Article
Psychiatry
Elizabeth A. Martin, Katherine G. Jonas, Wenxuan Lian, Dan Foti, Kayla R. Donaldson, Evelyn J. Bromet, Roman Kotov
Summary: The HiTOP dimensional approach showed greater predictive power in long-term outcomes of psychotic disorders compared to traditional DSM diagnoses, across various aspects including psychiatric and physical health, community functioning, and neural responses.
SCHIZOPHRENIA BULLETIN
(2021)
Article
Medicine, General & Internal
Markku Lahteenvuo, Ari Ahola-Olli, Kimmo Suokas, Minna Holm, Zuzanna Misiewicz, Tuomas Jukuri, Teemu Maennynsalo, Asko Wegelius, Willehard Haaki, Risto Kajanne, Aija Kyttala, Annamari Tuulio-Henriksson, Kaisla Lahdensuo, Katja Hakkinen, Jarmo Hietala, Tiina Paunio, Jussi Niemi-Pynttari, Tuula Kieseppa, Juha Veijola, Jouko Lonnqvist, Erkki Isometsa, Olli Kampman, Jari Tiihonen, Steven Hyman, Benjamin Neale, Mark Daly, Jaana Suvisaari, Aarno Palotie
Summary: The purpose of this study is to establish a large Finnish collection of psychosis cases, including diverse populations from Asia, Latin America, and Africa, in addition to known population isolates like Finland. A total of 10,474 individuals aged 18 years or older were recruited and genotyped. The future plans of this study include investigating the effects of common variants, rare variants, and copy number variations on the severity of psychotic illness, as well as tracking the longitudinal course of illness based on nationwide register data.
Article
Psychiatry
Eberhard David, Billstedt Eva, Gillberg Christopher
Summary: Missed cases of neurodevelopmental disorders (NDDs) within adult psychiatry services have attracted increasing attention. This study found that almost two thirds of first-time attenders at an adult psychiatry clinic met criteria for ADHD or ASD. Most of the patients with NDD had not been diagnosed in childhood. The results underscore the importance of screening for NDD in adult psychiatric services.
PSYCHIATRY RESEARCH
(2022)
Article
Medicine, General & Internal
Lars Clemmensen, Gry Jorgensen, Kristina Ballestad Gundersen, Lisa Charlotte Smith, Julie Midtgaard, Stephane Bouchard, Christina Plambock Thomsen, Louise Turgut, Louise Birkedal Glenthoj
Summary: This study aims to investigate the effects and feasibility of using virtual reality (VR) as a recreational intervention for psychiatric inpatients. A mixed-methods clinical trial will be conducted with 124 patients, comparing outcomes for a period with VR-based experiences and a period without VR. Findings from this study will be disseminated through academic publications and presentations.
Article
Psychiatry
R. Oberndorfer, R. W. Alexandrowicz, A. Unger, M. Koch, I Markiewicz, P. Gosek, J. Heitzman, L. Iozzino, C. Ferrari, H-J Salize, M. Picchioni, H. Fangerau, T. Stompe, J. Wancata, G. de Girolamo
Summary: This study compared the frequency of needs of patients with schizophrenia in forensic services across five European countries. The results showed differences in the assessments of needs between patients and their care staff, with staff reporting more total needs and patients reporting more unmet needs. The findings suggest that patients' self-assessments of needs provide important information for providing sufficient help and support.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2023)
Article
Psychology, Clinical
Katie N. Sampson, Rachel Upthegrove, Ahmad Abu-Akel, Sayeed Haque, Stephen J. Wood, Renate Reniers
Summary: The study found a positive correlation between sub-clinical autistic and positive psychotic traits. Autistic traits and psychotic traits independently predict depression, self-harm, and suicidality. Interestingly, a negative interaction between the autistic trait of attention to detail and psychotic traits was associated with depression.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Alina Laskowski, Tania M. Lincoln
Summary: This planned network meta-analysis aims to compare the efficacy of different types of family interventions for psychotic disorders by looking at various content and format factors. Main outcomes will focus on patients' clinical state and relatives' attitudes towards psychosis, with additional measures including symptom severity, functioning, burden, and compliance/drop-out. This study will use a random effects model within a frequentist framework to rank interventions based on relative efficacy and address issues of transitivity, heterogeneity, and inconsistency.
Article
Psychiatry
Anastasia Lim, Jan Dirk Blom
Summary: A significant portion of Muslim psychiatric patients experience tactile and somatic hallucinations, often in a multimodal or full-blown entity/jinn encounter form, causing distress. The involvement of sensory modalities in these hallucinations may be related to an underlying stochastic process, as suggested by the research findings.
FRONTIERS IN PSYCHIATRY
(2021)
Review
Medicine, General & Internal
Jan Mei Lim, Joanna Barlas, Divjyot Kaur
Summary: The challenges of caregiving can have a significant impact on the emotional and psychological well-being of caregivers, including the development of post-traumatic stress symptoms. However, there is limited and unclear literature on PTSS among caregivers of individuals with neurodevelopmental, neurocognitive, and psychiatric disorders. This scoping review aims to map the existing research on PTSS in these caregivers, identifying key concepts and gaps in the literature.
Editorial Material
Psychiatry
Premal J. Shah, Marie Boilson, Marion Rutherford, Susan Prior, Lorna Johnston, Donald Maciver, Kirsty Forsyth
Summary: Research provides definitions of important terms related to neurodevelopmental disorders, aiming to enhance understanding and clinical practices within adult mental health services.
BRITISH JOURNAL OF PSYCHIATRY
(2022)
Article
Clinical Neurology
G. Fond, M. Faugere, R. Richieri, M. Cermolacce, T. Korchia, J. A. Micoulaud-Franchi, P. L. Sunhary de Verville, L. Boyer, C. Lancon
Summary: This study found that depressive symptoms and chronic peripheral inflammation are associated with impaired functional remission in patients with schizophrenia, independent of psychotic remission. These findings emphasize the potential of improving depressive symptoms and chronic peripheral inflammation to help patients achieve functional remission.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Medicine, General & Internal
Larry Alphs, Ibrahim Turkoz, Virginia Smith-Swintosky, Alexander Keenan, Emily Abraham, Alain Schotte, Eileen Hooker, Jean Damascene Iyamuremye, Yvonne Kayiteshonga, Rutakayile Bizoza, Branislav Mancevski
Summary: This study aimed to assess the feasibility of conducting a large clinical trial within the Rwandan mental healthcare system to determine the safety, efficacy, and benefits of paliperidone palmitate once-monthly (PP1M) and once-every-3-months (PP3M) long-acting injectable formulations in adults with schizophrenia. The study identified areas for improvement in study execution, but these limitations were considered surmountable.
Review
Psychiatry
Eva Rogers, Mark Gresswell, Simon Durrant
Summary: Individuals with Schizophrenia Spectrum Disorders (SSDs) have higher rates of suicidal thoughts, attempts, and death by suicide. Sleep disturbances are risk factors for suicidality and are also implicated in the onset and exacerbation of psychotic symptoms in SSDs. Sleep monitoring may offer an adjunct risk monitoring method and potential treatment target for SSDs. Further research is needed to explore the relationships between specific aspects of suicidality and objective sleep parameters, as well as the psychological processes underlying the sleep-suicide relationship in SSDs.
SCHIZOPHRENIA RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Naohiro Okada, Masaki Fukunaga, Kenichiro Miura, Kiyotaka Nemoto, Junya Matsumoto, Naoki Hashimoto, Masahiro Kiyota, Kentaro Morita, Daisuke Koshiyama, Kazutaka Ohi, Tsutomu Takahashi, Michihiko Koeda, Hidenaga Yamamori, Michiko Fujimoto, Yuka Yasuda, Naomi Hasegawa, Hisashi Narita, Satoshi Yokoyama, Ryo Mishima, Takahiko Kawashima, Yuko Kobayashi, Daiki Sasabayashi, Kenichiro Harada, Maeri Yamamoto, Yoji Hirano, Takashi Itahashi, Masahito Nakataki, Ryu-ichiro Hashimoto, Khin K. Tha, Shinsuke Koike, Toshio Matsubara, Go Okada, Theo G. M. van Erp, Neda Jahanshad, Reiji Yoshimura, Osamu Abe, Toshiaki Onitsuka, Yoshiyuki Watanabe, Koji Matsuo, Hidenori Yamasue, Yasumasa Okamoto, Michio Suzuki, Jessica A. Turner, Paul M. Thompson, Norio Ozaki, Kiyoto Kasai, Ryota Hashimoto
Summary: This article discusses the difficulties in differential diagnosis in practical psychiatric settings and the prospect of creating a novel diagnostic system using objective biomarkers. Neuroimaging studies have shown that subcortical brain structures are associated with various psycho-behavioral functions, but there are currently no neuroimaging data-driven clinical criteria that can overcome the limitations of the current diagnostic system in reflecting cognitive/social functioning. The authors conducted a large-scale study and found volumetric and lateralization alterations in several psychiatric disorders, which were associated with cognitive/social functioning.
MOLECULAR PSYCHIATRY
(2023)
Article
Psychiatry
Johan Nyrenius, Jonas Eberhard, Mohammad Ghaziuddin, Christopher Gillberg, Eva Billstedt
Summary: This study aims to investigate the characteristics of autism spectrum disorder (ASD) in adult psychiatric outpatients and compare them with non-ASD patients. The results showed that the ASD group had a higher number of co-occurring psychiatric disorders and lower functional level compared to the non-ASD group. This study emphasizes the importance of comprehensive assessment of psychiatric disorders in ASD patients in adult psychiatric services.
