Gliptin and GLP‐1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide‐induced endotoxemia

Inhibition of AMP-Activated Protein Kinase Accentuates Lipopolysaccharide-Induced Lung Endothelial Barrier Dysfunction and Lung Injury in Vivo

(2013) Junjie Xing et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular Mechanisms of the Crosstalk Between Mitochondria and NADPH Oxidase Through Reactive Oxygen Species—Studies in White Blood Cells and in Animal Models

(2013) Swenja Kröller-Schön et al.   ANTIOXIDANTS & REDOX SIGNALING

Uncoupling Protein-2 Mediates DPP-4 Inhibitor-Induced Restoration of Endothelial Function in Hypertension Through Reducing Oxidative Stress

(2013) Limei Liu et al.   ANTIOXIDANTS & REDOX SIGNALING

Glucagon-like peptide-1 (GLP-1) and its split products GLP-1(9-37) and GLP-1(28-37) stabilize atherosclerotic lesions in apoe−/− mice

(2013) Mathias Burgmaier et al.   ATHEROSCLEROSIS

Impaired mitochondrial biogenesis due to dysfunctional adiponectin-AMPK-PGC-1α signaling contributing to increased vulnerability in diabetic heart

(2013) Wenjun Yan et al.   BASIC RESEARCH IN CARDIOLOGY

Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis

(2013) Veerle Matheeussen et al.   BASIC RESEARCH IN CARDIOLOGY

Impaired cardiometabolic responses to glucagon-like peptide 1 in obesity and type 2 diabetes mellitus

(2013) Steven P. Moberly et al.   BASIC RESEARCH IN CARDIOLOGY

CD40L contributes to angiotensin II-induced pro-thrombotic state, vascular inflammation, oxidative stress and endothelial dysfunction

(2013) Michael Hausding et al.   BASIC RESEARCH IN CARDIOLOGY

A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site

(2013) Mika Nabeno et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Contribution of Dipeptidyl Peptidase IV to the Severity of Dextran Sulfate Sodium-Induced Colitis in the Early Phase

(2013) Hitoshi IWAYA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration

(2013) Y Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: Potential implications in cardiovascular disease

(2012) Jixin Zhong et al.   ATHEROSCLEROSIS

Stem cell compartmentalization in diabetes and high cardiovascular risk reveals the role of DPP-4 in diabetic stem cell mobilopathy

(2012) Gian Paolo Fadini et al.   BASIC RESEARCH IN CARDIOLOGY

Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4 inhibition

(2012) Swenja Kröller-Schön et al.   CARDIOVASCULAR RESEARCH

A Potential Role for Dendritic Cell/Macrophage-Expressing DPP4 in Obesity-Induced Visceral Inflammation

(2012) Jixin Zhong et al.   DIABETES

Exendin-4 inhibits iNOS expression at the protein level in LPS-stimulated Raw264.7 macrophage by the activation of cAMP/PKA pathway

(2012) Seo-Yoon Chang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A Dipeptidyl Peptidase-4 Inhibitor, Des-Fluoro-Sitagliptin, Improves Endothelial Function and Reduces Atherosclerotic Lesion Formation in Apolipoprotein E–Deficient Mice

(2012) Junichi Matsubara et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

α1AMP-Activated Protein Kinase Preserves Endothelial Function During Chronic Angiotensin II Treatment by Limiting Nox2 Upregulation

(2011) Swenja Schuhmacher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients

(2011) Paul A. J. Krijnen et al.   BASIC RESEARCH IN CARDIOLOGY

Long-Term Dipeptidyl-Peptidase 4 Inhibition Reduces Atherosclerosis and Inflammation via Effects on Monocyte Recruitment and Chemotaxis

(2011) Zubair Shah et al.   CIRCULATION

Lysozyme M–Positive Monocytes Mediate Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction

(2011) Philip Wenzel et al.   CIRCULATION

From Theory to Clinical Practice in the Use of GLP-1 Receptor Agonists and DPP-4 Inhibitors Therapy

(2011) Ilaria Dicembrini et al.   Experimental Diabetes Research

Vascular Dysfunction in Streptozotocin-Induced Experimental Diabetes Strictly Depends on Insulin Deficiency

(2011) Matthias Oelze et al.   JOURNAL OF VASCULAR RESEARCH

Glucagon-like peptide-1(1-37) inhibits chemokine-induced migration of human CD4-positive lymphocytes

(2010) Nikolaus Marx et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Psoriasis and cardiovascular disease

(2010) Gino A. Vena et al.   Dermatologic Therapy

Dipeptidyl-Peptidase 4 and Attractin Expression is Increased in Circulating Blood Monocytes of Obese Human Subjects

(2010) M. Laudes et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

GLP-1 signaling preserves cardiac function in endotoxemic Fischer 344 and DPP4-deficient rats

(2010) Hui-Chun Ku et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Airway-specific recruitment of T cells is reduced in a CD26-deficient F344 rat substrain

(2009) J. Schade et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Validation of Volume-Pressure Recording Tail-Cuff Blood Pressure Measurements

(2008) M. Feng et al.   AMERICAN JOURNAL OF HYPERTENSION

Nitric Oxide, Tetrahydrobiopterin, Oxidative Stress, and Endothelial Dysfunction in Hypertension

(2008) Eberhard Schulz et al.   ANTIOXIDANTS & REDOX SIGNALING

Suppression of the JNK Pathway by Induction of a Metabolic Stress Response Prevents Vascular Injury and Dysfunction

(2008) Eberhard Schulz et al.   CIRCULATION

AT1-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats

(2008) Philip Wenzel et al.   FREE RADICAL BIOLOGY AND MEDICINE

(R)-8-(3-Amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a Novel Xanthine-Based Dipeptidyl Peptidase 4 Inhibitor, Has a Superior Potency and Longer Duration of Action Compared with Other Dipeptidyl Peptidase-4 Inhibitors

(2008) L. Thomas et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2−/− mice

(2007) P Wenzel et al.   BRITISH JOURNAL OF PHARMACOLOGY