Article
Medicine, General & Internal
Hideki Kobara, Kunihisa Uchita, Noriya Uedo, Jun Kunikata, Kenji Yorita, Naoya Tada, Noriko Nishiyama, Yuriko Shigehisa, Chihiro Kuroiwa, Noriko Matsuura, Yohei Takahashi, Yuka Kai, Uiko Hanaoka, Yumiko Kiyohara, Shoji Kamiura, Kenji Kanenishi, Tsutomu Masaki, Koki Hirano
Summary: This multicenter prospective study aimed to investigate the diagnostic ability of magnifying endoscopy with narrow band imaging (ME-NBI) for cervical intraepithelial neoplasia grade 2 or worse (CIN2+). The study found that ME-NBI exhibited a better sensitivity than colposcopy in detecting CIN2+ lesions, while also demonstrating a higher patient acceptability.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Oncology
Denisse Champin, Max Carlos Ramirez-Soto, Javier Vargas-Herrera
Summary: Smartphone images taken after a visual inspection with acetic acid (VIA) are more sensitive in detecting cervical intraepithelial neoplasia compared to other methods, improving diagnostic accuracy. However, the sensitivity and specificity of smartphones in detecting uterine cervical lesions are still limited.
Article
Agriculture, Dairy & Animal Science
Alba Marti, Anna Serrano, Josep Pastor, Teresa Rigau, Ugne Petkeviciute, Maria Angels Calvo, Esteban Leonardo Arosemena, Aida Yuste, David Prandi, Adria Aguilar, Maria Montserrat Rivera del Alamo
Summary: The study demonstrated that cytology may be a useful diagnostic tool for assessing the endometrial status in feline queens. The uterine lavage method was found to be more representative than uterine swabbing. Utilizing histopathological and bacteriological information further confirmed the diagnostic value of cytology in evaluating the endometrial health of feline queens.
Article
Obstetrics & Gynecology
Roisin Mulholland, Hazem M. S. A. Yousef, Margaret Laing, Rachana Gupta, Elaine Y. L. Leung
Summary: This study compared the clinical characteristics and outcomes of patients with different types of cervical glandular neoplasms, finding significant differences between those with non-cervical (NC) and endocervical (EC) neoplasms in terms of age, body mass index, symptoms, cancer incidence, and mortality. The results emphasize the importance of prompt and thorough investigations and treatments for these patients.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2021)
Article
Medicine, General & Internal
Kunihisa Uchita, Hideki Kobara, Kenji Yorita, Yuriko Shigehisa, Chihiro Kuroiwa, Noriko Nishiyama, Yohei Takahashi, Yuka Kai, Jun Kunikata, Toshio Shimokawa, Uiko Hanaoka, Kenji Kanenishi, Tsutomu Masaki, Koki Hirano, Noriya Uedo
Summary: The study investigated the feasibility of targeted endoscopic forceps biopsy (E-Bx) guided by ME-NBI for diagnosing CIN, showing that the proportion of sufficient samples with E-Bx was similar to that with traditional P-Bx, and had high sensitivity, specificity, and accuracy. Further investigation of the diagnostic accuracy of ME-NBI-guided E-Bx samples for CIN is warranted.
Article
Oncology
Yuki Nitta, Hiroto Murata, Noriyuki Okonogi, Kazutoshi Murata, Masaru Wakatsuki, Kumiko Karasawa, Shingo Kato, Shigeru Yamada, Takashi Nakano, Hiroshi Tsuji
Summary: This retrospective study assessed the incidence of secondary cancers in patients with cervical cancer who received carbon-ion radiotherapy (CIRT) and photon radiotherapy (RT). The results showed that the incidence of secondary cancers was similar between the two treatment groups.
Article
Radiology, Nuclear Medicine & Medical Imaging
Kari S. Wagner-Larsen, Njal Lura, Oyvind Salvesen, Mari Kylleso Halle, David Forsse, Jone Trovik, Noeska Smit, Camilla Krakstad, Ingfrid S. Haldorsen
Summary: The study evaluated the interobserver agreement and prognostic value of MRI-based 2018 FIGO staging parameters in cervical cancer patients. The results showed substantial agreement among radiologists for these parameters, and MRI improved the identification of patients with aggressive clinicopathological features and poor survival.
EUROPEAN RADIOLOGY
(2022)
Article
Medicine, Research & Experimental
Anna Angela Criscuolo, Francesco Sesti, Emilio Piccione, Pasquale Mancino, Elena Belloni, Cetty Gullo, Marco Ciotti
Summary: The Coriolus versicolor-based vaginal gel is proven to be both safe and effective in treating high-risk HPV infection, based on various tests including HPV DNA, colposcopy, and cytology. No adverse events were reported during the study.
ADVANCES IN THERAPY
(2021)
Article
Oncology
Mateja Condic, Claudio Neidhoefer, Damian J. Ralser, Nina Wetzig, Ralf Thiele, Martin Sieber, Lucia A. Otten, Leonie K. Warwas, Achim Hoerauf, Alexander Mustea, Marijo Parcina
Summary: This study evaluated the new cervical cancer screening program in Germany for the detection of high-grade cervical cancer precursor lesions and explored the potential impact of the cervico-vaginal microbiome on cervical dysplasia. The results showed a low rate of additional CIN III detected with the new screening program and confirmed the association between Ureaplasma parvum infection and histological abnormalities.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Oncology
Guanglei Zhong, Yuhan Wang, Qingsheng Xie, Rongchun Lin, Tingting Yao
Summary: HPV-16, 31, 33 and 58 infections are significant risk factors for cervical lesions. Combined HPV genotypes test can effectively predict cytological abnormalities.
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-Chun Lin, Yenpo Lin, Yen-Ling Huang, Chih-Yi Ho, Hsin-Ju Chiang, Hsin-Ying Lu, Chun-Chieh Wang, Jiun-Jie Wang, Shu-Hang Ng, Chyong-Huey Lai, Gigin Lin
Summary: This study investigates the generalizability of transfer learning for automated tumor segmentation in diffusion-weighted magnetic resonance imaging (DWI) of cervical and uterine malignancies. A pretrained model was established using data from cervical cancer patients, and transfer learning experiments were conducted. The results show that transfer learning can improve tumor segmentation performance for cervical and uterine malignancies.
INSIGHTS INTO IMAGING
(2023)
Review
Obstetrics & Gynecology
Hernan Dario Vargas-Cardona, Merida Rodriguez-Lopez, Marcela Arrivillaga, Carlos Vergara-Sanchez, Juan P. Garcia-Cifuentes, Paula C. Bermudez, Andres Jaramillo-Botero
Summary: This study describes and synthesizes the literature on the diagnostic accuracy of artificial intelligence (AI) in early imaging diagnosis of cervical cancer. The results show that the use of AI in cervical cancer screening has increased over the years, and some promising results have been achieved, especially in the field of deep learning.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Yang Liu, Jing Liao, Xiaojia Yi, Zhengmei Pan, Jing Pan, Chunyi Sun, Honglin Zhou, Yushi Meng
Summary: This study found that colposcopy has a moderate diagnostic accuracy in patients with HR-HPV-positive cytology-negative screening results. HPV viral load and childbearing history are independent factors affecting the accuracy of colposcopy-based diagnosis.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2022)
Article
Medicine, General & Internal
Deanna Teoh, Gwiwon Nam, Danielle A. Aase, Ruby Russell, Genevieve B. Melton, Shalini Kulasingam, Rachel I. Vogel
Summary: This study aimed to evaluate whether HPV vaccination is associated with decreased positive predictive value (PPV) for abnormal cervical cytology. The study found that among vaccinated individuals, the PPV for CIN 2 or more severe diagnosis was indeed lower compared to unvaccinated individuals. Additionally, among individuals who completed all vaccination doses, the PPV was lower than those with incomplete vaccination, especially among those who initiated vaccination when younger than 21 years.
Article
Obstetrics & Gynecology
Rosekeila Simoes Nomelini, Samela Daiere Soares Mota, Eddie Fernando Candido Murta
Summary: In this study, the association between band neutrophil count and overall survival in patients with invasive cervical cancer was evaluated. Band neutrophil count greater than 273/mm(3) was found to be a potential predictor of shorter overall survival, suggesting its clinical utility.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2022)