Article
Neurosciences
Saloni Krishnan, Salomi S. Asaridou, Gabriel J. Cler, Harriet J. Smith, Hannah E. Willis, Mairead P. Healy, Paul A. Thompson, Dorothy V. M. Bishop, Kate E. Watkins
Summary: The study found that children with developmental language disorder (DLD) did not show reduced brain activity in language relevant regions compared to typically developing children when performing a simple language task. Differences in activity in the left inferior frontal gyrus and caudate nuclei were only observed in a sub-group of DLD children with the poorest performance.
Article
Psychology, Multidisciplinary
Huilin Dai, Xiaowei He, Lijun Chen, Chan Yin
Summary: This study investigated the similarities and differences in the production of Chinese negative sentences by children with DLD and children with HFA-LI. The results showed that both groups faced similar difficulties in language expression, particularly in feature agreement. However, slight differences were also detected between the two groups.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychology, Developmental
Alexander Acosta, Edward Khokhlovich, Helena Reis, Andrey Vyshedskiy
Summary: The research aimed to investigate the impact of dietary factors on developmental trajectories in young autistic children. A gluten-free and casein-free diets, as well as six types of food, were observed in 5,553 children aged 2 to 5 years. The results showed that consumption of fast-acting carbohydrates was associated with a decline in health, while a gluten-free diet and consumption of meat, eggs, and vegetables were associated with improvements in language comprehension and sensory awareness. These findings suggest potential dietary interventions for young autistic children.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Nutrition & Dietetics
Zijun Liao, Jing Wang, Fangfang Chen, Yiren Chen, Ting Zhang, Gongshu Liu, Xianghui Xie, Jun Tai
Summary: This study found that cesarean delivery may increase the risk of overweight and obesity in preschool children, and also lead to an increase in their fat mass, while fat-free mass does not significantly change.
Article
Biochemistry & Molecular Biology
Jacob W. Vogel, Alexandra L. Young, Neil P. Oxtoby, Ruben Smith, Rik Ossenkoppele, Olof T. Strandberg, Renaud La Joie, Leon M. Aksman, Michel J. Grothe, Yasser Iturria-Medina, Michael J. Pontecorvo, Michael D. Devous, Gil D. Rabinovici, Daniel C. Alexander, Chul Hyoung Lyoo, Alan C. Evans, Oskar Hansson
Summary: By using an unbiased subtyping algorithm, the study systematically characterized longitudinal tau variability in human Alzheimer's disease, identifying four trajectories of tau deposition with distinct clinical features. The results suggest that variation in tau pathology is common and systematic, potentially necessitating a re-examination of the notion of 'typical AD' and a revisiting of tau pathological staging.
Article
Clinical Neurology
Jessica W. W. Lo, John Crawford, David Desmond, Hee-Joon Bae, Jae-Sung Lim, Olivier Godefroy, Martine Roussel, Sebastian Koehler, Julie Staals, Frans Verhey, Christopher Chen, Xin Xu, Eddie J. Chong, Nagaendran Kandiah, Regis Bordet, Thibaut Dondaine, Anne-Marie Mendyk, Henry Brodaty, Latchezar Traykov, Shima M. Mehrabian, Neli Petrova, Darren S. Lipnicki, Ben Chun Pan Lam, Perminder Sachdev
Summary: This project used latent class growth analysis (LCGA) to identify patterns of cognitive trajectories after stroke. It found 3 trajectory groups based on cognition scores, which were the low-performance, medium-performance, and high-performance groups. Risk factors for the low-performance group include age, education, diabetes, large artery strokes, and stroke severity.
Article
Multidisciplinary Sciences
Shams Dakhil, Ingvild Saltvedt, Jurate Saltyte Benth, Pernille Thingstad, Leiv Otto Watne, Torgeir Bruun Wyller, Jorunn L. L. Helbostad, Frede Frihagen, Lars Gunnar Johnsen, Kristin Taraldsen
Summary: This study used data from two large randomized controlled trials to identify different trajectories of functional recovery after hip fracture and determine predictors for belonging to these groups. The study found that none of the groups were able to fully regain their pre-fracture functional levels.
Article
Biology
Saloni Krishnan, Gabriel J. Cler, Harriet J. Smith, Hanna E. Willis, Salomi S. Asaridou, Mairead P. Healy, Daniel Papp, Kate E. Watkins
Summary: This study used a novel imaging protocol to investigate microstructural neural differences in children with DLD, revealing lower MTsat values in certain brain regions and globally lower R1 values in DLD children, suggesting the presence of microstructural abnormalities.
Article
Psychology, Multidisciplinary
Haiyan Wang, Haopeng Yu
Summary: The study found that children with SLI performed worse in the production of relative clauses compared to their typically developing peers, and they were more inclined to using simple sentences and omitting complementizer as avoidance strategies.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Clinical Neurology
Tomoko Nishimura, Nagahide Takahashi, Akemi Okumura, Taeko Harada, Toshiki Iwabuchi, Chikako Nakayasu, Mohammad Shafiur Rahman, Satoshi Uchiyama, Manabu Wakuta, Yoko Nomura, Nori Takei, Atsushi Senju, Kenji J. Tsuchiya
Summary: This study aimed to explore early manifestations of autism spectrum disorders (ASD) in females and investigate sex differences in cognitive and motor functions and adaptive behaviors. The results showed that males with high autistic traits experienced a temporary decline in expressive language around the age of 2 years, while females in the high-autistic-trait group showed a downward trend in the adaptive behavior communication domain after 3.5 years. These findings suggest that females and males with higher autistic traits may have different phenotypes in certain neurodevelopmental domains during infancy and early childhood.
PSYCHIATRY AND CLINICAL NEUROSCIENCES
(2023)
Article
Behavioral Sciences
Clare Harrop, Kyle Sterrett, Wendy Shih, Rebecca Landa, Ann Kaiser, Connie Kasari
Summary: Approximately one-third of children with autism spectrum disorder (ASD) remain minimally verbal at the time of school entry. In this study, we sought to characterize the presence of restricted and repetitive behaviors (RRBs) in school-aged children (5-8) who were minimally verbal. Compared to prior studies, minimally verbal children with ASD had higher frequencies of RRBs and demonstrated a different profile of behaviors, including more verbal RRBs.
Article
Nutrition & Dietetics
Rym El Rafei, Pierre Henri Jarreau, Mikael Norman, Rolf Felix Maier, Henrique Barros, Patrick Van Reempts, Pernille Pedersen, Marina Cuttini, Raquel Costa, Michael Zemlin, Elizabeth S. Draper, Jennifer Zeitlin
Summary: Severe EUGR is associated with neurodevelopmental impairment in a very preterm birth cohort, with a significant interaction with sex. Boys have a higher risk, while girls have lower risk.
CLINICAL NUTRITION
(2021)
Article
Clinical Neurology
Xiaofeng Xu, E. Scott Huebner, Lili Tian
Summary: This study investigates the direct and indirect relations among developmental trajectories of mother-child cohesion, friendship quality, and depressive symptoms in children. The findings reveal a negative direct association between the developmental trajectories of mother-child cohesion and friendship quality, and children's depressive symptoms. Moreover, friendship quality indirectly influences the developmental trajectory of depressive symptoms through the mediating role of mother-child cohesion.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Behavioral Sciences
Grace Pulliam, Jacob I. Feldman, Tiffany G. Woynaroski
Summary: This study systematically reviewed and synthesized the literature on audiovisual multisensory integration in individuals with reading and language impairments, finding differences in sensory function between these individuals and comparisons. However, there was a small and nonsignificant correlation between audiovisual integration and reading or language ability.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Psychology, Multidisciplinary
Mari Aguilera, Nadia Ahufinger, Nuria Esteve-Gibert, Laura Ferinu, Llorenc Andreu, Monica Sanz-Torrent
Summary: The study aims to deepen our understanding of emotional regulation in children and adolescents with Developmental Language Disorder, and explore the impact of parental emotional regulation on their children's emotional regulation. Results show that expressive vocabulary predicts emotional regulation in school-age children, and parental emotional regulation affects children's emotional regulation.
FRONTIERS IN PSYCHOLOGY
(2021)