Review
Biochemistry & Molecular Biology
Lamberta Ghaly, Vincent Bargnes, Sadiq Rahman, George-Abraam Tawfik, Sergio Bergese, William Caldwell
Summary: Complex regional pain syndrome (CRPS) is a rare and debilitating chronic pain disorder characterized by persistent pain that is disproportionate to any preceding injury. It can significantly impact a person's quality of life, resulting in disability and psychological distress. Despite being recognized for over a century, finding effective treatment for CRPS remains challenging.
Review
Medicine, General & Internal
Katarzyna Osiak, Agata Mazurek, Mateusz Koziej, Jerzy A. Walocha, Artur Pasternak
Summary: Electrodiagnostic testing plays a crucial role in the diagnosis and surgical treatment of CTS, providing a quantitative assessment of nerve physiological function. It can detect other pathologies and assist in determining reasons for surgical failure.
JOURNAL OF CLINICAL MEDICINE
(2021)
Editorial Material
Clinical Neurology
Vasudeva G. Iyer
Summary: This article presents a rare case of a common neurological disorder, diagnosed through clinical reasoning and additional investigations.
Article
Biochemistry & Molecular Biology
Cesar Fernandez-de-las-Penas, Stella Fuensalida-Novo, Jo Nijs, Annalie Basson, Gustavo Plaza-Manzano, Juan A. Valera-Calero, Lars Arendt-Nielsen, Ana I. de-la-Llave-Rincon
Summary: In 2021, the IASP proposed a grading system for classifying patients with carpal tunnel syndrome (CTS) into different pain phenotypes. The presence of a nociplastic or mixed-type pain phenotype in CTS patients may explain the lack of clinical effectiveness of selective treatments targeting the carpal tunnel area. Therefore, identifying the predominant pain phenotype in CTS patients is important for achieving better treatment outcomes.
Review
Medicine, General & Internal
Sheikh Azka Zaheer, Zubair Ahmed
Summary: Carpal tunnel syndrome (CTS) is a common condition that causes numbness and weakness in the hand and arm. Neurodynamic modulation techniques have been used as a non-surgical treatment for CTS, but their effectiveness has been unclear. This systematic review found that neurodynamic techniques significantly reduced symptom severity, pain, and motor latency in CTS patients, while improving nerve conduction velocities.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Orthopedics
Michael Abdallah, Elie Bou Sanayeh, Rami Haroun, Maria El Khoury, Majd El Hajj Moussa, Fadi Hoyek
Summary: This article presents a rare case of carpal tunnel syndrome (CTS) secondary to tumoral calcinosis and provides a summary of all published cases with similar conditions. CTS secondary to tumoral calcinosis is a rare benign condition that should be considered in the differential diagnosis of patients presenting with chronic CTS symptoms.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Rehabilitation
Nancy A. Baker, Julianna Dole, Shawn C. Roll
Summary: This study consolidated clinical treatment recommendations for CTS, classified them by strength of evidence, and summarized them into 12 broad treatment categories. Surgery, positioning, and steroids received strong support, while conservative treatments provided by rehabilitation professionals were conditionally supported.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Clinical Neurology
Jianjun Sun, Xiaodi Zou, Qinyun Fu, Jianhua Wu, Shuaishuai Yuan, Ahmad Alhaskawi, Yanzhao Dong, Haiying Zhou, Sahar Ahmed Abdalbary, Hui Lu
Summary: Carpal tunnel syndrome is a common peripheral neuropathy characterized by sensory disturbances, motor dysfunctions, and pain in the fingers and hand. This article presents a case study demonstrating the use of an ultrasound-guided needle knife technique to treat CTS, which proves to be a safe and effective minimally invasive therapeutic method, improving the patient's symptoms significantly.
FRONTIERS IN NEUROLOGY
(2023)
Article
Medicine, General & Internal
Stahs Pripotnev, Susan E. Mackinnon
Summary: Carpal tunnel release is a commonly performed procedure, with most patients experiencing improvement in their symptoms. However, there is a small subset of patients who may experience failure of the initial surgery. The management of these patients involves thorough clinical examination, electrodiagnostic studies, and step-wise surgical approaches for revision surgery.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Daniel Georg Gmainer, Andrzej Hecker, Petra Brinskelle, Alexander Draschl, Patrick Reinbacher, Lars-Peter Kamolz, David Benjamin Lumenta
Summary: This study aimed to identify differences in symptoms, signs, and intraoperative findings between recurrent and persistent carpal tunnel syndrome (CTS) cases after primary carpal tunnel release (CTR). The results showed that persistent CTS cases reported more frequent postoperative pain and longer duration of symptoms than recurrent cases. Scarring around the median nerve was more common in recurrent cases, while incomplete division of the palmar ligament was the primary cause for revision in persistent cases. Referring patients with symptoms persisting for more than three months after CTR to a certified hand clinic for additional evaluation is advisable.
Review
Surgery
S. M. Georgeto, G. L. Picharski, R. A. C. Andraus, R. A. da Silva, S. Ngomo, K. B. P. Fernandes
Summary: Carpal tunnel syndrome (CTS) is a common compressive neuropathy worldwide. This study conducted a systematic review to analyze the clinical and surgical outcomes of bilateral CTS treatment. It found that both clinical and surgical treatments can improve symptom severity, functional status, and pain intensity in patients with bilateral CTS during one-and three-month follow-up periods.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2022)
Article
Health Care Sciences & Services
Jui-Chien Wang, Chung-Yi Li, Po-Yen Ko, Tung-Tai Wu, Kuo-Chen Wu, Fong-Chin Su, I-Ming Jou, Po-Ting Wu
Summary: This study aimed to evaluate the correlation between carpal tunnel pressure (CTP) and the clinical presentations in patients with carpal tunnel syndrome (CTS), as well as explore the possible predictors for the postoperative recovery pattern. The results showed that preoperative CTP was well correlated with the clinical presentations and could be a useful predictor for the postoperative clinical recovery pattern.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Multidisciplinary Sciences
Oscar J. Pellicer-Valero, Jose D. Martin-Guerrero, Cesar Fernandez-de-las-Penas, Ana I. De-la-Llave-Rincon, Jorge Rodriguez-Jimenez, Esperanza Navarro-Pardo, Margarita I. Cigaran-Mendez
Summary: Identifying subgroups of patients with carpal tunnel syndrome using spectral clustering revealed three clusters with different clinical, psycho-physical, psychological, and motor characteristics. Understanding these distinct profiles can help tailor specific therapeutic interventions for each subgroup.
Review
Biology
Luise Schaefer, Nicola Maffulli, Alice Baroncini, Joerg Eschweiler, Frank Hildebrand, Filippo Migliorini
Summary: This study compared the efficacy of local steroid injections (LSIs) and carpal tunnel release (CTR) for the treatment of carpal tunnel syndrome (CTS). The results showed that both methods were effective and feasible, with LSIs providing better pain relief. However, this superiority was not permanent, so LSIs may be considered in patients with CTS, but CTR should be recommended.
Article
Multidisciplinary Sciences
Malin Zimmerman, Evelina Hall, Katarina Steen Carlsson, Erika Nyman, Lars B. Dahlin
Summary: The study found that patients with poorer socioeconomic status had higher QuickDASH scores at 12 months post OCTR, but these factors did not affect the relative improvement in QuickDASH.
SCIENTIFIC REPORTS
(2021)
