Article
Oncology
Jian Zhou, Huichuan Sun, Zheng Wang, Wenming Cong, Mengsu Zeng, Weiping Zhou, Ping Bie, Lianxin Liu, Tianfu Wen, Ming Kuang, Guohong Han, ZhiPing Yan, Maoqiang Wang, Ruibao Liu, Ligong Lu, Zhenggang Ren, ZhaoChong Zeng, Ping Liang, Changhong Liang, Min Chen, Fuhua Yan, Wenping Wang, Jinlin Hou, Yuan Ji, Jingping Yun, Xueli Bai, Dingfang Cai, Weixia Chen, Yongjun Chen, Wenwu Cheng, Shuqun Cheng, Chaoliu Dai, Wenzhi Guo, Yabing Guo, Baojin Hua, Xiaowu Huang, Weidong Jia, Qiu Li, Tao Li, Xun Li, Yaming Li, Yexiong Li, Jun Liang, Changquan Ling, Tianshu Liu, Xiufeng Liu, Shichun Lu, Guoyue Lv, Yilei Mao, Zhiqiang Meng, Tao Peng, Weixin Ren, Hongcheng Shi, Guoming Shi, Ming Shi, Tianqiang Song, Kaishan Tao, Jianhua Wang, Kui Wang, Lu Wang, Wentao Wang, Xiaoying Wang, Zhiming Wang, Bangde Xiang, Baocai Xing, Jianming Xu, Jiamei Yang, Jianyong Yang, Yefa Yang, Yunke Yang, Shenglong Ye, Zhenyu Yin, Yong Zeng, Bixiang Zhang, Boheng Zhang, Leida Zhang, Shuijun Zhang, Ti Zhang, Yanqiao Zhang, Ming Zhao, Yongfu Zhao, Honggang Zheng, Ledu Zhou, Jiye Zhu, Kangshun Zhu, Rong Liu, Yinghong Shi, Yongsheng Xiao, Lan Zhang, Chun Yang, Zhifeng Wu, Zhi Dai, Minshan Chen, Jianqiang Cai, Weilin Wang, Xiujun Cai, Qiang Li, Feng Shen, Shukui Qin, Gaojun Teng, Jiahong Dong, Jia Fan
Summary: With the emergence of additional high-quality evidence worldwide, the Chinese guidelines for the diagnosis and treatment of primary liver cancer need to be updated again. The new edition, written by over 100 experts in the field, aims to encourage evidence-based practice and improve the national average five-year survival rate for liver cancer patients, in line with the Health China 2030 Blueprint.
Review
Oncology
P. Queirolo, M. Cinquini, G. Argenziano, F. Bassetto, P. Bossi, A. Boutros, C. Clemente, V. de Giorgi, M. Del Vecchio, R. Patuzzo, K. Peris, P. Quaglino, A. Reali, I. Zalaudek, F. Spagnolo
Summary: Basal cell carcinoma (BCC) is a common form of cancer with significant impact on public health and social costs. While overall prognosis for BCC patients is usually excellent, certain cases may require challenging treatments. Guidelines for diagnosis, treatment, and follow-up, including systemic treatments when necessary, have been developed to improve patient care.
Article
Oncology
R. Kanesvaran, C. Porta, A. Wong, T. Powles, Q. S. Ng, M. Schmidinger, D. Ye, H. Malhotra, Y. Miura, J. L. Lee, F. L. T. Chong, Y-S Pu, C-C Yen, M. Saad, H. J. Lee, H. Kitamura, G. S. Bhattacharyya, G. Curigliano, E. Poon, S. P. Choo, S. Peters, E. Lim, T. Yoshino, G. Pentheroudakis
Summary: The ESMO and SSO held a special virtual guidelines meeting in May 2021 to adapt the 2019 guidelines for renal cell carcinoma treatment to account for ethnic differences in Asian patients. Expert opinions from oncological societies in China, India, Japan, Korea, Malaysia, Singapore, and Taiwan were considered based on scientific evidence independent of current treatment practices and drug access restrictions in Asian countries.
Review
Immunology
Ting Gu, Wen Li, Li-Li Yang, Si-Min Yang, Qian He, Hai-Yu He, Da-Li Sun
Summary: This study systematically assessed the methodological quality of guidelines for the diagnosis and treatment of Clostridioides difficile infection (CDI) and found that the quality varied. The recommendations for the diagnosis and treatment of CDI in the guidelines were heterogeneous, with some recommendations lacking evidence and relying on low-level evidence. There is also a lack of unified classification criteria for the severity of CDI. Guideline developers need to improve these factors to further update the guidelines.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Clinical Neurology
Charles M. Morin, Yuchi Inoue, Clete Kushida, Dalva Poyares, John Winkelman
Summary: The European guideline for the diagnosis and treatment of insomnia was developed by a task force of the European Sleep Research Society, focusing on recommendations for the treatment of chronic insomnia disorder as defined by ICD-10/ICSD-3. The guideline was revised and expanded based on relevant meta-analyses of insomnia therapies published through June 2016, and has been reviewed by the World Sleep Society and International Sleep Medicine Guidelines Committee for relevance and applicability to sleep specialists' practice.
Article
Oncology
B. Keam, J-P Machiels, H. R. Kim, L. Licitra, W. Golusinski, V Gregoire, Y. G. Lee, C. Belka, Y. Guo, S. J. Rajappa, M. Tahara, M. Azrif, M. K. Ang, M-H Yang, C-H Wang, Q. S. Ng, W. I. Wan Zamaniah, N. Kiyota, S. Babu, K. Yang, G. Curigliano, S. Peters, T. W. Kim, T. Yoshino, G. Pentheroudakis
Summary: ESMO and KSMO convened a special virtual guidelines meeting in July 2021 to adapt the ESMO 2020 guidelines to consider potential ethnic differences in Asian patients' treatment of SCCs of the head and neck. These guidelines represent consensus opinions from experts across Asia and provide expert recommendations for the diagnosis, treatment, and management of patients with SCC of the oral cavity, larynx, oropharynx, and hypopharynx.
Review
Oncology
Xiao-Feng Yang, Meng-Yao Zheng, Li-Ya An, Jin-Min Sun, Qian-Wen Hei, Yan-Hong Ji, Da-Li Sun, Hai-Yu He
Summary: This study systematically evaluated guidelines for the diagnosis and treatment of radioactive enteritis, compared their differences and reasons, and provided reference for updating them. Six guidelines were included, and the American Society for Gastrointestinal Endoscopy guidelines had an overall score of over 60%, which is worthy of clinical recommendation. The recommendations for endoscopic treatment of radioactive rectal injury are mature, with several methods available.
RADIATION ONCOLOGY
(2023)
Article
Oncology
Arthur Petat, Eric Dansin, Fabien Calcagno, Laurent Greillier, Eric Pichon, Mallorie Kerjouan, Christelle Clement-Duchene, Bertrand Mennecier, Virginie Westeel, Francois Thillays, Xavier Quantin, Youssef Oulkhouir, Luc Thiberville, Charles Ricordel, Vincent Thomas De Montpreville, Lara Chalabreysse, Veronique Hofman, Thierry Molina, Pierre Fournel, Laurence Bigay Game, Benjamin Besse, Nicolas Girard
Summary: This study utilized the RYTHMIC database to analyze baseline characteristics, treatment strategies, and outcomes of patients with thymic carcinoma, highlighting the need for optimized multidisciplinary management and innovative therapies.
EUROPEAN JOURNAL OF CANCER
(2022)
Article
Oncology
Ketty Peris, Maria Concetta Fargnoli, Roland Kaufmann, Petr Arenberger, Lars Bastholt, Nicole Basset Seguin, Veronique Bataille, Lieve Brochez, Veronique del Marmol, Reinhard Dummer, Ana-Marie Forsea, Caroline Gaudy-Marqueste, Catherine A. Harwood, Axel Hauschild, Christoph Hoeller, Lidija Kandolf, Nicole W. J. Kellerners-Smeets, Aimilios Lallas, Ulrike Leiter, Josep Malvehy, Branka Marinovic, Zeljko Mijuskovic, David Moreno-Ramirez, Eduardo Nagore, Paul Nathan, Alexander J. Stratigos, Eggert Stockfleth, Luca Tagliaferri, Myrto Trakatelli, Ricardo Vieira, Iris Zalaudek, Claus Garbe, EADO, EDF, ESTRO, UEMS, V EAD
Summary: Basal cell carcinoma is the most common malignant tumor in white populations. This article provides updated recommendations on the diagnosis and treatment of BCC, including classification, surgical treatment, topical therapies, and the use of hedgehog inhibitors and immunotherapy. Regular skin examinations and long-term follow-up are also recommended for high-risk patients.
EUROPEAN JOURNAL OF CANCER
(2023)
Review
Oncology
Callum J. R. Mullen, Ronald D. Barr, Eduardo L. Franco
Summary: Cancer is a significant cause of disease-related death in children globally, but advancements in treatment and understanding have improved survival rates. Factors at individual, community, and systemic levels can impact childhood cancer experiences, yet risk-based surveillance programs have shown promise in enhancing outcomes.
BRITISH JOURNAL OF CANCER
(2021)
Review
Gastroenterology & Hepatology
Wattana Leowattana, Pathomthep Leowattana, Tawithep Leowattana
Summary: Esophageal cancer is a prevalent malignancy with poor survival rates. Neoadjuvant chemoradiotherapy combined with surgery is the standard treatment, but it has limited effectiveness. Recent advancements in immunotherapy have shown potential in increasing the survival of resectable esophageal cancer patients. Combining chemotherapy, radiation, and immunotherapy may have a synergistic antitumor effect. This review discusses the rationale, clinical outcomes, ongoing investigations, and research requirements for neoadjuvant immunotherapy in resectable esophageal cancer patients.
WORLD JOURNAL OF GASTROENTEROLOGY
(2023)
Review
Medicine, General & Internal
Maja Mejza, Ewa Malecka-Wojciesko
Summary: Barrett's esophagus is a precancerous condition of the esophagus, characterized by a salmon-colored lining and the presence of columnar epithelium with goblet cells. It is associated with esophageal adenocarcinoma, a tumor with poor survival rates and increasing incidence. The diagnosis and management of Barrett's esophagus remain a topic of ongoing debate. This article provides an overview of current recommendations and new discoveries in this field.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Cell Biology
Adrian Vasile Dumitru, Dana Antonia Tapoi, Georgian Halcu, Octavian Munteanu, David-Ioan Dumitrascu, Mihail Constantin Ceausu, Ancuta-Augustina Gheorghisan-Galateanu
Summary: CD30, a glycosylated protein receptor, acts as a tumor marker found on the surface of certain cells. This receptor plays a critical role in diagnosing various diseases, including Hodgkin lymphoma, embryonal carcinoma, anaplastic large cell lymphoma, and cutaneous T-cell lymphoma. In addition to its diagnostic significance, CD30-targeted therapies show promising potential for treating CD30-positive lymphomas and autoimmune disorders.
Article
Surgery
Hamed Gheibollahi, Amirreza Dehghanian, Negar Taheri, Saeid Tavanafar, Seyede Sona Mousavi, Hamidreza Abbasi, Mohammadreza Sasani
Summary: Esophageal leiomyosarcoma (LMS) and squamous cell carcinoma (SCC) occurring concurrently is extremely rare, as presented in a case of a 64-year-old woman with symptoms of vomiting and solid dysphagia. Surgery was performed for diagnosis, highlighting the importance of ancillary diagnostic tests such as immunohistochemistry (IHC) for less common cases.
Article
Engineering, Biomedical
Shasha Shi, Huipu Li, Xi Zheng, Lin Lv, Shengtao Liao, Peng Lu, Maoxia Liu, Hongyun Zhao, Zhechuan Mei
Summary: This article introduces a visual diagnosis and treatment system based on hierarchical targeting, which improves the drug enrichment rate and treatment accuracy through biomagnetic-mediated primary targeting and antibody-mediated secondary targeting. The combination of low intensity focused ultrasound irradiation and released interferon gamma and its receptor allows for physical damage to liver cancer stem cells and the initiation of chemotherapy and immunotherapy.
MATERIALS TODAY BIO
(2022)
