The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

RNF43 Inhibits Cancer Cell Proliferation and Could be a Potential Prognostic Factor for Human Gastric Carcinoma

(2015) Lei Niu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Porcupine inhibitor suppresses paracrine Wnt-driven growth ofRnf43;Znrf3-mutant neoplasia

(2015) Bon-Kyoung Koo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ZNRF3/RNF43 – A direct linkage of extracellular recognition and E3 ligase activity to modulate cell surface signalling

(2015) Matthias Zebisch et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

The nucleoprotein of influenza A virus induces p53 signaling and apoptosis via attenuation of host ubiquitin ligase RNF43

(2015) H Nailwal et al.   Cell Death & Disease

Clinicopathological significance of somatic RNF43 mutation and aberrant expression of ring finger protein 43 in intraductal papillary mucinous neoplasms of the pancreas

(2014) Hitomi Sakamoto et al.   MODERN PATHOLOGY

Identification of Two Wnt-Responsive Elements in the Intron of RING Finger Protein 43 (RNF43) Gene

(2014) Norihiko Takahashi et al.   PLoS One

Germline Mutations in Oncogene-Induced Senescence Pathways Are Associated With Multiple Sessile Serrated Adenomas

(2013) Manish K. Gala et al.   GASTROENTEROLOGY

Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma

(2013) X. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrative Marker Analysis Allows Risk Assessment for Metastasis in Stage II Colon Cancer

(2012) Ulrich Nitsche et al.   ANNALS OF SURGERY

A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

(2012) Martijn S Luijsterburg et al.   EMBO JOURNAL

RNF43is a tumour suppressor gene mutated in mucinous tumours of the ovary

(2012) Georgina L Ryland et al.   JOURNAL OF PATHOLOGY

Reversing Effect of Ring Finger Protein 43 Inhibition on Malignant Phenotypes of human Hepatocellular Carcinoma

(2012) C. Xing et al.   MOLECULAR CANCER THERAPEUTICS

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

(2012) Huai-Xiang Hao et al.   NATURE

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

(2012) Bon-Kyoung Koo et al.   NATURE

Exome sequencing of liver fluke–associated cholangiocarcinoma

(2012) Choon Kiat Ong et al.   NATURE GENETICS

Specific activity of cyclin-dependent kinase I is a new potential predictor of tumour recurrence in stage II colon cancer

(2011) E C M Zeestraten et al.   BRITISH JOURNAL OF CANCER

Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling

(2011) Lenka Doubravska et al.   CELLULAR SIGNALLING

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

(2011) J. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas

(2011) Toru Furukawa et al.   Scientific Reports

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Generalized Maximally Selected Statistics

(2008) Torsten Hothorn et al.   BIOMETRICS

A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95

(2008) Takeyuki Sugiura et al.   EXPERIMENTAL CELL RESEARCH

Regulation of Wnt Signaling by the Nuclear Pore Complex

(2008) Miki Shitashige et al.   GASTROENTEROLOGY

Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells

(2008) P. Hatzis et al.   MOLECULAR AND CELLULAR BIOLOGY

Proteomic identification of a PSF/p54nrb heterodimer as RNF43 oncoprotein-interacting proteins

(2008) Kentaro Miyamoto et al.   PROTEOMICS