Review
Engineering, Mechanical
Fangfang Sun, Tianze Wang, Yong Yang
Summary: This review paper provides a comprehensive study of various types of HAp composite scaffold fabricated with RP technologies, introducing their potential applications in bone tissue engineering and discussing future research directions.
RAPID PROTOTYPING JOURNAL
(2022)
Article
Chemistry, Applied
Katherine A. Pitrolino, Reda M. Felfel, Laura Macri Pellizzeri, Jane McLaren, Alexander A. Popov, Virginie Sottile, Colin A. Scotchford, Brigitte E. Scammell, George A. F. Roberts, David M. Grant
Summary: An innovative multi-layered chitosan scaffold was developed for repairing osteochondral defects, with a distinct gradient of pore size and the addition of nanohydroxyapatite for strength. The scaffold exhibited good mechanical performance under loading, supported attachment and proliferation of human mesenchymal stem cells, and facilitated osteogenic and chondrogenic differentiation in specific layers.
CARBOHYDRATE POLYMERS
(2022)
Article
Engineering, Biomedical
Xiaohu Chen, Zuoxun Huang, Qing Yang, Xiyang Zeng, Ruqing Bai, Li Wang
Summary: This study developed a biodegradable composite porous polyurethane scaffold with responsive shape changing performance and good osteoconductivity, making it a promising candidate for implantation of bone defects.
BIOMEDICAL MATERIALS
(2022)
Article
Engineering, Biomedical
Ade Indra, Irfan Hamid, Jerry Farenza, Nofriady Handra, Adi Subardi, Adi Subardi
Summary: This study utilized green phenolic granules as a pore-forming agent for HA scaffold, achieving desired porosity and compressive strength. The scaffold showed interconnected pores at a HA:GP ratio of 55:45 wt%, suitable for cell tissue growth.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
M. Samuel Collin, Swamiappan Sasikumar
Summary: Merwinite prepared with different fuels showed variations in bioactivity and hydroxyapatite deposition, with citric acid as a fuel demonstrating the best performance in terms of bioactivity.
Article
Chemistry, Inorganic & Nuclear
A. Prihanto, S. Muryanto, R. Ismail, J. Jamari, A. P. Bayuseno
Summary: This paper investigates the synthesis of nanocrystalline hydroxyapatite (HA) through a hydrothermal autoclave reactor using various pH values and temperatures. The analysis of the synthesized powders reveals the presence of hexagonal and monoclinic HA phases, with the hexagonal phase becoming more prevalent with increasing temperature. Additionally, the study confirms the thermal stability of the hydrothermally derived HA powders and their potential for biomedical applications.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Materials Science, Ceramics
Yunzi Xin, Sohei Nakagawa, Harumitsu Nishikawa, Takashi Shirai
Summary: The study achieved complete decomposition of volatile organic compounds on HAp powder, and developed a new type of porous HAp ceramic filter with comparable catalytic performance to HAp powder. By controlling the structural features of the pores such as pore size and porosity, the catalytic performance and gas permeability of porous HAp can be adjusted. The superior catalytic activity of HAp filters without the need for noble-metal nanoparticle catalysts presents a novel strategy for future VOC decomposition techniques.
CERAMICS INTERNATIONAL
(2021)
Article
Biophysics
Gan Xu, Yao Zhao, Yusheng Geng, Shujun Cao, Panpan Pan, Jianhua Wang, Jingdi Chen
Summary: The study fabricated a continuous one-phase gradient scaffold to simulate the complex environment of different layers in natural joint. By modifying CS with SH and GO, and in situ generating nHAP with gradient distribution in the scaffold, the scaffold showed excellent bionic properties that could promote the proliferation of bone marrow mesenchymal stem cells and articular regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Engineering, Biomedical
Kai Huang, Mo-song Yang, Yu-jun Tang, Shi-Yong Ling, Feng Pan, Xiao-dong Liu, Jun Chen
Summary: The study utilized PCL-diols to prepare a porous SMP-HA scaffold with shape deformation and fixed properties, as well as good shape recovery property under body temperature. The scaffold completely degrades after 6 months post-implantation and holds great promise for bone tissue engineering applications.
JOURNAL OF BIOMATERIALS APPLICATIONS
(2021)
Article
Materials Science, Ceramics
Alessandro Schiavi, Elisa Fiume, Gissur Orlygsson, Martin Schwentenwein, Enrica Verne, Francesco Baino
Summary: In this study, the mass transport properties of hydroxyapatite (HA) scaffolds produced by digital light processing (DLP) were determined using the Ergun-Wu resistance model. The results confirmed the feasibility and practical application of the DLP-derived HA scaffolds in clinical practice.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2022)
Review
Polymer Science
Alex Lopez Marquez, Ivan Emilio Gareis, Fernando Jose Dias, Christoph Gerhard, Maria Florencia Lezcano
Summary: Electrospun scaffolds are an important research direction in tissue engineering as they can imitate the hierarchical structures of the extracellular matrix. This article discusses the issues with commonly used methods for characterizing electrospun scaffolds and proposes more suitable imaging and physical measurement methods. The results show that imaging methods have the most benefits, with limitations only in terms of cost and expertise. By using more accurate characterization methods, researchers can gain a better understanding of the characteristics of electrospun scaffolds.
Article
Materials Science, Multidisciplinary
Runbo Jiang, Zhongshu Ren, Joseph Aroh, Amir Mostafaei, Benjamin Gould, Tao Sun, Anthony D. Rollett
Summary: The competition between epitaxial and equiaxed solidification was investigated in CMSX-4 single crystal superalloy during laser melting in additive manufacturing. Single-track laser scans were performed on a powder-free surface of directionally solidified CMSX-4 alloy with various laser power and scanning velocity combinations. The results showed that the as-solidified microstructure was dominated by epitaxial grain growth with the presence of stray grains in elongated melt pools. Higher laser scanning velocity and lower power were found to help reduce the occurrence of stray grains, and a stable keyhole and minimal fluid velocity further mitigated stray grains in laser single tracks.
METALLURGICAL AND MATERIALS TRANSACTIONS A-PHYSICAL METALLURGY AND MATERIALS SCIENCE
(2023)
Article
Chemistry, Analytical
Cheng-Tang Pan, Wen-Hsin Hsu, Yu-Shun Cheng, Zhi-Hong Wen, Wen-Fan Chen
Summary: By incorporating biodegradable materials into the design of a composite bone defect scaffold, it is possible to reduce the stress shielding effect caused by excessive stiffness, optimize the scaffold structure, and improve structural stability.
Article
Materials Science, Ceramics
Angelica M. Castillo-Paz, Dorian F. Canon-Davila, Sandra M. Londono-Restrepo, Daniel Jimenez-Mendoza, Heriberto Pfeiffer, Rafael Ramirez-Bon, Mario E. Rodriguez-Garcia
Summary: This study aimed to fabricate and characterize bovine nanohydroxyapatite (nano-HAp) scaffolds at a low sintering temperature. The results showed that the macro-porosity and pore structure of the scaffolds can be controlled by manipulating the starch content, which is of great significance for the biocompatibility and application prospects of the scaffolds.
CERAMICS INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Alexander L. Danesi, Dimitra Athanasiadou, Ahmad Mansouri, Alina Phen, Mehrnoosh Neshatian, James Holcroft, Johan Bonde, Bernhard Ganss, Karina M. M. Carneiro
Summary: Biomineralization is a crucial process in which organisms produce mineralized tissues, such as teeth, bones, and shells, composed of hierarchically organized hydroxyapatite crystals. Developing protein-based materials as artificial scaffolds for guiding hydroxyapatite growth is an attractive goal for designing ordered nanomaterials and tissue regeneration. Uniaxial hydroxyapatite growth on a nanoengineered amelogenin scaffold combined with amelotin may provide insights into the molecular mechanism of hydroxyapatite formation and mineralized tissue formation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Engineering, Biomedical
Norzuria Ibrahim, Noor Azuan Abu Osman, Abdul Halim Mokhtar, Nooranida Arifin, Juliana Usman, Hanie Nadia Shasmin
Summary: Service is crucial in table tennis, and this study investigates the impact of arm segment rotations on ball impact during forehand service. The findings suggest that different rotational movements of the arm can contribute to increased racket and ball speed, providing players with better techniques for long shot and drop shot services.
SPORTS BIOMECHANICS
(2022)
Article
Automation & Control Systems
Jingjing Liu, Noor Azuan Abu Osman, Mouaz Al Kouzbary, Hamza Al Kouzbary, Nasrul Anuar Abd Razak, Hanie Nadia Shasmin, Nooranida Arifin
Summary: The paper discusses the importance of selecting and optimizing suitable elastic actuators in the design of powered ankle-foot prostheses, proposing a method to effectively reduce peak mechanical power and mean energy consumption power by optimizing with different elastic elements. The experiments found that UPEA and SE+UPEA both significantly improved in performance after optimization, recommended as the selection basis for the design of powered ankle-foot prostheses.
INTERNATIONAL JOURNAL OF CONTROL AUTOMATION AND SYSTEMS
(2022)
Review
Rehabilitation
Nur A. Hashim, Nasrul A. Abd Razak, Thilagavathi Shanmuganathan, Rafidah A. Jaladin, Hossein Gholizadeh, Noor A. Abu Osman
Summary: The study suggests that the research quality on virtual reality technology in the rehabilitation of individuals with upper limb loss is low, indicating the need for improvements in research protocols and evaluation of existing devices. Most studies have utilized inadequate design and there is a call for more rigorous randomized controlled trials.
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
(2022)
Article
Engineering, Mechanical
Aina Munirah Ab Rasid, Azlina Musa, Muhammad Amirul Abdullah, Anwar P. P. Abdul Majeed, Mohd Azraai Mohd Razmaan, Mohamad Razali Abdullah, Noor Azuan Abu Osman, Rabiu Muazu Musa
Summary: Recent advances in sports technology have allowed sports engineers to create a customised data collection system using inertial measurement units (IMUs). This study investigated the reliability of a custom-made IMU system in evaluating skateboarding manoeuvres and found that the system was reliable in measuring skateboarding tricks performances.
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART P-JOURNAL OF SPORTS ENGINEERING AND TECHNOLOGY
(2022)
Article
Multidisciplinary Sciences
Jingjing Liu, Noor Azuan Abu Osman, Mouaz Al Kouzbary, Hamza Al Kouzbary, Nasrul Anuar Abd Razak, Hanie Nadia Shasmin, Nooranida Arifin
Summary: Planar spiral springs are crucial for miniaturizing motor-based elastic actuators. However, the stiffness calculation of the spring arms using beam bending theory leads to significant errors compared to finite-element analysis (FEA) results. This study trains two Gaussian process regression models to correct this error term in the stiffness calculation of spring arms and complete springs. The models are validated through simulations and the design and manufacture of a planar spiral spring for a powered ankle-foot prosthesis.
SCIENTIFIC REPORTS
(2022)
Article
Biochemical Research Methods
Gustavo A. Orozco, Kalle Karjalainen, Eng Kuan Moo, Lauri Stenroth, Petri Tanska, Jaqueline Lourdes Rios, Teemu Tuomainen, Mikko J. Nissi, Hanna Isaksson, Walter Herzog, Rami K. Korhonen
Summary: In this study, a musculoskeletal finite element model of a rat knee joint was used to evaluate cartilage biomechanical responses during a gait cycle. The results showed that simulating anatomical and locomotion characteristics accurately estimated tissue responses such as contact pressures, stresses, strains, and fluid pressures. This approach is important for investigating the effects of gait abnormalities on the adaptation and degeneration of rat knee joint tissues and could contribute to understanding the biomechanically-driven mechanisms of osteoarthritis progression as a consequence of joint injury or obesity.
PLOS COMPUTATIONAL BIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Rabiu Muazu Musa, Isyaku Hassan, Mohamad Razali Abdullah, Mohd Nazri Latiff Azmi, Anwar P. P. Abdul Majeed, Noor Azuan Abu Osman
Summary: The non-complexity and health benefits of tennis make it popular, but increased participation has also led to more injuries. Analysis of media reports showed that elite players are more prone to injuries, with knee, hip, elbow, and shoulder being the most common areas affected. International tennis tournaments are associated with a higher risk of injuries.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Computer Science, Artificial Intelligence
Hamza Al Kouzbary, Mouaz Al Kouzbary, Lai Kuan Tham, Jingjing Liu, Hanie Nadia Shasmin, Noor Azuan Abu Osman
Summary: This study proposed a novel method for automatic adjustment to simulate intact lower limb behavior at different walking speeds and terrains. By utilizing gait data from seven healthy subjects, a neural network was trained to estimate foot orientation, achieving good estimation accuracy.
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS
(2022)
Article
Engineering, Mechanical
Mouaz Al Kouzbary, Hamza Al Kouzbary, Jingjing Liu, Taha Khamis, Zaina Al-Hashimi, Hanie Nadia Shasmin, Nooranida Arifin, Noor Azuan Abu Osman
Summary: This paper presents an initial design of a robotic knee prosthesis, utilizing BLDC motor, cycloidal gear, four-bar mechanism, and timing belt transmission. The four-bar mechanism is optimized using particle swarm optimization to achieve a maximum torque of 84 N.m. However, the current design lacks an elastic component which will be addressed in future studies.
Article
Polymer Science
Jingjing Liu, Muhammad Awais Naeem, Mouaz Al Kouzbary, Hamza Al Kouzbary, Hanie Nadia Shasmin, Nooranida Arifin, Nasrul Anuar Abd Razak, Noor Azuan Abu Osman
Summary: 3D printing is the optimal method for producing frame parts of powered ankle-foot prostheses, but the compressive strength of the 3D-printed parts must be ensured. This study investigates the impact of infill pattern and density on compressive strength, using a carbon fiber-reinforced nylon material and following ASTM D695 compression test standard. Results show that specimens with higher mass exhibit greater compressive strength, and triangular fill patterns offer higher compressive strength than rectangular and gyroid fills at the same mass. Compared to solid fill specimens, triangular fill specimens provide more compressive strength per unit mass. Based on the findings, a 41% triangular fill is chosen for manufacturing the supporting part of the powered ankle-foot prosthesis, meeting the design requirements with a strain of 1.32 +/- 0.04% under a compressive load of 1225 N. This study provides evidence for the application of 3D printing in other contexts requiring compressive strength.
Article
Multidisciplinary Sciences
Nik Abdul Muiz Nik Zainuddin, Nasrul Anuar Abd Razak, Mohd Sayuti Ab Karim, Noor Azuan Abu Osman
Summary: This study aims to determine the optimal ratio of epoxy and acrylic resin for laminated prosthetic sockets and evaluate the surface roughness of different combinations. The results show that epoxy resin produces a smoother surface compared to acrylic resin, making it a better choice for fabricating laminated sockets.
SCIENTIFIC REPORTS
(2023)
Article
Hospitality, Leisure, Sport & Tourism
Azrena Zaireen Ahmad Zahudi, Juliana Usman, Noor Azuan Abu Osman
Summary: The aim of this study was to investigate the effect of hand dimensions and selected anthropometric characteristics on handgrip strength in recreational tenpin bowlers. The results showed that body height and the minimum breadth of the right hand had a significant impact on handgrip strength. There was a significant difference in handgrip strength between males and females, with males showing greater strength.
PEDAGOGY OF PHYSICAL CULTURE AND SPORTS
(2023)
Article
Health Care Sciences & Services
Mohd Khairuddin Mohd Safee, Noor Azuan Abu Osman
Summary: This study aimed to investigate the correlation between muscle fatigue and postural stability and fall risk. The results showed a significant increase in postural stability index (OSI) after fatigue, while no significant difference was found for APSI and MLSI. Fall risk did not show significant differences, but there was an increase in mean score data after fatigue. The correlation analysis revealed a positive correlation between OSI and fall risk, and a significant negative correlation between MLSI and APSI.
HEALTHCARE IN LOW-RESOURCE SETTINGS
(2023)
Article
Computer Science, Information Systems
Khaled Nedal Mahmoud Sobh, Nasrul Anuar Abd Razak, Noor Azuan Abu Osman
Summary: The assessment of residual limb muscles in amputees is crucial for rehabilitation, and a new cuff system using force-sensitive resistor sensors has been developed to measure muscle contraction. Tightness of the cuff was identified as an issue that may affect activities during testing.
Article
Education & Educational Research
Abdul Hafaz Ngah, Nurul Izni Kamalrulzaman, Mohamad Firdaus Halimi Mohamad, Rosyati Abdul Rashid, Nor Omaima Harun, Nur Asma Ariffin, Noor Azuan Abu Osman
Summary: This study explored the factors influencing students' willingness to continue with the online learning system during the COVID-19 pandemic and found that students' e-learning readiness, performance, and satisfaction have a positive impact on their willingness.
RESEARCH AND PRACTICE IN TECHNOLOGY ENHANCED LEARNING
(2022)