Klaassen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism

(2009) Eun-Jung Park et al.   TOXICOLOGY IN VITRO

Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells

(2008) P. V. AshaRani et al.   ACS Nano

Toxicity of Silver Nanoparticles toChlamydomonas reinhardtii

(2008) Enrique Navarro et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Unique Cellular Interaction of Silver Nanoparticles: Size-Dependent Generation of Reactive Oxygen Species

(2008) C. Carlson et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Environmental toxicity, oxidative stress and apoptosis: Ménage à Trois

(2008) Rodrigo Franco et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology

DNA damage response to different surface chemistry of silver nanoparticles in mammalian cells

(2008) Maqusood Ahamed et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A high throughput in vitro analytical approach to screen for oxidative stress potential exerted by nanomaterials using a biologically relevant matrix: Human blood serum

(2008) E.J. Rogers et al.   TOXICOLOGY IN VITRO

Cellular responses induced by silver nanoparticles: In vitro studies

(2008) S. Arora et al.   TOXICOLOGY LETTERS

The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells

(2008) Yi-Hong Hsin et al.   TOXICOLOGY LETTERS