Article
Psychology, Developmental
Emma Sciberras, Pooja Patel, Mark A. Stokes, David Coghill, Christel M. Middeldorp, Mark A. Bellgrove, Stephen P. Becker, Daryl Efron, Argyris Stringaris, Stephen V. Faraone, Susannah T. Bellows, Jon Quach, Tobias Banaschewski, Jane McGillivray, Delyse Hutchinson, Tim J. Silk, Glenn Melvin, Amanda G. Wood, Anna Jackson, George Loram, Lidia Engel, Alicia Montgomery, Elizabeth Westrupp
Summary: The study found that COVID-19 restrictions had negative impacts on children with ADHD, leading to reduced physical activity and outdoor time, decreased enjoyment in activities, and increased screen time and negative emotions. However, some parents reported positive changes in their children, such as increased family time during this period.
JOURNAL OF ATTENTION DISORDERS
(2022)
Article
Psychology, Developmental
Ann C. Childress, Henry C. Foehl, Jeffrey H. Newcorn, Stephen Faraone, Benjamin Levinson, Akwete L. Adjei
Summary: The study on the long-term safety and symptom control of extended-release methylphenidate in children aged 4 to <6 years showed that most treatment-emergent adverse events were of mild or moderate severity, weight and height z scores as well as obesity rates decreased significantly, with insomnia reported in 9% and hypertension in 6.7%, while ADHD symptom control was maintained.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2022)
Article
Psychology, Developmental
Corentin J. Gosling, Samuele Cortese, Eric Konofal, Michel Lecendreux, Stephen V. Faraone
Summary: This study examined the association between sleep disturbances and ADHD symptoms over a 9-year period, finding that sleep disturbances at age 13 predicted increased ADHD symptoms at age 18, while ADHD symptoms at age 9 predicted increased sleep disturbances at age 13. The findings highlight the importance of identifying these issues for preventive interventions.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Review
Biochemistry & Molecular Biology
Alessio Bellato, John Perna, Preethi S. Ganapathy, Marco Solmi, Andrea Zampieri, Samuele Cortese, Stephen Faraone
Summary: This study conducted a systematic review and meta-analysis to investigate the association between attention-deficit/hyperactivity disorder (ADHD) and eye disorders as well as altered visual function. The findings suggest that ADHD is associated with an increased risk of certain vision problems and visual function impairments, but not with structural changes in the eye.
MOLECULAR PSYCHIATRY
(2023)
Review
Biochemistry & Molecular Biology
Angelica Varesi, Salvatore Chirumbolo, Lucrezia Irene Maria Campagnoli, Elisa Pierella, Gaia Bavestrello Piccini, Adelaide Carrara, Giovanni Ricevuti, Catia Scassellati, Cristian Bonvicini, Alessia Pascale
Summary: Cellular senescence is an irreversible state of cell cycle arrest caused by various stressful stimuli. Oxidative stress plays a crucial role in driving senescence. Identifying and characterizing antioxidant compounds that can prevent or counteract senescence is of great interest, but a comprehensive overview is currently lacking.
Article
Psychiatry
Stephen V. Faraone, Roberto Gomeni, Joseph T. Hull, Soumya A. Chaturvedi, Gregory D. Busse, Zare Melyan, Welton O'Neal, Jonathan Rubin, Azmi Nasser
Summary: Early response to viloxazine ER treatment predicts efficacy outcome in ADHD patients, and the predictive model is consistent across different age groups.
PSYCHIATRY RESEARCH
(2022)
Article
Psychology, Developmental
Yanli Zhang-James, Ali Shervin Razavi, Martine Hoogman, Barbara Franke, Stephen V. Faraone
Summary: This systematic review examines the literature on the development of magnetic resonance imaging (MRI)-based diagnostic classifiers for attention-deficit/hyperactivity disorder (ADHD) using machine learning (ML). It found variations in MRI modalities, ML models, cross-validation and testing methods, and sample sizes among the studies. The review also highlights the importance of large multi-modal imaging datasets and the potential combination with other types of data to develop clinically useful imaging classification tools for ADHD in the future.
JOURNAL OF ATTENTION DISORDERS
(2023)
Article
Psychiatry
Mai Uchida, Qasim Bukhari, Maura DiSalvo, Allison Green, Giulia Serra, Chloe Hutt Vater, Satrajit S. Ghosh, Stephen V. Faraone, John D. E. Gabrieli, Joseph Biederman
Summary: This study developed a quantitative predictive model for bipolar disorder using machine learning algorithms and clinical data. The predictors included behavioral problems, school functioning, and anxiety/depression and aggression scales. The results have important clinical and scientific implications for assessing the risk of bipolar disorder in children.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Biographical-Item
Neurosciences
Stephen V. Faraone
BIOLOGICAL PSYCHIATRY
(2023)
Review
Clinical Neurology
Nevena V. Radonjic, Alessio Bellato, Nayla M. Khoury, Samuele Cortese, Stephen V. Faraone
Summary: This study conducted a systematic review and meta-analysis to assess the efficacy, acceptability, and tolerability of nonstimulants in adults with ADHD. The results showed that atomoxetine, guanfacine, and viloxazine ER were significantly more effective than placebo in treating ADHD. However, atomoxetine had poorer tolerability compared to placebo.
Article
Psychology, Developmental
Elisabeth F. Callen, Tarin L. Clay, Jillian Alai, David W. Goodman, Lenard A. Adler, Joel Shields, Stephen V. Faraone
Summary: This study aimed to assess the changes in quality care for adults with ADHD from 2010 to 2020. The results showed an increase in the achievement of quality measures over time, but none of the patients achieved more than six out of ten measures in any year. Small but significant effects were observed for sex, race, ethnicity, practice ownership, practice type, and age.
JOURNAL OF ATTENTION DISORDERS
(2023)
Article
Endocrinology & Metabolism
Ali Zare Dehnavi, Yanli Zhang-James, Dan Draytsel, Ben Carguello, Stephen V. Faraone, Ruth S. Weinstock
Summary: This study found that approximately 49.2% of adults with type 2 diabetes (T2D) met the diagnostic criteria for attention-deficit/hyperactivity disorder (ADHD). However, there was no direct association between these symptoms and cardiovascular diseases or diabetic control. Further research is needed to clarify the relationship between ADHD symptoms, diabetic control, and comorbidities.
JOURNAL OF CLINICAL AND TRANSLATIONAL ENDOCRINOLOGY
(2023)
Review
Biochemistry & Molecular Biology
John Perna, Alessio Bellato, Preethi S. Ganapathy, Marco Solmi, Andrea Zampieri, Stephen V. Faraone, Samuele Cortese
Summary: This study conducted a systematic review and meta-analysis to investigate the association between vision and/or eye disorders and Autism Spectrum Disorder (ASD). The findings suggest that ASD is associated with functional vision problems and structural alterations of the eye. However, further research is needed to clarify the causal relationship between ASD and vision problems.
MOLECULAR PSYCHIATRY
(2023)
Correction
Biochemistry & Molecular Biology
John Perna, Alessio Bellato, Preethi S. Ganapathy, Marco Solmi, Andrea Zampieri, Stephen V. Faraone, Samuele Cortese
MOLECULAR PSYCHIATRY
(2023)
Review
Pharmacology & Pharmacy
Lisa O'Connor, Stephanie Carbone, Anthony Gobbo, Hilary Gamble, Stephen Faraone
Summary: This article provides an overview of pharmacological treatment options for pediatric attention-deficit disorder (ADHD), including stimulant and non-stimulant medications. It offers detailed information on new medication options, such as anesthetic agents, extended-release forms, and novel adjunctive medications. These additions are beneficial for clinicians in their treatment toolbox.
EXPERT REVIEW OF CLINICAL PHARMACOLOGY
(2023)