Hydrogen sulfide and PKG in ischemia–reperfusion injury: sources, signaling, accelerators and brakes

Hydrogen sulfide mediates the cardioprotective effects of gene therapy with PKG-Iα

(2015) Anindita Das et al.   BASIC RESEARCH IN CARDIOLOGY

Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway

(2015) Sofia-Iris Bibli et al.   CARDIOVASCULAR RESEARCH

Molecular Basis of Cardioprotection: Signal Transduction in Ischemic Pre-, Post-, and Remote Conditioning

(2015) G. Heusch   CIRCULATION RESEARCH

Diallyl trisulfide protects against high glucose-induced cardiac apoptosis by stimulating the production of cystathionine gamma-lyase-derived hydrogen sulfide

(2015) Cheng-Yen Tsai et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

(2015) John L. Wallace et al.   NATURE REVIEWS DRUG DISCOVERY

Selectivity of hydrogen sulfide toward cyclic nucleotide phosphodiesterases

(2015) Panagiotis Panopoulos et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen sulfide regulates the redox status of soluble guanylyl cyclase

(2015) Zongmin Zhou et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Protein kinase G–regulated production of H2S governs oxygen sensing

(2015) Guoxiang Yuan et al.   Science Signaling

Protein kinase G–regulated production of H2S governs oxygen sensing

(2015) Guoxiang Yuan et al.   Science Signaling

Soluble guanylyl cyclase activation improves progressive cardiac remodeling and failure after myocardial infarction. Cardioprotection over ACE inhibition

(2014) Daniela Fraccarollo et al.   BASIC RESEARCH IN CARDIOLOGY

Natriuretic peptides modulate ATP-sensitive K+ channels in rat ventricular cardiomyocytes

(2014) Dwaine S. Burley et al.   BASIC RESEARCH IN CARDIOLOGY

The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning

(2014) Ioanna Andreadou et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pharmacological tools for hydrogen sulphide research: a brief, introductory guide for beginners

(2014) Andreas Papapetropoulos et al.   BRITISH JOURNAL OF PHARMACOLOGY

Delayed phospholamban phosphorylation in post-conditioned heart favours Ca2+ normalization and contributes to protection

(2014) Javier Inserte et al.   CARDIOVASCULAR RESEARCH

Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition

(2014) Mariarosaria Bucci et al.   CARDIOVASCULAR RESEARCH

Emergence of Hydrogen Sulfide as an Endogenous Gaseous Signaling Molecule in Cardiovascular Disease

(2014) David J. Polhemus et al.   CIRCULATION RESEARCH

Protein Kinase G Iα Oxidation Paradoxically Underlies Blood Pressure Lowering by the Reductant Hydrogen Sulfide

(2014) Daniel Stubbert et al.   HYPERTENSION

Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent

(2014) A. L. King et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The coordination of S-sulfhydration, S-nitrosylation, and phosphorylation of endothelial nitric oxide synthase by hydrogen sulfide

(2014) Z. Altaany et al.   Science Signaling

Polysulfides Link H2S to Protein Thiol Oxidation

(2013) Romy Greiner et al.   ANTIOXIDANTS & REDOX SIGNALING

Enzymology of H2S Biogenesis, Decay and Signaling

(2013) Omer Kabil et al.   ANTIOXIDANTS & REDOX SIGNALING

Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G

(2013) Carmen Methner et al.   BASIC RESEARCH IN CARDIOLOGY

Hydrogen sulfide-mediated stimulation of mitochondrial electron transport involves inhibition of the mitochondrial phosphodiesterase 2A, elevation of cAMP and activation of protein kinase A

(2013) Katalin Módis et al.   BIOCHEMICAL PHARMACOLOGY

H 2 S Protects Against Pressure Overload–Induced Heart Failure via Upregulation of Endothelial Nitric Oxide Synthase

(2013) Kazuhisa Kondo et al.   CIRCULATION

Hydrogen Sulfide Attenuates Cardiac Dysfunction After Heart Failure Via Induction of Angiogenesis

(2013) David J. Polhemus et al.   Circulation-Heart Failure

Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I

(2013) Edward T Chouchani et al.   NATURE MEDICINE

The polysulfide diallyl trisulfide protects the ischemic myocardium by preservation of endogenous hydrogen sulfide and increasing nitric oxide bioavailability

(2012) Benjamin L. Predmore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide

(2012) Fadi N. Salloum et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Modulation of Cardiac Contractility by the Phopholamban/SERCA2a Regulatome

(2012) Evangelia G. Kranias et al.   CIRCULATION RESEARCH

Hydrogen Sulfide-Linked Sulfhydration of NF-κB Mediates Its Antiapoptotic Actions

(2012) Nilkantha Sen et al.   MOLECULAR CELL

Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed

(2012) Rui Wang   PHYSIOLOGICAL REVIEWS

cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation

(2012) Mariarosaria Bucci et al.   PLoS One

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

(2012) C. Coletta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary and comparative aspects of nitric oxide, carbon monoxide and hydrogen sulfide

(2012) Kenneth R. Olson et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Inhaled Nitric Oxide Improves Outcomes After Successful Cardiopulmonary Resuscitation in Mice

(2011) Shizuka Minamishima et al.   CIRCULATION

cGMP/PKG pathway mediates myocardial postconditioning protection in rat hearts by delaying normalization of intracellular acidosis during reperfusion

(2011) Javier Inserte et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardioprotective PKG-independent NO signaling at reperfusion

(2010) Michael V. Cohen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hydrogen Sulfide Is an Endogenous Inhibitor of Phosphodiesterase Activity

(2010) Mariarosaria Bucci et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genetic and Pharmacologic Hydrogen Sulfide Therapy Attenuates Ischemia-Induced Heart Failure in Mice

(2010) John W. Calvert et al.   CIRCULATION

Cardioprotective effects of hydrogen sulfide

(2010) Gábor Szabó et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen sulfide-mediated myocardial pre- and post-conditioning

(2010) Benjamin L Predmore et al.   Expert Review of Clinical Pharmacology

Phosphodiesterase-5 Inhibitor, Tadalafil, Protects Against Myocardial Ischemia/Reperfusion Through Protein-Kinase G-Dependent Generation of Hydrogen Sulfide

(2009) F. N. Salloum et al.   CIRCULATION

Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling

(2009) John W. Calvert et al.   CIRCULATION RESEARCH

Hydrogen sulfide is an endogenous stimulator of angiogenesis

(2009) A. Papapetropoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ANTI-APOPTOTIC AND ANTI-INFLAMMATORY EFFECTS OF HYDROGEN SULFIDE IN A RAT MODEL OF REGIONAL MYOCARDIAL I/R

(2009) Ahila Sivarajah et al.   SHOCK