Optogenetic control of insulin secretion in intact pancreatic islets with β-cell-specific expression of Channelrhodopsin-2

Insulin Hypersecretion in Islets From Diet-Induced Hyperinsulinemic Obese Female Mice Is Associated With Several Functional Adaptations in Individual β-Cells

(2013) Alejandro Gonzalez et al.   ENDOCRINOLOGY

Eukaryotic Translation Initiation Factor 3 Subunit E Controls Intracellular Calcium Homeostasis by Regulation of Cav1.2 Surface Expression

(2013) Pawel Buda et al.   PLoS One

Reduced Insulin Exocytosis in Human Pancreatic  -Cells With Gene Variants Linked to Type 2 Diabetes

(2012) A. H. Rosengren et al.   DIABETES

The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes

(2012) T. M. Reinbothe et al.   DIABETOLOGIA

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

(2012) Linda Madisen et al.   NATURE NEUROSCIENCE

Regulation of calcium in pancreatic α- and β-cells in health and disease

(2011) Patrik Rorsman et al.   CELL CALCIUM

Beta-Cell Specific Deletion of Dicer1 Leads to Defective Insulin Secretion and Diabetes Mellitus

(2011) Martins Kalis et al.   PLoS One

 -Cell Failure in Diet-Induced Obese Mice Stratified According to Body Weight Gain: Secretory Dysfunction and Altered Islet Lipid Metabolism Without Steatosis or Reduced  -Cell Mass

(2010) M.-L. Peyot et al.   DIABETES

A user's guide to channelrhodopsin variants: features, limitations and future developments

(2010) John Y. Lin   EXPERIMENTAL PHYSIOLOGY

Optogenetics

(2010) Karl Deisseroth   NATURE METHODS

Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures

(2010) Feng Zhang et al.   Nature Protocols

Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes

(2009) A. H. Rosengren et al.   SCIENCE

Somatostatin Secreted by Islet  -Cells Fulfills Multiple Roles as a Paracrine Regulator of Islet Function

(2008) A. C. Hauge-Evans et al.   DIABETES

Dual Effect of Cell-Cell Contact Disruption on Cytosolic Calcium and Insulin Secretion

(2008) Fabienne Jaques et al.   ENDOCRINOLOGY