Article
Clinical Neurology
Zhiqiang Li, Shuhui Wu, Fang Liang, Fengjiao Tan, Ning Li, Mengxin Bao
Summary: This study aimed to assess the outcomes and mortality rates after 90 days of endovascular thrombectomy (EVT) in young Chinese patients with acute ischemic stroke and large vessel occlusion (AIS-LVO), as well as their predictors. The study included 113 patients aged 18-50 years and found that EVT provided higher rates of arterial recanalization, but had limited effects on favorable outcomes and risk of death at 3 months. Increased NIHSS scores on admission may be associated with poor patient prognosis.
FRONTIERS IN NEUROLOGY
(2023)
Article
Clinical Neurology
Fengli Li, Hongfei Sang, Jiaxing Song, Zhangbao Guo, Shuai Liu, Weidong Luo, Junjie Yuan, Zhongming Qiu, Jiacheng Huang, Luming Chen, Linyu Li, Deping Wu, Wenjie Zi, Raul Gomes Nogueira, Jie Shuai, Qingwu Yang
Summary: This article reports the results of the BASILAR registry, which aimed to evaluate the impact of endovascular treatment and conventional treatment on the clinical outcomes of patients with acute basilar artery occlusion in China. The findings suggest that endovascular treatment is more beneficial in terms of functional outcome at one year compared to conventional treatment, and the one-year mortality rate is lower in the endovascular treatment group.
Article
Clinical Neurology
Sven P. R. Luijten, Daniel Bos, Kars C. J. Compagne, Lennard Wolff, Charles B. L. M. Majoie, Yvo B. W. E. M. Roos, Wim H. van Zwam, Robert J. van Oostenbrugge, Diederik W. J. Dippel, Aad van der Lugt, Adriaan C. G. M. van Es
Summary: The severity of white matter lesions is negatively associated with functional outcomes in patients with acute ischemic stroke, but does not modify the effect of endovascular treatment.
Article
Clinical Neurology
Dapeng Sun, Xiaochuan Huo, Raynald, Anxin Wang, Baixue Jia, Xu Tong, Gaoting Ma, Dapeng Mo, Feng Gao, Ning Ma, Zhongrong Miao
Summary: This study aimed to determine the incidence and independent predictors of the 90-day poor outcome in patients with acute vertebrobasilar artery occlusion (VBAO) after endovascular treatment (EVT). The study found that the use of general anesthesia, heparin during the procedure, admission National Institute of Health Stroke Scale (NIHSS) score, time from onset to puncture, and procedure duration were independent predictors of the 90-day poor outcome after EVT.
Article
Clinical Neurology
Peng-fei Xing, Yong-wei Zhang, Lei Zhang, Zi-fu Li, Hong-jian Shen, Yong-xin Zhang, He Li, Wei-long Hua, Pei Liu, Peng Liu, Peng-fei Yang, Bo Hong, Ben-qiang Deng, Jian-min Liu
Summary: In patients with large vessel occlusion and ASPECTS <6, a higher baseline cortical ASPECTS value was found to be a key factor associated with achieving a good clinical outcome after endovascular treatment.
Article
Neuroimaging
Wouter van der Steen, Nadinda A. M. van der Ende, Sven P. R. Luijten, Leon A. Rinkel, Katinka R. van Kranendonk, Henk van Voorst, Stefan D. Roosendaal, Ludo F. M. Beenen, Jonathan M. Coutinho, Bart J. Emmer, Robert J. van Oostenbrugge, Charles B. L. M. Majoie, Hester F. Lingsma, Aad van der Lugt, Diederik W. J. Dippel, Bob Roozenbeek
Summary: Through data analysis, it was found that ICH after endovascular treatment is associated with worse functional outcome, and both asymptomatic and symptomatic ICH are associated with worse functional outcome.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Clinical Neurology
Franny Hulscher, Yousra Farouki, Benjamin Mine, Thomas Bonnet, Maud Wang, Stephanie Elens, Juan Vazquez Suarez, Lise Jodaitis, Noemie Ligot, Gilles Naeije, Boris Lubicz, Adrien Guenego
Summary: Older age, longer puncture to recanalization time, and higher baseline core volume are associated with poorer clinical outcomes after mechanical thrombectomy for DMVO, while successful recanalization is associated with better outcomes.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Mahmoud H. Mohammaden, Diogo C. Haussen, Leonardo Pisani, Alhamza R. Al-Bayati, Nicolas Bianchi, Bernardo Liberato, Nirav Bhatt, Michael R. Frankel, Raul G. Nogueira
Summary: This study aimed to investigate whether racial background influences the outcome of mechanical thrombectomy in the elderly population. The study found that there was no racial difference in terms of outcome after mechanical thrombectomy in elderly patients.
Article
Clinical Neurology
Natalie E. Lecouffe, Kilian M. Treurniet, Manon Kappelhof, Ivo G. H. Jansen, Merel Boers, Henk A. Marquering, Ludo F. M. Beenen, Jelis Boiten, Wim H. van Zwam, Lonneke S. F. Yo, Charles B. L. M. Majoie, Yvo B. W. E. M. Roos, Bart J. Emmer, Jonathan M. Coutinho
Summary: This study aimed to investigate the implications of multivessel occlusions (MVOs) in large vessel occlusion (LVO) stroke patients undergoing endovascular treatment (EVT). The results showed that MVOs were associated with poor functional outcome and higher mortality rate.
EUROPEAN STROKE JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Sanne J. den Hartog, Osama Zaidat, Bob Roozenbeek, Adriaan C. G. M. van Es, Agnetha A. E. Bruggeman, Bart J. Emmer, Charles B. L. M. Majoie, Wim H. van Zwam, Ido R. van den Wijngaard, Pieter Jan van Doormaal, Hester F. Lingsma, James F. Burke, Diederik W. J. Dippel
Summary: The study found that first-pass reperfusion is associated with favorable outcomes in stroke treatment, independently of patient characteristics. Compared with multiple-pass reperfusion, first-pass reperfusion has better results.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Clinical Neurology
Marie Louise E. Bernsen, Frans Kauw, Jasper M. Martens, Aad van der Lugt, Lonneke S. F. Yo, Marianne A. A. van Walderveen, Yvo B. W. E. M. Roos, H. Bart van der Worp, Jan W. Dankbaar, Jeannette Hofmeijer
Summary: The study found that the incidence of malignant infarction after endovascular treatment is around 6%. Successful reperfusion decreases the risk. Independent predictors include age, NIHSS score, ASPECTS score, collateral status, and others.
INTERNATIONAL JOURNAL OF STROKE
(2022)
Article
Neuroimaging
Gang Deng, Jun Xiao, Haihan Yu, Man Chen, Ke Shang, Chuan Qin, Dai-Shi Tian
Summary: This study identified female sex, comorbidities, admission systolic blood pressure, serum glucose, occlusion site, non-bridging therapy, and post-procedural complication as predictors of futile recanalization, and also confirmed previously reported factors. Further large-scale prospective studies are needed.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Clinical Neurology
Leon A. Rinkel, Kilian M. Treurniet, Daan Nieboer, Manon Kappelhof, Natalie E. LeCouffe, Agnetha A. E. Bruggeman, Wim H. van Zwam, Geert J. Lycklama a Nijeholt, Elyas Ghariq, Maarten Uyttenboogaart, Diederik W. J. Dippel, Yvo B. W. E. M. Roos, Jonathan M. Coutinho, Charles B. L. M. Majoie, Bart J. Emmer
Summary: This study aimed to evaluate the effect of intravenous alteplase treatment (IVT) on endovascular treatment (EVT) and found that the first-line EVT technique can modify the treatment effect of IVT. Patients treated with aspiration alone as the first-line technique had worse clinical outcomes if they did not receive IVT, while no such difference was observed in patients treated with stent retrievers.
Article
Clinical Neurology
Julien Allard, Francois Delvoye, Raoul Pop, Julien Labreuche, Benjamin Maier, Gaultier Marnat, Igor Sibon, Francois Zhu, Bertrand Lapergue, Arturo Consoli, Laurent Spelle, Christian Denier, Sebastien Richard, Michel Piotin, Benjamin Gory, Mikael Mazighi
Summary: This study investigated the occurrence of stent occlusion after acute carotid artery stenting and its impact on patients. The results showed that 20.9% of patients experienced stent occlusion within a short period of time, which was associated with worse functional outcome. Stroke etiology, administration of P2Y(12) antagonists, quality of intracranial reperfusion, and angioplasty were associated with stent patency at 24 hours.
Article
Neurosciences
Chengfang Liu, Yuqiao Zhang, Xiaohui Li, Yukai Liu, Teng Jiang, Meng Wang, Qiwen Deng, Junshan Zhou
Summary: This study investigated the relationship between fasting blood glucose (FBG), glycosylated hemoglobin (HbA(1c)), and functional outcome in ischemic stroke patients who underwent endovascular treatment (EVT). The results showed that FBG, chronic glycemia, and the difference between FBG and chronic glycemia were associated with poor outcome. A glycemia-based nomogram was established and showed favorable clinical utility for predicting prognosis in EVT-treated stroke patients.
