Article
Biochemistry & Molecular Biology
Claude Bernard Jean-Guillaume, Justin P. Kumar
Summary: The adult visual system of the fruit fly, Drosophila melanogaster, consists of different eye types with specialized roles, but little is known about the specification and patterning of two of these eye types.
Article
Multidisciplinary Sciences
Maria Bortot, Giorgio Vallortigara
Summary: The study found that honeybees are able to generalize from the size dimension to the number dimension, suggesting the existence of a universal mechanism for encoding abstract magnitudes in invertebrates similar to that of vertebrates.
Article
Biology
Lei Guo, Xin-yu Fan, Xiaomu Qiao, Craig Montell, Jia Huang
Summary: The study revealed that amitraz activates octopamine receptors in Varroa mites, with bees being relatively insensitive to it. Bees resist amitraz through their insensitive receptors, which has implications for resistance management and the development of safer insecticides targeting pests while being less toxic to non-target pollinators.
Article
Biology
Peilin Zhao, Tao Jiang, Huading Wang, Xueyan Jia, Anan Li, Hui Gong, Xiangning Li
Summary: By studying the detailed morphology of pontine-tegmental cholinergic neurons (PTCNs), we found that these neurons have abundant axons and collaterals, and can project to multiple brain regions in both the ascending and descending circuits, including the thalamus and cortex. Based on labeling in different circuits, PTCNs can be classified into four subtypes. These findings provide important organizational characteristics of cholinergic neurons in the upper brainstem to understand their connexional logic.
Article
Optics
Xin Zhang, Ke Kang, Yanfang Jiang, Jiaxue He, Yanfeng Qiao
Summary: This study proposes a novel double-layer focal plane microscope that doubles the throughput of DNA sequencing. By dividing the fluorescence channels and adjusting the camera, the information capacity of the microscope is effectively increased. Experimental results show that the throughput is doubled while the signal-to-noise ratio of the images is slightly reduced.
Article
Biochemistry & Molecular Biology
Yuri Ogawa, Sarah Nicholas, Malin Thyselius, Richard Leibbrandt, Thomas Nowotny, James C. Knight, Karin Nordstrom
Summary: Many animals, including predators and male hoverflies, use motion vision information to detect and pursue moving targets. This study investigated the response of target-selective descending neurons (TSDNs) in male hoverflies during pursuits of artificial targets. The results showed that individual TSDNs responded consistently at specific time points, but with variations between neurons. The overall response rate was low, suggesting that different neurons may control different parts of the behavioral output.
Article
Biochemistry & Molecular Biology
Michal Bulc, Jaroslaw Calka, Katarzyna Palus
Summary: Environmental and food contamination pose a major threat to animal and human health. Glyphosate, a common contaminant in soil, has effects on the population and immune response of porcine descending colon neurons, particularly at high doses.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Engineering, Civil
Jiawei Shan, Gang Zhang, Chufeng Tang, Hujie Pan, Qiankun Yu, Guanhao Wu, Xiaolin Hu
Summary: In this study, a new distillation method called Focal Distillation is proposed to improve the performance of low-resolution LiDAR detectors by leveraging high-resolution detectors. Extensive experiments show significant improvements on different datasets and models, demonstrating the generalization ability of the proposed method.
IEEE TRANSACTIONS ON INTELLIGENT TRANSPORTATION SYSTEMS
(2023)
Article
Materials Science, Multidisciplinary
Peng Lin, Yu-Sheng Lin, Jie Lin, Bo-Ru Yang
Summary: The stretchable metalens proposed in this study can achieve highly tunable focal length and achromatic characteristics by stretching along x and y-axis directions. The focal length remains stable and shows a linear relationship with the change in the period of the metalens. By stretching the period of the metalens, the focal lengths can be tuned in a linear range for incident wavelengths ranging from 480 nm to 660 nm, with a tuning range of over 200% for these wavelengths.
RESULTS IN PHYSICS
(2021)
Review
Neurosciences
Eileen Nguyen, Jose G. Grajales-Reyes, Robert W. Gereau Iv, Sarah E. Ross
Summary: Decades of research have revealed that stimulation of supraspinal structures like PAG and RVM can inhibit nocifensive responses through descending modulation. Advances in genetic, imaging, and tracing methods have provided detailed insights into the cells and circuits involved in descending modulation. Recent studies have shown the importance of PAG and RVM in coordinating complex behavioral responses to sensory input. This review highlights the role of new technical advances in expanding our understanding of descending modulation.
TRENDS IN NEUROSCIENCES
(2023)
Article
Neurosciences
Xinglong Gu, Yizhen Z. Z. Zhang, John J. O'Malley, Caitlynn C. De Preter, Mario Penzo, Mark A. Hoon
Summary: In this study, the researchers identified catecholaminergic neurons in the caudal ventrolateral medulla that are activated by noxious stimuli in mice. These neurons produce bilateral feed-forward inhibition to attenuate nociceptive responses through a pathway involving the locus coeruleus and norepinephrine in the spinal cord. This pathway plays a role in attenuating injury-induced heat allodynia and counter-stimulus induced analgesia to noxious heat.
NATURE NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Vasile V. Moca, Harald Barzan, Adriana Nagy-Dabacan, Raul C. Muresan
Summary: The use of superlets allows for high resolution in both time and frequency, resolving data containing fast transient oscillation events.
NATURE COMMUNICATIONS
(2021)
Article
Multidisciplinary Sciences
Natthakan Thongon, Feiyang Ma, Andrea Santoni, Matteo Marchesini, Elena Fiorini, Ashley Rose, Vera Adema, Irene Ganan-Gomez, Emma M. Groarke, Fernanda Gutierrez-Rodrigues, Shuaitong Chen, Pamela Lockyer, Sarah Schneider, Carlos Bueso-Ramos, Guillermo Montalban-Bravo, Caleb A. Class, Kelly A. Soltysiak, Matteo Pellegrini, Ergun Sahin, Alison A. Bertuch, Courtney D. DiNardo, Guillermo Garcia-Manero, Neal S. Young, Karen Dwyer, Simona Colla
Summary: The study reveals that telomere attrition leads hematopoietic stem cells towards differentiation into megakaryocytic lineage through upregulated innate immune signaling response, ultimately compromising their self-renewal capabilities and leading to depletion. Targeting the IFI16 signaling axis could potentially prevent functional decline of hematopoietic stem cells under conditions affecting telomere maintenance.
NATURE COMMUNICATIONS
(2021)
Article
Marine & Freshwater Biology
Abigail M. Smith, Bryce A. Peebles, Hamish G. Spencer
Summary: The dorsal shell surface of the New Zealand-endemic chitonid Onithochiton neglectus has ocelli associated with sensory organs, which can potentially resolve images. Experimental results showed that the lenses of O. neglectus have good imaging ability in air, and the visual acuity of chitons varies in different habitats.
MOLLUSCAN RESEARCH
(2023)
Article
Geochemistry & Geophysics
Bruno Giammarinaro, Christina Tsarsitalidou, Gregor Hillers, Julien de Rosny, Leonard Seydoux, Stefan Catheline, Michel Campillo, Philippe Roux
Summary: Numerical experiments are conducted to explore subsurface imaging at subwavelength distances for dense seismic arrays in a laterally homogeneous layered medium. A time-reversal approach is used to simulate fundamental mode Rayleigh surface wavefields, and it is found that synthesized spatial autocorrelation fields support focal spot imaging. The accuracy of phase velocity and dispersion estimates obtained from focal spot properties is assessed through systematic tests involving different wave components and incidence conditions. The results indicate that dense array seismic Rayleigh wave focal spot imaging can increase depth sensitivity and support subwavelength resolution of lateral medium variations.
GEOPHYSICAL JOURNAL INTERNATIONAL
(2023)
Article
Neurosciences
Parvin Zarei Eskikand, Tatiana Kameneva, Anthony N. Burkitt, David B. Grayden, Michael R. Ibbotson
FRONTIERS IN NEURAL CIRCUITS
(2020)
Article
Materials Science, Biomaterials
Md. . Kabir Uddin Sikder, Wei Tong, Hitesh Pingle, Peter Kingshott, Karina Needham, Mohit N. Shivdasani, James B. Fallon, Peter Seligman, Michael R. Ibbotson, Steven Prawer, David J. Garrett
Summary: Coating electrodes with biomolecules like extracellular matrix proteins can suppress adverse biological responses and maintain optimal electrochemical performance for neural stimulation. The method of covalently coupling biomolecules to diamond electrodes enhances cell attachment densities and neurite outgrowth, showing promise in reducing inflammatory responses in vivo.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Review
Neurosciences
Danli Peng, Wei Tong, David J. Collins, Michael R. Ibbotson, Steven Prawer, Melanie Stamp
Summary: The study of neurons is essential for basic neuroscience research and treatment of neurological disorders. Ultrasound has emerged as a promising method for stimulating neurons, with surface acoustic wave (SAW) devices showing potential to address limitations of traditional transducers. SAW devices produce less self-heating, smaller size, and less cavitation, making them suitable for wearable or implantable neuromodulation devices.
FRONTIERS IN NEUROSCIENCE
(2021)
Editorial Material
Neurosciences
Peter Bartho
JOURNAL OF PHYSIOLOGY-LONDON
(2021)
Article
Neurosciences
Shi H. Sun, Ali Almasi, Molis Yunzab, Syeda Zehra, Damien G. Hicks, Tatiana Kameneva, Michael R. Ibbotson, Hamish Meffin
Summary: Different spike waveforms, regular-spiking (RS), fast-spiking (FS), and positive-spiking (PS), were identified in extracellular recordings in the visual cortex. PS units, associated with non-oriented receptive fields, are hypothesized to be recordings from thalamic axons. Correlating spike shapes with receptive field characteristics may lead to increased information extraction in future experiments.
JOURNAL OF PHYSIOLOGY-LONDON
(2021)
Review
Neurosciences
Maryam Hejazi, Wei Tong, Michael R. Ibbotson, Steven Prawer, David J. Garrett
Summary: Carbon-based microfiber electrodes have emerged as important tools in neural interfacing devices, showing advantages such as reduced foreign body responses, improved signal-to-noise ratio, and enhanced resolution. These electrodes are expected to improve the longevity and reliability of such devices.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Ophthalmology
Marianne Piano, Cirous Dehghani, Neville Turner, Allison McKendrick, Michael Ibbotson
Summary: The aim of this study is to analyze the ocular health and sociodemographic characteristics of Australian College of Optometry service users, and explore the relationship between key sociodemographic characteristics and eye health. The results show that visual impairment is more prevalent among service users examined in domiciliary settings, and increasing co-morbidities are associated with poorer best-corrected distance visual acuity. Aboriginal and Torres Strait Islander service users have a lower overall prevalence of visual impairment, but proportionally fewer aged >= 50 years attend for eye care compared to non-indigenous individuals.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2022)
Article
Neurosciences
Ali Almasi, Shi Hai Sun, Molis Yunzab, Young Jun Jung, Hamish Meffin, Michael R. Ibbotson
Summary: In this study, we examined the changes in neuronal receptive field (RF) models in response to different types of stimuli and discovered that V1 neurons respond differently to white Gaussian noise (WGN) and natural scenes (NSs), with stronger and faster responses to NSs. The most significant finding is that NSs lead to RFs with additional uncovered filters, which is not solely due to the increase in spike rates. These results reveal the existence of nonlinear mechanisms in V1 neurons when processing NSs.
JOURNAL OF NEUROSCIENCE
(2022)
Editorial Material
Neurosciences
Wei Tong, Michael R. Ibboston, Diego Ghezzi
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Engineering, Biomedical
Molis Yunzab, Artemio Soto-Breceda, Matias Maturana, Stephanie Kirkby, Maximilian Slattery, Anton Newgreen, Hamish Meffin, Tatiana Kameneva, Anthony N. Burkitt, Michael Ibbotson, Wei Tong
Summary: This study proposes a stimulation strategy to preferentially stimulate individual RGCs based on their temporal electrical receptive fields (tERFs). By reconstructing the tERFs and comparing characteristics based on cell morphology and light response types, the researchers were able to preferentially stimulate individual RGCs with lower activation thresholds to their own tERFs using stimulation trains composed of tERFs obtained from different cells. This proposed stimulation strategy may improve the quality of artificial vision in the next generation of retinal prostheses.
JOURNAL OF NEURAL ENGINEERING
(2022)
Article
Multidisciplinary Sciences
Young Jun Jung, Ali Almasi, Shi H. Sun, Molis Yunzab, Shaun L. Cloherty, Sebastien H. Bauquier, Marilyn Renfree, Hamish Meffin, Michael R. Ibbotson
Summary: Primary visual cortices in many mammalian species exhibit modular and periodic orientation preference maps, but the cortical organization of Australian marsupials resembles that of eutherian carnivores and primates rather than eutherian rodents and rabbits. This suggests that the genetic code enabling complex pinwheel formation may be widespread and present in common therian ancestors of modern mammals.
Article
Mechanics
Danli Peng, Wei Tong, David J. Collins, Michael R. Ibbotson, Steven Prawer, Melanie E. M. Stamp
Summary: Excitation using surface acoustic waves (SAW) has been proven effective in improving microscale particle/chemical transport by generating microscale wavelengths. However, the effects and mechanisms of acoustic stimulation on transport processes along sub-wavelength microchannels have not been fully explored. In this study, we investigate diffusion along subwavelength microchannels and find enhanced transport under SAW excitation. The enhancement is influenced by applied power, microchannel dimensions, and viscosity, and the findings have implications for microfluidic and biomedical transport enhancement.
Article
Nanoscience & Nanotechnology
Melanie E. M. Stamp, Wei Tong, Kumaravelu Ganesan, Steven Prawer, Michael R. Ibbotson, David J. Garrett
ACS APPLIED BIO MATERIALS
(2020)
Article
Engineering, Biomedical
Rachael Theresa Richardson, Michael R. Ibbotson, Alexander C. Thompson, Andrew K. Wise, James B. Fallon
HEALTHCARE TECHNOLOGY LETTERS
(2020)
Review
Neurosciences
Michael Ibbotson, Young Jun Jung
FRONTIERS IN SYSTEMS NEUROSCIENCE
(2020)
