Evaluation on the Drug–Polymer Mixing Status in Amorphous Solid Dispersions at the Early Stage Formulation and Process Development

Title
Evaluation on the Drug–Polymer Mixing Status in Amorphous Solid Dispersions at the Early Stage Formulation and Process Development
Authors
Keywords
Amorphous solid dispersion, Physical stability, Drug–polymer mixing, Homogeneity, NIR chemical imaging (NIR CI), Principal component analysis (PCA), Transmission electron microscopy (TEM), Energy-dispersive X-ray spectroscopy (EDS), Powder X-ray diffraction (PXRD), Differential scanning calorimetry (DSC)
Journal
Journal of Pharmaceutical Innovation
Volume 8, Issue 3, Pages 163-174
Publisher
Springer Nature
Online
2013-06-21
DOI
10.1007/s12247-013-9156-z

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