Cellular response to the genotoxic insult: the question of threshold for genotoxic carcinogens

Interleukin 6 downregulates p53 expression and activity by stimulating ribosome biogenesis: a new pathway connecting inflammation to cancer

(2014) E Brighenti et al.   ONCOGENE

Influence of DNA Repair on Nonlinear Dose-Responses for Mutation

(2013) Adam D. Thomas et al.   TOXICOLOGICAL SCIENCES

Biomarkers of Exposure and Effect in Human Lymphoblastoid TK6 Cells Following [13C2]-Acetaldehyde Exposure

(2013) Benjamin C. Moeller et al.   TOXICOLOGICAL SCIENCES

A Reversible Gene-Targeting Strategy Identifies Synthetic Lethal Interactions between MK2 and p53 in the DNA Damage Response In Vivo

(2013) Sandra Morandell et al.   Cell Reports

Quantitative approaches for assessing dose-response relationships in genetic toxicology studies

(2012) B.B. Gollapudi et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

The determination of exogenous formaldehyde in blood of rats during and after inhalation exposure

(2012) Anne J. Kleinnijenhuis et al.   FOOD AND CHEMICAL TOXICOLOGY

Persistence and Repair of Bifunctional DNA Adducts in Tissues of Laboratory Animals Exposed to 1,3-Butadiene by Inhalation

(2011) Melissa Goggin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Determination ofN2-Hydroxymethyl-dG Adducts in the Nasal Epithelium and Bone Marrow of Nonhuman Primates Following13CD2-Formaldehyde Inhalation Exposure

(2011) Benjamin C. Moeller et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Key studies used to support cancer risk assessment questioned

(2011) Edward J. Calabrese   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Posttranslational modification of mammalian AP endonuclease (APE1)

(2010) Carlos S. Busso et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular Dosimetry ofN2-Hydroxymethyl-dG DNA Adducts in Rats Exposed to Formaldehyde

(2010) Kun Lu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization

(2010) H. Christian Reinhardt et al.   MOLECULAR CELL

p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication

(2010) I. G. Cannell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distribution of DNA Adducts Caused by Inhaled Formaldehyde Is Consistent with Induction of Nasal Carcinoma but Not Leukemia

(2010) Kun Lu et al.   TOXICOLOGICAL SCIENCES

Dose-Response Relationships for N7-(2-Hydroxyethyl)Guanine Induced by Low-Dose [14C]Ethylene Oxide: Evidence for a Novel Mechanism of Endogenous Adduct Formation

(2009) D. A. Marsden et al.   CANCER RESEARCH

Nonlinear Cancer Response at Ultralow Dose: A 40800-Animal ED001Tumor and Biomarker Study

(2009) George S. Bailey et al.   CHEMICAL RESEARCH IN TOXICOLOGY

In vivo genotoxicity of EMS: Statistical assessment of the dose response curves

(2009) Elmar Gocke et al.   TOXICOLOGY LETTERS

Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons

(2008) Yo-Chan Jeong et al.   FREE RADICAL BIOLOGY AND MEDICINE

CHIP-Mediated Degradation and DNA Damage-Dependent Stabilization Regulate Base Excision Repair Proteins

(2008) Jason L. Parsons et al.   MOLECULAR CELL

No-observed effect levels are associated with up-regulation of MGMT following MMS exposure

(2008) Shareen H. Doak et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Biomarkers in Toxicology and Risk Assessment: Informing Critical Dose–Response Relationships

(2007) James A. Swenberg et al.   CHEMICAL RESEARCH IN TOXICOLOGY