Journal
JOURNAL OF CLINICAL MONITORING AND COMPUTING
Volume 29, Issue 2, Pages 231-239Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s10877-014-9590-6
Keywords
Closed-loop anaesthesia; Model uncertainty; Fault-tolerant; MIMO; Depth of anaesthesia
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Funding
- ERGS - Ministry Of Higher Education Malaysia [ERGS/1-2012/5527093]
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Anaesthesia is a multivariable problem where a combination of drugs are used to induce desired hypnotic, analgesia and immobility states. The automation of anaesthesia may improve the safety and cost-effectiveness of anaesthesia. However, the realization of a safe and reliable multivariable closed-loop control of anaesthesia is yet to be achieved due to a manifold of challenges. In this paper, several significant challenges in automation of anaesthesia are discussed, namely model uncertainty, controlled variables, closed-loop application and dependability. The increasingly reliable measurement device, robust and adaptive controller, and better fault tolerance strategy are paving the way for automation of anaesthesia.
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