Article
Infectious Diseases
Alexandre Baudet, Monique Guillaso, Leonie Grimmer, Marie Regad, Arnaud Florentin
Summary: The study investigated the microbiological contamination in dental and general practitioner offices, finding bacterial and fungal contamination but rare pathogenic micro-organisms. Some antibiotic-resistant bacteria were identified in general practitioner offices, but not in dental offices.
Article
Medicine, General & Internal
He-Ning Wu, Er-Yan Yuan, Wen-Bin Li, Min Peng, Qing-Yu Zhang, Ke-liang Xie
Summary: This study retrospectively analyzed the microbiological and clinical data of bloodstream infection (BSI) patients in an ICU in Tianjin, China. The results showed that Gram-negative bacteria had the highest drug resistance rate and resulted in more severe brain damage, renal function damage, and thrombocytopenia. The test index of procalcitonin (PCT) could be used to distinguish Gram-negative bacteremia from Gram-positive and differentiate bacteremia from fungemia, but further research is needed.
FRONTIERS IN MEDICINE
(2022)
Article
Environmental Sciences
Bartlomiej Blaszczyk, Magdalena Pajaczkowska, Joanna Nowicka, Maria Szymonowicz, Wojciech Zakrzewski, Adam Lubojanski, Marlena Hercun-Jaskolka, Aleksandra Synowiec, Sebastian Fedorowicz, Wojciech Dobrzynski, Zbigniew Rybak, Maciej Dobrzynski
Summary: This study investigated the microbial count in water samples from different parts of dental units in direct contact with patients. The results showed the presence of bacteria and fungi in the water of dental units, including potentially harmful bacteria. The study highlights the need for effective decontamination of water used in dental units and continuous monitoring of contaminant levels.
Article
Medicine, General & Internal
Wei Chai, Yuqing Wang, Huancheng Zheng, Song Yue, Yan Liu, Yili Wu, Xuezhi Li
Summary: The study analyzed the pathogen spectrum and antibiotic susceptibility of diabetic foot ulcers, finding that dominant pathogens were sensitive to at least one antibiotic, but the antibacterial efficacy of common antibiotics decreased over time. Identification and testing of antibiotic susceptibility of dominant pathogens are essential for effective treatment of diabetic foot ulcers.
FRONTIERS IN MEDICINE
(2021)
Article
Engineering, Environmental
Michel A. Hoogenkamp, Bernd W. Brandt, Alexa M. G. A. Laheij, Johannes J. de Soet, Wim Crielaard
Summary: This study found that dental unit water systems in the Netherlands are prone to biofilm formation, with microbial load and composition influenced by various factors. Significant effects on microbial load and microbiome were only seen when adhering to disinfection protocols. Analysis of relaxed biofilm samples provides better insight into the presence of opportunistic pathogens compared to traditional methods like heterotrophic plate counts.
Article
Infectious Diseases
Catarina Geraldes, Claudia Verdial, Eva Cunha, Virgilio Almeida, Luis Tavares, Manuela Oliveira, Solange Gil
Summary: Hospital-acquired infections are a growing problem worldwide, and the best way to cope with them is through prevention strategies and efficient disinfection protocols. The study showed that the Minimal Bactericidal Concentration (MBC) of Virkon(S) was at least eight times lower than the regular concentration when no organic matter was present, but rose to 23 times in the presence of organic matter. Additionally, a potential stress-induced response may explain the changes in antimicrobial susceptibility observed after exposure to sub-lethal concentrations of Virkon(S).
Article
Medicine, General & Internal
Jin-Jhe Wang, Chien-Hsiung Lai, Chau-Yin Chen, Chia-Yen Liu, Meng-Hung Lin, Yao-Hsu Yang, Pei-Lun Wu
Summary: This study investigated the demographics, risk factors, microbiological characteristics, and antibiotic susceptibility patterns of infectious keratitis (IK) in Taiwan over the past 15 years. The findings showed a decline in contact lens-related IK and an increase in IK related to systemic diseases. Gram-positive bacteria were more commonly isolated than gram-negative bacteria. The prevalence of Pseudomonas aeruginosa showed a decreasing trend, while coagulase-negative Staphylococcus and Propionibacterium species were increasingly detected. Antibiotic susceptibility of both gram-positive and gram-negative bacteria remained stable throughout the study period.
Article
Medicine, General & Internal
Min Gu Park, Sung Yong Cho, Se Yun Kwon, Hoon Choi, Jeong Woo Lee
Summary: The study found that male patients in the HA group were older, had longer hospital stays, more underlying diseases, and higher rates of bacteremia and intensive care unit admissions. Escherichia coli was the most commonly cultured microorganism. Sensitivity to fluoroquinolone and the proportion of extended-spectrum beta-lactamase-producing bacteria were higher in the CA group than in the HA group.
Article
Dentistry, Oral Surgery & Medicine
Charlotte C. Currie, Simon J. Stone, Paul Brocklehurst, Wendy Thompson, Justin Durham, Mark S. Pearce
Summary: This study explored trends and predictors for antibiotic prescriptions and referrals at General Medical Practitioners (GMPs) for dental care. The results showed that antibiotic prescriptions were associated with living in deprived or rural areas, while referrals were associated with living in urban or less deprived areas. The number of antibiotic prescriptions decreased over time, while the number of referrals increased. These changes were linked to dental attendance rates at GMPs and indicate the need to change current practice and policy.
JOURNAL OF DENTISTRY
(2023)
Article
Biotechnology & Applied Microbiology
Zhangming Pei, Yufei Liu, Fang Zhao, Hongchao Wang, Jianxin Zhao, Wei Chen, Wenwei Lu
Summary: This study collected 422 gut-derived bifidobacterial strains from the Chinese population and determined their phenotypic resistance profiles against ten commonly used antibiotics. Different Bifidobacterium species exhibited varying tolerances to the same antibiotic, leading to the establishment of species-specific cut-off values for the determination of phenotypic resistance. In addition, a comprehensive scanning of antibiotic resistance genes revealed the association between the tetracycline resistance gene tet(W), erythromycin/clindamycin resistance gene ErmX, and host phenotypes. These findings provide guidance and reference values for the safe application of bifidobacteria in the food industry and the development of probiotic resistance evaluation standards.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Thais Mazzetti, Kaue Collares, Bruna Rodolfo, Paullo Antonio da Rosa Rodolpho, Francoise Helene van de Sande, Maximiliano Sergio Cenci
Summary: This study compared the survival and success rates of direct resin composite and ceramic veneers placed in a private dental practice. The results showed that ceramic veneers had superior longevity and success rates compared to direct resin composite veneers.
Article
Dentistry, Oral Surgery & Medicine
Raphael Florentino Souza Barbalho De Medeiros, Regia Carla Medeiros da Silva, Liliane Cristina Nogueira Marinho, Davi Neto de Araujo Silva, Isabelle Lisiany de Lima Tavares, Camila Alfrida Cabral Nascimento Rocha Antunes de Lima, Maria Celeste Nunes de Melo, Roberta Correia Sales, Domingos Savio Barbalho de Medeiros, Beatriz Bezerra, Ericka Janine Dantas da Silveira, Ana Rafaela Luz de Aquino Martins
Summary: This study identifies the presence of Pseudomonas aeruginosa and Staphylococcus aureus in oral biofilms of intubated and non-intubated patients in an ICU. Both bacteria showed resistance to multiple antimicrobial agents.
Review
Ophthalmology
Joveeta Joseph, Roshini Karoliya, Esther Sheba, Savitri Sharma, Bhupesh Bagga, Prashant Garg
Summary: The purpose of this study was to assess the trends in microorganisms causing infectious keratitis and their antibiotic susceptibility patterns at a tertiary eye care center in India. Retrospective review of microbiological records from 1991 to 2020 revealed a decrease in bacteria and an increase in fungal isolates. Gram-positive bacteria, particularly Streptococcus pneumoniae, showed a rising trend, while Staphylococcus epidermidis decreased over the 30-year period. Pseudomonas aeruginosa was the most prevalent gram-negative pathogen, and Fusarium spp. and Aspergillus spp. were the most common fungal isolates. Resistance to various antibiotics, including fluoroquinolones, showed an increasing trend. The changing spectrum of keratitis and the rising antibiotic resistance emphasize the importance of regular surveillance.
Article
Infectious Diseases
Cecilia Herbozo, Irene Julca, Fiorella Flores, Roger Hernandez, Jaime Zegarra
Summary: This study aimed to determine the incidence of late onset sepsis and the most frequent causative microorganisms in the neonatal unit at Hospital Cayetano Heredia in Lima, Peru. The results showed that late onset sepsis was more prevalent in low birth weight infants, with gram-negative bacteria being the main causative microorganism in very low birth weight infants.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Microbiology
Celine Plainvert, Erika Matuschek, Nicolas Dmytruk, Marine Gaillard, Amandine Frigo, Yassine Ballaa, Eddy Biesaga, Gunnar Kahlmeter, Claire Poyart, Asmaa Tazi
Summary: NBHS are opportunistic pathogens frequently causing severe and difficult-to-treat infections such as endocarditis. This study highlights their importance and resistance to antibiotics, especially beta-lactam agents. A multicenter study conducted in France described the clinical and microbiological epidemiology of invasive NBHS infections, emphasizing the need for accurate species identification and antimicrobial susceptibility testing for effective treatment.
MICROBIOLOGY SPECTRUM
(2023)
