Genetic Variation in the Epigenetic Machinery and Mental Health

Sex Difference in the Expression of DNA Methyltransferase 3a in the Rat Amygdala During Development

(2011) M. H. Kolodkin et al.   JOURNAL OF NEUROENDOCRINOLOGY

State-dependent changes in the expression of DNA methyltransferases in mood disorder patients

(2011) Fumihiro Higuchi et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Subregion-specific p300 conditional knock-out mice exhibit long-term memory impairments

(2011) A. M. M. Oliveira et al.   LEARNING & MEMORY

Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss

(2011) Christopher J Klein et al.   NATURE GENETICS

Identification of a novel CDKL5 exon and pathogenic mutations in patients with severe mental retardation, early-onset seizures and Rett-like features

(2011) Nils Rademacher et al.   NEUROGENETICS

Epigenetic Status of Gdnf in the Ventral Striatum Determines Susceptibility and Adaptation to Daily Stressful Events

(2011) Shusaku Uchida et al.   NEURON

A Role for Repressive Histone Methylation in Cocaine-Induced Vulnerability to Stress

(2011) Herbert E. Covington et al.   NEURON

Broad Epigenetic Signature of Maternal Care in the Brain of Adult Rats

(2011) Patrick O. McGowan et al.   PLoS One

Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcohol

(2011) Z. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MED23 Mutation Links Intellectual Disability to Dysregulation of Immediate Early Gene Expression

(2011) S. Hashimoto et al.   SCIENCE

Epigenetics of Early Child Development

(2011) Chris Murgatroyd et al.   Frontiers in Psychiatry

Haploinsufficiency of HDAC4 Causes Brachydactyly Mental Retardation Syndrome, with Brachydactyly Type E, Developmental Delays, and Behavioral Problems

(2010) Stephen R. Williams et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Sex-dependent behavioral effects of Mthfr deficiency and neonatal GABA potentiation in mice

(2010) Tamar Levav-Rabkin et al.   BEHAVIOURAL BRAIN RESEARCH

Reversibility of functional deficits in experimental models of Rett syndrome

(2010) Stuart Cobb et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Early Environmental Enrichment Moderates the Behavioral and Synaptic Phenotype of MeCP2 Null Mice

(2010) Giuseppina Lonetti et al.   BIOLOGICAL PSYCHIATRY

Meta-analysis of MTHFR gene variants in schizophrenia, bipolar disorder and unipolar depressive disorder: Evidence for a common genetic vulnerability?

(2010) Odette L.J. Peerbooms et al.   BRAIN BEHAVIOR AND IMMUNITY

Chromatin remodeling in neural stem cell differentiation

(2010) Berry Juliandi et al.   CURRENT OPINION IN NEUROBIOLOGY

CAMOS, a nonprogressive, autosomal recessive, congenital cerebellar ataxia, is caused by a mutant zinc-finger protein, ZNF592

(2010) Elsa Nicolas et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice

(2010) Tatsuya Nogami et al.   HIPPOCAMPUS

A mutation in the 3′-UTR of the HDAC6 gene abolishing the post-transcriptional regulation mediated by hsa-miR-433 is linked to a new form of dominant X-linked chondrodysplasia

(2010) Delphine Simon et al.   HUMAN MOLECULAR GENETICS

Maternal Care and DNA Methylation of a Glutamic Acid Decarboxylase 1 Promoter in Rat Hippocampus

(2010) T.-Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

CDKL5, a Protein Associated with Rett Syndrome, Regulates Neuronal Morphogenesis via Rac1 Signaling

(2010) Q. Chen et al.   JOURNAL OF NEUROSCIENCE

Clinical variations modulate patterns of gene expression and define blood biomarkers in major depression

(2010) Raoul Belzeaux et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome

(2010) Sarah B Ng et al.   NATURE GENETICS

MeCP2 and drug addiction

(2010) Jian Feng et al.   NATURE NEUROSCIENCE

Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

(2010) Quincey LaPlant et al.   NATURE NEUROSCIENCE

Clinical Genetic Testing for Patients With Autism Spectrum Disorders

(2010) Y. Shen et al.   PEDIATRICS

Human Intelligence and Polymorphisms in the DNA Methyltransferase Genes Involved in Epigenetic Marking

(2010) Paul Haggarty et al.   PLoS One

Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex

(2010) J. D. Pereira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of histone deacetylase genes with schizophrenia in Korean population

(2010) Tae Kim et al.   PSYCHIATRY RESEARCH

Sex differences in brain epigenetics

(2010) Yannick Menger et al.   Epigenomics

Reduced exploration, increased anxiety, and altered social behavior: Autistic-like features of euchromatin histone methyltransferase 1 heterozygous knockout mice

(2009) Monique C.M. Balemans et al.   BEHAVIOURAL BRAIN RESEARCH

The N-Myc-DLL3 Cascade Is Suppressed by the Ubiquitin Ligase Huwe1 to Inhibit Proliferation and Promote Neurogenesis in the Developing Brain

(2009) Xudong Zhao et al.   DEVELOPMENTAL CELL

The 2q23.1 microdeletion syndrome: clinical and behavioural phenotype

(2009) Bregje WM van Bon et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Identification of ANKRD11 and ZNF778 as candidate genes for autism and variable cognitive impairment in the novel 16q24.3 microdeletion syndrome

(2009) Marjolein H Willemsen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Haploinsufficiency of MBD5 associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment and seizures

(2009) Stephen R Williams et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

BCOR analysis in patients with OFCD and Lenz microphthalmia syndromes, mental retardation with ocular anomalies and cardiac laterality defects

(2009) Emma Hilton et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Epigenetic control of skull morphogenesis by histone deacetylase 8

(2009) M. Haberland et al.   GENES & DEVELOPMENT

Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndrome

(2009) W.S. Layman et al.   HUMAN MOLECULAR GENETICS

DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation

(2009) Leah K. Hutnick et al.   HUMAN MOLECULAR GENETICS

Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia

(2009) Minori Koga et al.   HUMAN MOLECULAR GENETICS

Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population

(2009) David P. Gavin et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Altered gene expression of histone deacetylases in mood disorder patients

(2009) Teruyuki Hobara et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Aberrant REST-mediated transcriptional regulation in major depressive disorder

(2009) Koji Otsuki et al.   JOURNAL OF PSYCHIATRIC RESEARCH

A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation

(2009) Patrick S Tarpey et al.   NATURE GENETICS

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

(2009) Patrick O McGowan et al.   NATURE NEUROSCIENCE

Dynamic DNA methylation programs persistent adverse effects of early-life stress

(2009) Chris Murgatroyd et al.   NATURE NEUROSCIENCE

Novel variants identified in methyl-CpG-binding domain genes in autistic individuals

(2009) Holly N. Cukier et al.   NEUROGENETICS

Control of Cognition and Adaptive Behavior by the GLP/G9a Epigenetic Suppressor Complex

(2009) Anne Schaefer et al.   NEURON

DNA methyltransferase 3B gene increases risk of early onset schizophrenia

(2009) Chen Zhang et al.   NEUROSCIENCE LETTERS

Site-specific regulation of cell cycle and DNA repair in post-mitotic GABA cells in schizophrenic versus bipolars

(2009) Francine M. Benes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development

(2009) R. L. Montgomery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes

(2009) A. Zhubi et al.   SCHIZOPHRENIA RESEARCH

Neuronal Activity-Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis

(2009) D. K. Ma et al.   SCIENCE

Evolving role of MeCP2 in Rett syndrome and autism

(2009) Janine M LaSalle et al.   Epigenomics

Submicroscopic Duplications of the Hydroxysteroid Dehydrogenase HSD17B10 and the E3 Ubiquitin Ligase HUWE1 Are Associated with Mental Retardation

(2008) Guy Froyen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A novel mutation inJARID1C/SMCX in a patient with autism spectrum disorder (ASD)

(2008) Abidemi Adegbola et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

GABAA Receptor Promoter Hypermethylation in Suicide Brain: Implications for the Involvement of Epigenetic Processes

(2008) Michael O. Poulter et al.   BIOLOGICAL PSYCHIATRY

Epigenetic Regulation in Human Brain—Focus on Histone Lysine Methylation

(2008) Schahram Akbarian et al.   BIOLOGICAL PSYCHIATRY

The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits

(2008) A. M. Allan et al.   HUMAN MOLECULAR GENETICS

Mutations in the chromatin-associated protein ATRX

(2008) Richard J. Gibbons et al.   HUMAN MUTATION

Histone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: Analysis of the National Brain Databank microarray collection

(2007) Rajiv P. Sharma et al.   SCHIZOPHRENIA RESEARCH