Article
Food Science & Technology
Han Hu, Huihui Lin, Lei Xiao, Minqi Guo, Xi Yan, Xueqian Su, Lianliang Liu, Shangyuan Sang
Summary: This study showed that the addition of wheat bran and oat bran negatively affected the texture and color of bread, while the addition of beta-glucan did not have a significant impact. The beta-glucan in oat bran may be the key component in reducing the glycemic index of whole oat bread.
Article
Food Science & Technology
Alina Climova, Monica Ibrahim, Alisa Salamahina, Artemii M. Savin, Marina S. Dukhinova, Nadezhda V. Barakova, Elena F. Krivoshapkina
Summary: The study extracted beta-glucan from oat bran using the hot-water extraction method, achieving the highest yield compared to enzymatic, acid, and alkaline methods. This beta-glucan was then used as a coating material for encapsulating beta-carotene, resulting in stable polysaccharide-carotenoid system with potential application in the food industry. The cytotoxic analysis showed cell viability over 70%, indicating its potential usage.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2021)
Article
Agriculture, Multidisciplinary
Jingjie Zhang, Mengjun Zheng, Linyue Zhou, Xinping Li, Yonghui Yu, Jing Wang, Baoguo Sun
Summary: This study found that oat beta-glucan can reverse tumor necrosis factor-alpha induced abnormal myoblast differentiation and reduce muscle atrophy. The similar effects were observed when NLRP3 or FoxO1 inhibitors were used. Exposure to beta-glucan or AS1842856 inhibited TNF-alpha induced activation of TLR4/NF-kappa B pathway and decreased the expression of NLRP3. These findings indicate that oat beta-glucan plays essential roles in promoting myoblast differentiation and alleviating muscle atrophy by inactivating FoxO1 and NLRP3 inflammasome signal pathway.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Food Science & Technology
Joaquin Garcia-Cordero, Jose Luis Sierra-Cinos, Miguel A. Seguido, Susana Gonzalez-Ramila, Raquel Mateos, Laura Bravo-Clemente, Beatriz Sarria
Summary: The study investigated the effects of regularly consuming supplements containing green coffee polyphenols, beta-glucans, or their combination on body composition in overweight/obese subjects without changing their dietary and physical activity habits. The results showed that there were no changes in body composition parameters with any of the supplements, indicating that regular intake of these supplements without lifestyle changes is not an effective weight loss strategy.
Review
Nutrition & Dietetics
Andreea Zurbau, Jarvis C. Noronha, Tauseef A. Khan, John L. Sievenpiper, Thomas M. S. Wolever
Summary: Oat beta-glucan has been shown to reduce postprandial glucose and insulin responses, with the magnitude of glucose reduction depending on dose, molecular weight, and comparator. Different comparator meals result in a significantly larger reduction in glucose and insulin responses compared to similar control meals.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Chemistry, Applied
Yingying Qin, Jing Xie, Bin Xue, Xiaohui Li, Jianhong Gan, Ting Zhu, Tao Sun
Summary: Different degradation methods (acid and oxidative) result in distinctive structures and functionalities of oat beta-glucan oligosaccharides, affecting properties such as viscosity, fat binding capacity, and glucose availability. Acid or oxidative degradation of oat beta-glucan enhances its antioxidant, antibacterial, and hypoglycemic effects.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Applied
Kai Huang, Shurong Zhang, Xiao Guan, Cheng Li, Sen Li, Yongyong Liu, Jialong Shi
Summary: This study produced a novel plant-based milk from quinoa with the addition of oat beta-glucan (OGB), which efficiently prevented phase separation and improved stability. The optimal OGB concentration was found to be 16%, as it led to higher apparent viscosity, narrower particle distribution, and improved storage stability.
Article
Chemistry, Applied
Salla Hakkola, Lotta Nylund, Natalia Rosa-Sibakov, Baoru Yang, Emilia Nordlund, Tapio Pahikkala, Marko Kalliomaki, Anna-Marja Aura, Kaisa M. Linderborg
Summary: The study found that consumption of low molecular weight beta-glucan led to higher excretion of ferulic acid in urine, and lower excretion of deoxycholic and chenodeoxycholic acids in feces. Consumption of high molecular weight beta-glucan resulted in higher duodenal pressure, while the molecular weight of beta-glucan did not affect perceptions of gut well-being, though perceptions differed between females and males.
Article
Chemistry, Applied
Stelios D. Sarantis, Necla Mine Eren, Barbara Kowalcyk, Rafael Jimenez-Flores, Valente B. Alvarez
Summary: This study investigated the interaction mechanism between oat beta-glucan and casein, showing that thermal treatments increased biopolymer compatibility and suspension stability, leading to smaller particle sizes and improved stability. Higher ionic strength decreased compatibility and stability while increasing particle sizes, with entropic biopolymer interactions observed through isothermal titration calorimetry.
FOOD HYDROCOLLOIDS
(2021)
Article
Polymer Science
Peter Hozlar, Veronika Gregusova, Peter Nemecek, Svetlana Slikova, Michaela Havrlentova
Summary: Oats are an important natural source of beta-D-glucan, which has various health-promoting effects in plants and human bodies. This study found variations in the accumulation of beta-D-glucan in different parts of oats during growth, influenced by variety and sampling date.
Article
Food Science & Technology
Junying Bai, Yan Li, Wenhui Zhang, Mingcong Fan, Haifeng Qian, Hui Zhang, Xiguang Qi, Li Wang
Summary: This study investigated the effect of gut microbial source on oat beta-glucan metabolism by using mice and human fecal microbiota in an in vitro fermentation experiment. The main end products from gut microbial fermentation of beta-glucan were acetate, propionate, and butyrate, with differences in the main product between the mice and human groups. The data suggested that beta-glucan could be completely hydrolyzed by human fecal microbiota but not thoroughly degraded by mice fecal microbiota.
Article
Food Science & Technology
Victoria C. Blake, Charlene P. Wight, Eric Yao, Taner Z. Sen
Summary: GrainGenes is a database and web resource for wheat, barley, oat, rye, and their relatives, aiming to provide resources for researchers, students, and plant breeders to enhance traits like quality, yield, and disease resistance.
Article
Acoustics
Xueli He, Honglei Zhao, Yongxia Xu, Shumin Yi, Jianrong Li, Xuepeng Li
Summary: The effect of oat beta-glucan (OG) combined with ultrasound treatment on the gelation properties of silver carp surimi with different salt contents was investigated. The results showed that the addition of OG or ultrasound treatment significantly improved the texture properties, gel strength, and water holding capacity (WHC) of gel samples, regardless of salt contents. The combined treatment of OG and ultrasound demonstrated synergic action and produced superior gel properties compared to traditional heating method.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Engineering, Environmental
Hoang S. H. Nguyen, Malte Kaspereit, Tuomo Sainio
Summary: An integrated reactor-separator system was studied for the depolymerization of oat beta-glucan polysaccharide, aiming to produce oligosaccharides within a specific degree of polymerization range. Intermittent operation of the reactor led to higher yield and product purity compared to batch reactors. The experiments and simulations introduced dimensionless operating parameters and design considerations for analyzing performance of intermittent reactor-separators.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Applied
Thoa T. L. Nguyen, Bernadine M. Flanagan, Keyu Tao, Dongdong Ni, Michael J. Gidley, Glen P. Fox, Robert G. Gilbert
Summary: The inclusion of oats in white wheat salted noodles can lead to a slower digestion rate, potentially offering health benefits. The process of noodle-making and subsequent cooking affects the concentration and solubility of oat beta-glucan, impacting starch digestibility. This study suggests that interaction between beta-glucan and protein alters noodle microstructure, influencing digestibility.
Article
Biochemistry & Molecular Biology
Davide Risso, Gillian Dunngalvin, Sameer Saxena, Andrea Doolan, Lisa Spence, Kavita Karnik
Summary: This study investigated the gastrointestinal tolerance of low-calorie sugar D-allulose in young children and found that it was well tolerated. It can be considered as a candidate for replacing added sugars with lower caloric content in commercially produced goods.
Article
Biochemistry & Molecular Biology
Xinying Suo, Anna Baggio, Nicoletta Pellegrini, Silvia Vincenzetti, Elena Vittadini
Summary: This study investigated the effects of shape, gluten, and structural breakdown on the starch digestibility and glycemic index of gluten-containing and gluten-free pasta. The results showed that mastication effort, shape, and gluten content had significant impacts on starch digestion and glycemic index, with gluten being the major factor affecting the amount of digested starch.
Article
Biochemistry & Molecular Biology
Xinnuo Hu, Yanjun Yang, Cuihua Chang, Junhua Li, Yujie Su, Luping Gu
Summary: Fish collagen was enzymatically hydrolyzed using alkaline, papain, and ginger protease. The addition of ginger protease increased the degree of hydrolysis and resulted in changes in the amino acid composition and molecular weight distribution of the peptides. Combined hydrolysis with ginger protease improved the ACE inhibitory activity of the sample but affected fibroblast proliferation activity.
Article
Biochemistry & Molecular Biology
Tong Nie, Xin Wang, Aqun Li, Anshan Shan, Jun Ma
Summary: This study investigated the mechanism by which hesperidin prevents nonalcoholic fatty liver disease (NAFLD) by modulating fatty acid beta oxidation. The results suggest that hesperidin promotes fatty acid beta oxidation by activating SIRT1/PGC1 alpha, thus improving NAFLD.
Article
Biochemistry & Molecular Biology
Li Li, Jing Zhao, Jinxue Wang, Qianqian Xiong, Xuechun Lin, Xiaolei Guo, Fan Peng, Wangqun Liang, Xuezhi Zuo, Chenjiang Ying
Summary: The daily administration of 10 g d-1 inulin-type fructans significantly reduced the circulating arsenic retention in end-stage renal disease by increasing the arsenic clearance rate through urine and dialysis. However, it was found to be ineffective for other trace elements.
Article
Biochemistry & Molecular Biology
Chuanchuan Wang, Weixuan Chen, Yishan Jiang, Xiao Xiao, Qianhui Zou, Jiarui Liang, Yu Zhao, Qianxu Wang, Tian Yuan, Rui Guo, Xuebo Liu, Zhigang Liu
Summary: Autism Spectrum Disorder (ASD) symptoms may be improved through modulation of gut microbiota. This study investigated the effects of a synbiotic treatment on an ASD-like mouse model, and found that it rectified social impairments, attenuated inflammatory cytokine expressions, protected gut barrier integrity, and altered gut microbiota composition. The synbiotic treatment elevated beneficial metabolites and upregulated genes associated with their synthesis. Overall, the synbiotic combination mitigated ASD-related social impairments through regulation of the gut-brain axis.
Review
Biochemistry & Molecular Biology
Chunli Kong, Caiping Duan, Yixuan Zhang, Yiying Wang, Zheng Yan, Sumei Zhou
Summary: This review critically discusses the physicochemical properties of bioactive molecules in kidney beans and focuses on the current knowledge of non-starch polysaccharide (NSP) structure and function on intestinal health and metabolism. It also provides suggestions for further investigation and development of NSPs as novel plant carbohydrate resources.
Article
Biochemistry & Molecular Biology
Fei Shen, Qianqian Wang, Sami Ullah, Ya Pan, Minjie Zhao, Jing Wang, Ming Chen, Fengqin Feng, Hao Zhong
Summary: This study investigated the peristalsis-promoting potential of Ligilactobacillus acidipiscis YJ5 and its underlying molecular mechanism in relieving constipation. The results showed that L. acidipiscis YJ5 intervention increased intestinal peristalsis in zebrafish and mouse models, reduced colonic aquaporin expression, repaired intestinal morphological damage, enhanced the colonic mucosal barrier, and reversed the gut microbiota structure. The positive effects of L. acidipiscis YJ5 were attributed to its metabolites such as malic acid and heliangin.
Article
Biochemistry & Molecular Biology
Zhuo Qu, Jiahui Tian, Jiachen Sun, Ying Shi, Jianqiang Yu, Wannian Zhang, Chunlin Zhuang
Summary: Smoking is the main risk factor for lung cancer, but garlic oil compound DATS shows potential as a chemopreventive agent. DATS can inhibit the carcinogenic effects of tobacco and regulate gut microbiota, as well as activate the PPAR-gamma pathway to suppress tumor growth.
Article
Biochemistry & Molecular Biology
Yanli Zhang, Jielun Hu, Yadong Zhong, Shuai Liu, Liandi Liu, Xinyi Mu, Chunhua Chen, Shenji Yang, Guohao Li, Duoduo Zhang, Xinru Huang, Jinrui Yang, Xiaojun Huang, Shuigen Bian, Shaoping Nie
Summary: The study found that different ratios of insoluble and soluble dietary fiber have distinct effects on gut microbiota and serum metabolites. Increasing the ratio of insoluble dietary fiber increases the relative abundance and acid production of specific bacterial genera, while increasing the ratio of soluble dietary fiber increases the diversity and relative abundance of other bacterial genera and regulates metabolic pathways.
Article
Biochemistry & Molecular Biology
Enhui Tang, Tong Hu, Zhaokang Jiang, Xiaojun Shen, Huan Lin, Haiyan Xian, Xinlan Wu
Summary: Isoquercitrin alleviates lipopolysaccharide-induced intestinal mucosal barrier damage in mice by inhibiting the TLR4/MyD88/NF-kappa B signaling pathway and modulating the intestinal flora.
Article
Biochemistry & Molecular Biology
Nesma A. Abd Elrazik, Sahar A. Helmy
Summary: This study found that betanin, the major pigment in red beetroot, has a protective effect against bleomycin-induced pulmonary fibrosis in rats. The protective effect may be attributed to the attenuation of the NLRP3/IL-1 beta/TGF-beta 1 signaling pathway and the suppression of the EMT process.
Article
Biochemistry & Molecular Biology
Sha Li, Longchen Shang, Yuanyuan Chen, Rong Song, Jing Li, Bin Li
Summary: A new form of konjac fiber was prepared that could instantly expand in contact with digestive fluid, inhibiting the digestion of food. The digestion regulation ability of the fiber was influenced by the freezing temperature used during preparation, with the fiber prepared at -20 degrees C showing the best performance in delaying gastric emptying and preventing intestinal starch hydrolysis.
Article
Biochemistry & Molecular Biology
Xian Xia, Jiangdong Li, Rui Liang, Yi Li, Xiaojuan Ma, Ying Yang, Daniel Lozano-Ojalvo
Summary: This study aimed to reduce the allergenicity of ovomucoid through unfolding-assisted glycation. The results showed that maltose glycation effectively reduced the IgG-binding capacity of the allergen. Unfolded and glycated ovomucoid exhibited enhanced antioxidant activity and metal ion chelating ability.