Article
Engineering, Biomedical
Jean-Francois Roulet, Mario Alexandre Coelho Sinhoreti, Stefany Pontes, Mateus Garcia Rocha
Summary: This study compared the performance of dental zirconium oxide ceramics produced using different manufacturing methods through fatigue testing and wear simulation. The results showed that ceramics produced with the high isostatic pressure (HIP) method had higher fatigue strength, and all ceramics showed no measurable wear. However, the ceramics caused some wear on the leucite reinforced glass ceramic antagonists.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Materials Science, Ceramics
Qixuan He, Yanping Qin, Xiaozhen Zhan, Wenmin Zhang, Jiandong Ye
Summary: In this study, Y-TZP ceramics infiltrated with different bioactive glasses (BGs) were successfully prepared. The modified Y-TZP/BG samples showed excellent bioactivity, with superior protein adsorption ability and sustained release of osteogenic-related ions. Cells cultured on the surface of the samples exhibited better adhesion, spreading, viability, proliferation, and osteogenic differentiation. Y-TZP ceramics infiltrated with BGs have great potential for dental implant applications.
CERAMICS INTERNATIONAL
(2023)
Article
Materials Science, Ceramics
Ke Li, Jiancun Rao, Congqin Ning
Summary: The novel dental ceramics using LDGC as an additive for Y-TZP ceramics can be fabricated at lower temperatures, showing improved densification, strength, and translucency. However, the addition of LDGC may induce structural changes in the zirconia grains.
JOURNAL OF ADVANCED CERAMICS
(2021)
Article
Materials Science, Ceramics
Clara G. Soubelet, Maria P. Albano
Summary: The study investigated the effects of adding different contents of refractory bioglass on Y-TZP and Al2O3-doped Y-TZP bioceramics, with distinct findings between YZ and AYZ. With increasing glass content, fracture toughness slightly increased for YZ but decreased for AYZ.
INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
(2021)
Article
Engineering, Biomedical
Qixuan He, Wenmin Zhang, Xiaozhen Zhan, Yanping Qin, Jiandong Ye
Summary: In this study, Y-TZP ceramics were prepared using 77S bioactive glass (BG) sol and akermanite (AKT) sol infiltration and microwave sintering, which improved its bioactivity and maintained resistance to hydrothermal aging. The results showed that the modified Y-TZP specimens had little or no tetragonal-to-monoclinic transformation and maintained relatively high mechanical properties after accelerated hydrothermal aging treatment. In vitro biological behavior tests demonstrated that the introduction of 77S BG and AKT significantly promoted cell adhesion, spreading, viability, and proliferation on the surface of modified Y-TZP ceramics. Therefore, this modification method effectively enhances the bioactivity and hydrothermal aging resistance of Y-TZP ceramics for dental implant materials application.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2023)
Article
Materials Science, Ceramics
Kohta Nambu, Taisuke Kitaoka, Koji Morita, Kohei Soga, Tomoharu Tokunaga, Takahisa Yamamoto, Hiroshi Masuda, Hidehiro Yoshida
Summary: In this study, flash joining experiments were conducted using an AC field on 3 mol% Y2O3-stabilized tetragonal ZrO2 polycrystal (Y-TZP) bodies. The necessary conditions for achieving almost complete self-joining of Y-TZP bodies were clarified. By applying an AC field at specific conditions, successful joining with 92% of the flexural strength of the as-sintered Y-TZP body was achieved.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2023)
Article
Engineering, Chemical
Vinicius Aneas Rodrigues, Thais Cachute Paradella, Arianne Valim Pinto Coelho, Karina Barbosa Souza, Marco Antonio Bottino, Renata Marques de Melo, Mutlu Ozcan, Rodrigo Othavio Assuncao e Souza
Summary: The study aimed to verify the impact of glaze application on the shear bond strength between Y-TZP and veneering ceramic, and found that within the scope of the study, glazing application did not improve the bond strength to pressed veneering ceramic.
JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Shu Zhang, Yuxin Ma, Dong Li, Changyu Liu, Ruitong Yang
Summary: In this study, an innovative reversible multiple-glazing roof integrated with two phase change materials (PCMs) and low-emissivity (low-e) glass was proposed. The thermal performance of the new roof was examined and compared with a traditional air-filled multiple-glazing roof in a cold climate. The results showed that the new glazed roof exhibited excellent thermal performance in both summer and winter, with significant energy savings and economic feasibility.
Article
Materials Science, Multidisciplinary
Nathalia C. Ramos, Larissa M. M. Alves, Gabriela F. Ramos, Marco Antonio Bottino, Renata M. Melo, Rodrigo Othavio A. Souza
Summary: The study evaluated the influence of convergence angle of tooth preparations and abutments height, as well as several surface treatments on zirconia copings through a tensile retention test. The results showed that convergence angle significantly affected the retention force, while abutments height did not show a statistically significant difference. MDP-primer and silica blasting demonstrated higher retention forces in specimens with height variations, suggesting their potential use in enhancing restoration longevity.
Article
Materials Science, Characterization & Testing
G. A. Gogotsi, V. Y. Galenko, G. de Souza
Summary: In the study of dental Y-TZP zirconia ceramics, the fracture behavior was compared with technical ceramics using the Rockwell edge chipping method, revealing no significant differences in fracture resistance values when tested with indentors of identical tip radii. This indicates that the fracture resistance of dental and technical ceramics may not show marked distinctions under certain testing conditions.
STRENGTH OF MATERIALS
(2021)
Article
Materials Science, Ceramics
Fernando Rodriguez-Rojas, Rafael Cano-Crespo, Oscar Borrero-Lopez, Arturo Dominguez-Rodriguez, Angel L. Ortiz
Summary: The study found that the dimensionality of carbon-based nano-reinforcements and testing conditions have a significant impact on the microstructural design of ceramic composites for tribological applications. Specifically, 3Y-TZP/rGO exhibited superior wear resistance compared to other materials, and wear resistance was found to be correlated with the formation of self-lubricating tribofilms rather than hardness or toughness.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2021)
Article
Materials Science, Ceramics
Ranulfo Benedito de Paula Miranda, Valter Ussui, Dolores Ribeiro Ricci Lazar, Nelson Batista de Lima, Juliana Marchi, Paulo Francisco Cesar
Summary: This study evaluated the effects of different sintering conditions on the microstructure, density, optical properties, and flexural strength of a 3Y-TZP/TiO2 dental ceramic. It was found that sintering the ceramic at 1460 degrees C for 2 hours increased the grain size and significantly decreased the flexural strength. The interaction between titania content and sintering conditions affected the relative density and optical properties. The material developed with 12.5 mol% titania and sintered at 1300 degrees C for 2 hours showed high densification and flexural strength of 670 MPa, making it a potential choice for dentistry.
CERAMICS INTERNATIONAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Felicitas Mayinger, Ramona Buser, Maximilian Laier, Lisa Marie Schonhoff, Matthias Kelch, Rudiger Hampe, Bogna Stawarczyk
Summary: This study investigated the effect of material and sintering protocol, layer thickness, and aging on the two-body wear and fracture load of 4Y-TZP crowns. The results showed that high-speed sintered crowns with a minimum thickness of 1.0 mm had sufficient mechanical properties to withstand masticatory forces, even after a simulated aging period of 5 years.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Materials Science, Ceramics
Sophie Cailliet, Marilyne Roumanie, Celine Croutxe-Barghorn, Guillaume Bernard-Granger, Richard Laucournet
Summary: Y-TZP, Ce-TZP, and Ce-TZP/Al2O3 materials are widely studied in dentistry. High loading photocurable formulations suitable for DLP printing were achieved in this study by using specific properties of the materials. The ceramics exhibit suitable curing behavior for DLP process, with Y-TZP formulations having a high conversion rate and ceria ceramic formulations having a specific UV absorption behavior for quick curing.
CERAMICS INTERNATIONAL
(2021)
Article
Chemistry, Physical
Liliya Vladislavova, Tomasz Smolorz, Nina Orlovskaya, Mykola Lugovy, Michael J. Reece, Stefan Koebel, Agnieszka Kopia, Malgorzata Makowska, Thomas Graule, Gurdial Blugan
Summary: This study examined the mechanical properties of ceramics with different grain sizes, showing that only linear elastic deformation occurs under high stress, ruling out domain switching in zirconia under the loading conditions studied.
Article
Dentistry, Oral Surgery & Medicine
Caroline de F. Charamba, James Needy, Peter S. Ungar, Frederico B. de Sousa, George J. Eckert, Anderson T. Hara
Summary: The study found that toothbrushes of higher and medium stiffness caused more tooth loss under high abrasive conditions compared to soft brushes. Variations in slurry abrasivity led to differences in tooth loss. The use of a 3D intraoral scanner could detect and monitor the progression of NCCLs, although its ability was limited for incipient lesions.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Mireille Kanaan, Alain Brabant, Anderson T. Hara, Joana C. Carvalho
Summary: This study assessed the current concepts and strategies utilized by dentists for tooth wear diagnosis, risk assessment, and treatment decisions. The results showed that Belgian dentists performed well in diagnosis and risk assessment, but there is room for improvement in treatment decisions.
EUROPEAN JOURNAL OF ORAL SCIENCES
(2021)
Review
Materials Science, Multidisciplinary
Zeynep Aytac, Nileshkumar Dubey, Arwa Daghrery, Jessica A. Ferreira, Isaac J. de Souza Araujo, Miguel Castilho, Jos Malda, Marco C. Bottino
Summary: This paper provides a detailed analysis of scaffold strategies for craniomaxillofacial bone and periodontal regeneration, focusing on the latest 3D printing technologies. The future direction discussed includes the utilization of complementary biomaterials and fabrication technologies for effective translation of personalized and functional scaffolds into clinical applications.
INTERNATIONAL MATERIALS REVIEWS
(2022)
Review
Engineering, Biomedical
Arwa Daghrery, Isaac J. de Souza Araujo, Miguel Castilho, Jos Malda, Marco C. Bottino
Summary: For almost three decades, tissue engineering strategies have been used to create effective therapies for dental, oral, and craniofacial regenerative medicine by treating permanent deformities caused by debilitating health conditions. Additive manufacturing techniques, such as melt electrowriting (MEW), enable the creation of personalized scaffolds that can replicate native tissue characteristics using 3D printing technology. Recent advancements have shown that combining MEW with other biofabrication techniques can overcome some limitations and offer promising opportunities for tissue regeneration.
ACTA BIOMATERIALIA
(2023)
Article
Dentistry, Oral Surgery & Medicine
Juliana Silva Ribeiro, Ester Alves Ferreira Bordini, Gabriel Kalil Rocha Pereira, Rohitha Rao Polasani, Cristiane Helena Squarize, Karla Zanini Kantorski, Luiz Felipe Valandro, Marco Cicero Bottino
Summary: Coating denture base material with cinnamon-laden nanofibers effectively reduces Candida albicans adhesion and proliferation, inhibiting fungal growth. Applying 20 wt.% cinnamon-laden nanofibers leads to a significant reduction in the growth of C. albicans while maintaining the viability of epithelial cells.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Biochemistry & Molecular Biology
Juliana S. Ribeiro, Eliseu A. Muenchow, Ester A. F. Bordini, Nathalie S. Rodrigues, Nileshkumar Dubey, Hajime Sasaki, John C. Fenno, Steven Schwendeman, Marco C. Bottino
Summary: This study engineered cytocompatible and injectable antibiotic-laden fibrous microparticles GelMA hydrogels for endodontic infection ablation. The modified GelMA with antibiotic-laden fibrous microparticles increased the hydrogel swelling ratio and degradation rate, while exhibiting low toxicity to cells and effective antibiofilm effects against bacteria. Overall, these engineered hydrogels show promising prospects for clinical treatment of endodontic infections.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Dentistry, Oral Surgery & Medicine
Ana C. Botta, Marco C. Bottino, Cherae M. Farmer-Dixon, Bridget M. Ferguson, M. Natalia Garcia, Susie P. Goolsby, Paul Subar
JOURNAL OF DENTAL EDUCATION
(2022)
Article
Dentistry, Oral Surgery & Medicine
N. Karl Haden, Kathryn P. Bell, Marco C. Bottino, Colin M. Haley, Karin K. Quick, Pamela C. Yelick
Summary: The purpose of the papers is to explore alternative futures for dental education, with five different scenarios developed to assist leaders and institutions in anticipating different futures and making decisions to create desirable outcomes.
JOURNAL OF DENTAL EDUCATION
(2022)
Article
Dentistry, Oral Surgery & Medicine
Margaret Anderson, Nileshkumar Dubey, Kath Bogie, Chen Cao, Junying Li, Joseph Lerchbacker, Gustavo Mendonca, Frederic Kauffmann, Marco C. Bottino, Darnell Kaigler
Summary: This study aimed to devise a protocol for fabricating customized clinical scale and patient-specific bioceramic scaffolds for reconstructing large alveolar bone defects. The study successfully developed a clinically feasible laboratory workflow using CBCT imaging to design and 3D print defect-specific bioceramic scaffolds. OsteoinkTM was identified as a biocompatible material for precision-fit alveolar bone reconstructive procedures.
Article
Dentistry, Oral Surgery & Medicine
Kiara Serafini Dapieve, Gabriel Kalil Rocha Pereira, Andressa Borin Venturini, Natalia Daudt, Andre Valcanaia, Marco Cicero Bottino, Luiz Felipe Valandro
Summary: This study assessed the effects of resin cement viscosity and surface treatment on the fatigue performance of lithium disilicate glass-ceramic crowns. The results showed that using high viscosity resin cement with HF and silane treatment, or low viscosity resin cement with E&P treatment, yielded the best fatigue performance.
Review
Dentistry, Oral Surgery & Medicine
Alexandre H. dos Reis-Prado, Lucas G. Abreu, Rogeria R. Fagundes, Sabrina de C. Oliveira, Marco C. Bottino, Antonio P. Ribeiro-Sobrinho, Francine Benetti
Summary: EDTA treatment of dentin in regenerative endodontic procedures has been found to positively influence the release of growth factors, cell migration, attachment, and differentiation. However, more research is needed to evaluate its effect on tissue regeneration, especially in animal studies where the methodological quality is low.
INTERNATIONAL ENDODONTIC JOURNAL
(2022)
Article
Dentistry, Oral Surgery & Medicine
Isaac J. de Souza Araujo, Tamannaben Patel, Amal Bukhari, Carolina K. Sanz, J. Christopher Fenno, Juliana S. Ribeiro, Marco C. Bottino
Summary: This investigation synthesized poly(d,l-lactide) (PLA)-based fibrous scaffolds containing natural essential oils and evaluated their antimicrobial properties and cytocompatibility for regenerative endodontics. The results showed that the incorporation of natural monoterpenes did not affect the scaffold's fibrous morphology and demonstrated significant antimicrobial activity against endodontic pathogens, while maintaining cell viability.
Article
Biochemistry & Molecular Biology
Afzan A. Ayoub, Abdel H. Mahmoud, Juliana S. Ribeiro, Arwa Daghrery, Jinping Xu, J. Christopher Fenno, Anna Schwendeman, Hajime Sasaki, Renan Dal-Fabbro, Marco C. Bottino
Summary: This study successfully engineered photocrosslinkable gelatin methacryloyl fibers loaded with azithromycin as a localized and biodegradable drug delivery system for endodontic infection control. The results showed that the fibers with 15% azithromycin exhibited the highest antimicrobial activity, and the addition of azithromycin reduced the mechanical properties and degradation rate of the fibers. The in vitro compatibility with cells and in vivo inflammatory response experiments also demonstrated the good biocompatibility of the fibers.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Engineering, Biomedical
Arwa Daghrery, Jessica A. Ferreira, Jinping Xu, Nasim Golafshan, Darnell Kaigler, Sarit B. Bhaduri, Jos Malda, Miguel Castilho, Marco C. Bottino
Summary: This study engineered scaffolds with specific fiber morphology and structures to guide the differentiation of periodontal ligament stem cells and mediate macrophage polarization. The results showed that aligned fiber scaffolds can promote the formation of periodontal ligament, while fluorinated calcium phosphate-coated fibers with specific strand spacings can enhance bone tissue regeneration.
BIOACTIVE MATERIALS
(2023)
Article
Engineering, Biomedical
Priscila T. A. Toledo, Caroline Anselmi, Renan Dal-Fabbro, Abdel H. Mahmoud, Alexandra K. Abel, Matthew L. Becker, Alberto C. B. Delbem, Marco C. Bottino
Summary: The aim of this study was to create and evaluate biodegradable polymer-based nanofibers incorporating different concentrations of calcium trimetaphosphate (Ca-TMP) for periodontal tissue engineering. The fibers were fabricated using electrospinning technique and characterized using various techniques. The addition of Ca-TMP improved the degradation stability and dimensional stability of the fibers without compromising their mechanical properties. Although Ca-TMP extracts enhanced cell viability and alkaline phosphatase activity, there was no significant difference between the scaffold groups in terms of cell function.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)