The MMP-1/PAR-1 Axis Enhances Proliferation and Neuronal Differentiation of Adult Hippocampal Neural Progenitor Cells

Activated protein C: biased for translation

(2015) J. H. Griffin et al.   BLOOD

The current state of the neurogenic theory of depression and anxiety

(2015) Bradley R Miller et al.   CURRENT OPINION IN NEUROBIOLOGY

Tricyclic Antidepressant Amitriptyline-induced Glial Cell Line-derived Neurotrophic Factor Production Involves Pertussis Toxin-sensitive Gαi/oActivation in Astroglial Cells

(2015) Kazue Hisaoka-Nakashima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix metalloproteinase-2 and -9 in the cerebellum of teleost fish: Functional implications for adult neurogenesis

(2015) Ruxandra F. Sîrbulescu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat's hippocampus

(2014) Wenyu Cao et al.   BEHAVIOURAL BRAIN RESEARCH

Not all water mazes are created equal: cyclin D2 knockout mice with constitutively suppressed adult hippocampal neurogenesis do show specific spatial learning deficits

(2014) A. Garthe et al.   GENES BRAIN AND BEHAVIOR

Characterization of the role of adult neurogenesis in touch-screen discrimination learning

(2014) Alicia A. Swan et al.   HIPPOCAMPUS

Endosomal generation of cAMP in GPCR signaling

(2014) Jean-Pierre Vilardaga et al.   Nature Chemical Biology

Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases

(2014) Alexander C W Smith et al.   NATURE NEUROSCIENCE

Consequences of cancer treatments on adult hippocampal neurogenesis: implications for cognitive function and depressive symptoms

(2014) G. Pereira Dias et al.   NEURO-ONCOLOGY

Activity-controlled proteolytic cleavage at the synapse

(2014) Peter Sonderegger et al.   TRENDS IN NEUROSCIENCES

Type 1 metalloproteinase is selectively expressed in adult rat brain and can be rapidly up-regulated by kainate

(2013) Victor N. Ierusalimsky et al.   ACTA HISTOCHEMICA

Activated protein C analog promotes neurogenesis and improves neurological outcome after focal ischemic stroke in mice via protease activated receptor 1

(2013) Yaoming Wang et al.   BRAIN RESEARCH

An Activated Protein C Analog Stimulates Neuronal Production by Human Neural Progenitor Cells via a PAR1-PAR3-S1PR1-Akt Pathway

(2013) H. Guo et al.   JOURNAL OF NEUROSCIENCE

High-Mobility Group Box-1 Protein and  -Amyloid Oligomers Promote Neuronal Differentiation of Adult Hippocampal Neural Progenitors via Receptor for Advanced Glycation End Products/Nuclear Factor- B Axis: Relevance for Alzheimer's Disease

(2013) V. Meneghini et al.   JOURNAL OF NEUROSCIENCE

Resistance Exercise Increases Endothelial Progenitor Cells and Angiogenic Factors

(2013) MARK D. ROSS et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Upregulation of mGlu2 Receptors via NF-κB p65 Acetylation Is Involved in the Proneurogenic and Antidepressant Effects of Acetyl-L-Carnitine

(2013) Bruna Cuccurazzu et al.   NEUROPSYCHOPHARMACOLOGY

Matrix Metalloproteinase-1-mediated Up-regulation of Vascular Endothelial Growth Factor-2 in Endothelial Cells

(2012) Rafi Mazor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic circuit remodelling by matrix metalloproteinases in health and disease

(2012) George W. Huntley   NATURE REVIEWS NEUROSCIENCE

Thrombin regulation of synaptic transmission: Implications for seizure onset

(2012) Nicola Maggio et al.   NEUROBIOLOGY OF DISEASE

Vascular endothelial growth factor regulates adult hippocampal cell proliferation through MEK/ERK- and PI3K/Akt-dependent signaling

(2012) Neil M. Fournier et al.   NEUROPHARMACOLOGY

Activation of cerebral recovery by matrix metalloproteinase-9 after intracerebral hemorrhage

(2012) C. Lei et al.   NEUROSCIENCE

A matrix metalloprotease-PAR1 system regulates vascular integrity, systemic inflammation and death in sepsis

(2011) Sarah L. Tressel et al.   EMBO Molecular Medicine

Serine and metalloprotease signaling through PAR1 in arterial thrombosis and vascular injury

(2011) Georgios Koukos et al.   IUBMB LIFE

Influence of matrix metalloproteinase MMP-9 on dendritic spine morphology

(2011) P. Michaluk et al.   JOURNAL OF CELL SCIENCE

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

(2011) Guo-li Ming et al.   NEURON

Necessity of Hippocampal Neurogenesis for the Therapeutic Action of Antidepressants in Adult Nonhuman Primates

(2011) Tarique D. Perera et al.   PLoS One

The Potential Role of Metalloproteinases in Neurogenesis in the Gerbil Hippocampus Following Global Forebrain Ischemia

(2011) Luiza Wójcik-Stanaszek et al.   PLoS One

Activation of protease activated receptor 1 increases the excitability of the dentate granule neurons of hippocampus

(2011) Kyung-Seok Han et al.   Molecular Brain

Evidence of reactive astrocytes but not peripheral immune system activation in a mouse model of Fragile X syndrome

(2010) Christopher J. Yuskaitis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Signal transduction by protease-activated receptors

(2010) Unice JK Soh et al.   BRITISH JOURNAL OF PHARMACOLOGY

RBPJ -Dependent Signaling Is Essential for Long-Term Maintenance of Neural Stem Cells in the Adult Hippocampus

(2010) O. Ehm et al.   JOURNAL OF NEUROSCIENCE

Fragile X Mental Retardation Protein Regulates Proliferation and Differentiation of Adult Neural Stem/Progenitor Cells

(2010) Yuping Luo et al.   PLoS Genetics

Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh

(2009) Rebecca Favaro et al.   NATURE NEUROSCIENCE

Matrix Metalloproteinase-1 and Thrombin Differentially Activate Gene Expression in Endothelial Cells via PAR-1 and Promote Angiogenesis

(2008) Jessica S. Blackburn et al.   AMERICAN JOURNAL OF PATHOLOGY

Impaired Adult Neurogenesis Associated with Short-Term Memory Defects in NF- B p50-Deficient Mice

(2008) S. Denis-Donini et al.   JOURNAL OF NEUROSCIENCE

Activated Protein C Promotes Neovascularization and Neurogenesis in Postischemic Brain via Protease-Activated Receptor 1

(2008) M. Thiyagarajan et al.   JOURNAL OF NEUROSCIENCE

Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer

(2008) A. Agarwal et al.   MOLECULAR CANCER THERAPEUTICS

Endogenous Matrix Metalloproteinase (MMP)-3 and MMP-9 Promote the Differentiation and Migration of Adult Neural Progenitor Cells in Response to Chemokines

(2008) Basam Z. Barkho et al.   STEM CELLS

Effects of Thrombin on Neurogenesis After Intracerebral Hemorrhage

(2008) Shuxu Yang et al.   STROKE