Chrysin Ameliorates Malfunction of Retinoid Visual Cycle through Blocking Activation of AGE-RAGE-ER Stress in Glucose-Stimulated Retinal Pigment Epithelial Cells and Diabetic Eyes

Role of endoplasmic reticulum stress in 12/15-lipoxygenase-induced retinal microvascular dysfunction in a mouse model of diabetic retinopathy

(2018) Khaled Elmasry et al.   DIABETOLOGIA

Pharmacotherapy of retinal disease with visual cycle modulators

(2018) Rehan M. Hussain et al.   EXPERT OPINION ON PHARMACOTHERAPY

Therapeutic potential of curcumin in major retinal pathologies

(2018) Krishi V. Peddada et al.   INTERNATIONAL OPHTHALMOLOGY

Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cells

(2017) Maria Hytti et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Pharmacological Effects of Lutein and Zeaxanthin on Visual Disorders and Cognition Diseases

(2017) Yu-Ping Jia et al.   MOLECULES

Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells

(2017) Leonid Minasyan et al.   Oxidative Medicine and Cellular Longevity

Age-related cataracts: Role of unfolded protein response, Ca 2+ mobilization, epigenetic DNA modifications, and loss of Nrf2/Keap1 dependent cytoprotection

(2017) Palsamy Periyasamy et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Neuroprotective effect of bilberry extract in a murine model of photo-stressed retina

(2017) Hideto Osada et al.   PLoS One

Placental growth factor and its potential role in diabetic retinopathy and other ocular neovascular diseases

(2016) Quan Dong Nguyen et al.   ACTA OPHTHALMOLOGICA

Insights on the involvement of (–)-epigallocatechin gallate in ER stress-mediated apoptosis in age-related macular degeneration

(2016) Bose Karthikeyan et al.   APOPTOSIS

Autophagy in Diabetic Retinopathy

(2016) Michelino Di Rosa et al.   Current Neuropharmacology

Methylglyoxal induces cell death through endoplasmic reticulum stress-associated ROS production and mitochondrial dysfunction

(2016) Chi-Ming Chan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Autophagy in the eye: Development, degeneration, and aging

(2016) Patricia Boya et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Dietary Compound Chrysin Inhibits Retinal Neovascularization with Abnormal Capillaries in db/db Mice

(2016) Min-Kyung Kang et al.   Nutrients

Diabetic retinopathy

(2016) Tien Y. Wong et al.   Nature Reviews Disease Primers

Oxidative stress, mitochondrial damage and diabetic retinopathy

(2015) Renu A. Kowluru et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The effect of baicalin in a mouse model of retinopathy of prematurity

(2015) Hyoung Jo et al.   BMB Reports

Aldose reductase inhibition alleviates hyperglycemic effects on human retinal pigment epithelial cells

(2015) Kun-Che Chang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Nonbiological pharmacotherapies for the treatment of diabetic macular edema

(2015) Aniruddha Agarwal et al.   EXPERT OPINION ON PHARMACOTHERAPY

Hyperglycemia-induced GLP-1R downregulation causes RPE cell apoptosis

(2015) Dong-Il Kim et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Chrysin inhibits diabetic renal tubulointerstitial fibrosis through blocking epithelial to mesenchymal transition

(2015) Min-Kyung Kang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Neuroprotective effects of chrysin: From chemistry to medicine

(2015) Seyed Fazel Nabavi et al.   NEUROCHEMISTRY INTERNATIONAL

Chrysin attenuates inflammation by regulating M1/M2 status via activating PPARγ

(2014) Xiujing Feng et al.   BIOCHEMICAL PHARMACOLOGY

Ocular Inflammation and Endoplasmic Reticulum Stress Are Attenuated by Supplementation with Grape Polyphenols in Human Retinal Pigmented Epithelium Cells and in C57BL/6 Mice

(2014) Jung-Heun Ha et al.   JOURNAL OF NUTRITION

Sulforaphane inhibits advanced glycation end product–induced pericyte damage by reducing expression of receptor for advanced glycation end products

(2014) Sayaka Maeda et al.   NUTRITION RESEARCH

Oxidative Stress: Implications for the Development of Diabetic Retinopathy and Antioxidant Therapeutic Perspectives

(2014) Ying Wu et al.   Oxidative Medicine and Cellular Longevity

Involvement of Endoplasmic Reticulum Stress in All-Trans-Retinal-Induced Retinal Pigment Epithelium Degeneration

(2014) Jie Li et al.   TOXICOLOGICAL SCIENCES

Advanced Glycation End Products and Diabetic Retinopathy

(2013) M. Chen et al.   CURRENT MEDICINAL CHEMISTRY

Effects of modified LDL and HDL on retinal pigment epithelial cells: a role in diabetic retinopathy?

(2013) M. Du et al.   DIABETOLOGIA

Anti-vascular endothelial growth factor therapy for diabetic macular edema

(2013) David S. Boyer et al.   Therapeutic Advances in Endocrinology and Metabolism

Key enzymes of the retinoid (visual) cycle in vertebrate retina

(2011) Philip D. Kiser et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Aldose Reductase / Polyol Inhibitors for Diabetic Retinopathy

(2011) Irina G. Obrosova et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

ER stress in retinal degeneration: a target for rational therapy?

(2011) Ana Griciuc et al.   TRENDS IN MOLECULAR MEDICINE

Retinol dehydrogenases (RDHs) in the visual cycle

(2010) Ryan O. Parker et al.   EXPERIMENTAL EYE RESEARCH

Toxicity and Intraocular Properties of a Novel Long-Acting Anti-Proliferative and Anti-Angiogenic Compound IMS2186

(2009) Iryna A. Falkenstein et al.   CURRENT EYE RESEARCH

RPE65: Role in the Visual Cycle, Human Retinal Disease, and Gene Therapy

(2009) Xue Cai et al.   OPHTHALMIC GENETICS