Scar-modulating treatments for central nervous system injury

Perivascular Fibroblasts Form the Fibrotic Scar after Contusive Spinal Cord Injury

(2013) C. Soderblom et al.   JOURNAL OF NEUROSCIENCE

Combination treatment with chondroitinase ABC in spinal cord injury—breaking the barrier

(2013) Rong-Rong Zhao et al.   Neuroscience Bulletin

The glial scar in spinal cord injury and repair

(2013) Yi-Min Yuan et al.   Neuroscience Bulletin

Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination

(2012) Lorraine W. Lau et al.   ANNALS OF NEUROLOGY

Role of the lesion scar in the response to damage and repair of the central nervous system

(2012) Hitoshi Kawano et al.   CELL AND TISSUE RESEARCH

Delayed cell cycle pathway modulation facilitates recovery after spinal cord injury

(2012) Junfang Wu et al.   CELL CYCLE

Interferon-β Delivery via Human Neural Stem Cell Abates Glial Scar Formation in Spinal Cord Injury

(2012) Yusuke Nishimura et al.   CELL TRANSPLANTATION

Lentiviral vector delivery of short hairpin RNA to NG2 and neurotrophin-3 promotes locomotor recovery in injured rat spinal cord

(2012) Eleanor M. Donnelly et al.   CYTOTHERAPY

17β-Estradiol Inhibits Apoptotic Cell Death of Oligodendrocytes by Inhibiting RhoA-JNK3 Activation after Spinal Cord Injury

(2012) Jee Y. Lee et al.   ENDOCRINOLOGY

ConditionalSox9ablation reduces chondroitin sulfate proteoglycan levels and improves motor function following spinal cord injury

(2012) William M. McKillop et al.   GLIA

Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion

(2012) Junfang Wu et al.   Journal of Neuroinflammation

PlexinA2 limits recovery from corticospinal axotomy by mediating oligodendrocyte-derived Sema6A growth inhibition

(2012) Sang-Ohk Shim et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans

(2012) Travis L Dickendesher et al.   NATURE NEUROSCIENCE

Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

(2012) Bert J C Janssen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Passive immunization with tenascin-R (TN-R) polyclonal antibody promotes axonal regeneration and functional recovery after spinal cord injury in rats

(2012) Jian You et al.   NEUROSCIENCE LETTERS

RhoA-inhibiting NSAIDs promote axonal myelination after spinal cord injury

(2011) Bin Xing et al.   EXPERIMENTAL NEUROLOGY

Myelin associated inhibitors: A link between injury-induced and experience-dependent plasticity

(2011) Feras Akbik et al.   EXPERIMENTAL NEUROLOGY

Role of myelin-associated inhibitors in axonal repair after spinal cord injury

(2011) Jae K. Lee et al.   EXPERIMENTAL NEUROLOGY

Hepatocyte growth factor reduces astrocytic scar formation and promotes axonal growth beyond glial scars after spinal cord injury

(2011) Soo Ryeong Jeong et al.   EXPERIMENTAL NEUROLOGY

High molecular weight hyaluronic acid limits astrocyte activation and scar formation after spinal cord injury

(2011) Zin Z Khaing et al.   Journal of Neural Engineering

Axonal Regrowth after Spinal Cord Injury via Chondroitinase and the Tissue Plasminogen Activator (tPA)/Plasmin System

(2011) N. Bukhari et al.   JOURNAL OF NEUROSCIENCE

Leukocyte Common Antigen-Related Phosphatase Is a Functional Receptor for Chondroitin Sulfate Proteoglycan Axon Growth Inhibitors

(2011) D. Fisher et al.   JOURNAL OF NEUROSCIENCE

Down-Regulation of Glial Fibrillary Acidic Protein and Vimentin by RNA Interference Improves Acute Urinary Dysfunction Associated with Spinal Cord Injury in Rats

(2011) Terushige Toyooka et al.   JOURNAL OF NEUROTRAUMA

EphA4 Blockers Promote Axonal Regeneration and Functional Recovery Following Spinal Cord Injury in Mice

(2011) Yona Goldshmit et al.   PLoS One

Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury

(2011) F. Hellal et al.   SCIENCE

A Pericyte Origin of Spinal Cord Scar Tissue

(2011) C. Goritz et al.   SCIENCE

EphA4 deficient mice maintain astroglial–fibrotic scar formation after spinal cord injury

(2010) Julia E. Herrmann et al.   EXPERIMENTAL NEUROLOGY

PTEN/mTOR and axon regeneration

(2010) Kevin K. Park et al.   EXPERIMENTAL NEUROLOGY

Triptolide promotes spinal cord repair by inhibiting astrogliosis and inflammation

(2010) Zhida Su et al.   GLIA

Fibrinogen Triggers Astrocyte Scar Formation by Promoting the Availability of Active TGF-  after Vascular Damage

(2010) C. Schachtrup et al.   JOURNAL OF NEUROSCIENCE

MAG and OMgp Synergize with Nogo-A to Restrict Axonal Growth and Neurological Recovery after Spinal Cord Trauma

(2010) W. B. J. Cafferty et al.   JOURNAL OF NEUROSCIENCE

Combined Genetic Attenuation of Myelin and Semaphorin-Mediated Growth Inhibition Is Insufficient to Promote Serotonergic Axon Regeneration

(2010) J. K. Lee et al.   JOURNAL OF NEUROSCIENCE

Assessing Spinal Axon Regeneration and Sprouting in Nogo-, MAG-, and OMgp-Deficient Mice

(2010) Jae K. Lee et al.   NEURON

Molecular size hyaluronan differently modulates toll-like receptor-4 in LPS-induced inflammation in mouse chondrocytes

(2009) Giuseppe M. Campo et al.   BIOCHIMIE

Expression of Transforming Growth Factor-β Receptors in Meningeal Fibroblasts of the Injured Mouse Brain

(2009) Yukari Komuta et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Inhibitors of slit protein interactions with the heparan sulphate proteoglycan glypican-1: Potential agents for the treatment of spinal cord injury

(2009) Elizabeth Lau et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Transgenic inhibition of astroglial NF-κB leads to increased axonal sparing and sprouting following spinal cord injury

(2009) Roberta Brambilla et al.   JOURNAL OF NEUROCHEMISTRY

Receptors for myelin inhibitors: Structures and therapeutic opportunities

(2009) Zixuan Cao et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The bright side of the glial scar in CNS repair

(2009) Asya Rolls et al.   NATURE REVIEWS NEUROSCIENCE

Inhibition of TGF-β1 promotes functional recovery after spinal cord injury

(2009) Masaaki Kohta et al.   NEUROSCIENCE RESEARCH

PTP  Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration

(2009) Y. Shen et al.   SCIENCE

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Endothelin-1 Regulates Astrocyte Proliferation and Reactive Gliosis via a JNK/c-Jun Signaling Pathway

(2008) A. Gadea et al.   JOURNAL OF NEUROSCIENCE

Inactivation of Glycogen Synthase Kinase 3 Promotes Axonal Growth and Recovery in the CNS

(2008) J. Dill et al.   JOURNAL OF NEUROSCIENCE

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

(2008) J. E. Herrmann et al.   JOURNAL OF NEUROSCIENCE

Regeneration of nigrostriatal dopaminergic axons after transplantation of olfactory ensheathing cells and fibroblasts prevents fibrotic scar formation at the lesion site

(2008) Xichuan Teng et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury

(2008) Gregory W. J. Hawryluk et al.   Neurosurgical Focus

PirB is a Functional Receptor for Myelin Inhibitors of Axonal Regeneration

(2008) J. K. Atwal et al.   SCIENCE

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

(2007) Michael T. Fitch et al.   EXPERIMENTAL NEUROLOGY