Topoisomerase I inhibitor, irinotecan, depletes regulatory T cells and up-regulates MHC class I and PD-L1 expression, resulting in a supra-additive antitumor effect when combined with anti-PD-L1 antibodies

Title
Topoisomerase I inhibitor, irinotecan, depletes regulatory T cells and up-regulates MHC class I and PD-L1 expression, resulting in a supra-additive antitumor effect when combined with anti-PD-L1 antibodies
Authors
Keywords
-
Journal
Oncotarget
Volume 9, Issue 59, Pages -
Publisher
Impact Journals, LLC
Online
2018-07-31
DOI
10.18632/oncotarget.25830

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