Molecular insights on context-specific role of profilin-1 in cell migration

Mena invasive (MenaINV) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM

(2011) Evanthia T. Roussos et al.   CLINICAL & EXPERIMENTAL METASTASIS

Profilin1 is required for glial cell adhesion and radial migration of cerebellar granule neurons

(2011) Jan A Kullmann et al.   EMBO REPORTS

Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer

(2011) E. T. Roussos et al.   JOURNAL OF CELL SCIENCE

Profilin 1 is a Potential Biomarker for Bladder Cancer Aggressiveness

(2011) Jerome Zoidakis et al.   MOLECULAR & CELLULAR PROTEOMICS

Enteropathogenic Escherichia coli Recruits the Cellular Inositol Phosphatase SHIP2 to Regulate Actin-Pedestal Formation

(2010) Katherine Smith et al.   Cell Host & Microbe

Fluorescence Resonance Energy Transfer (FRET)-based Detection of Profilin–VASP Interaction

(2010) Dave Gau et al.   Cellular and Molecular Bioengineering

c-Abl, Lamellipodin, and Ena/VASP Proteins Cooperate in Dorsal Ruffling of Fibroblasts and Axonal Morphogenesis

(2010) Magdalene Michael et al.   CURRENT BIOLOGY

VASP is a processive actin polymerase that requires monomeric actin for barbed end association

(2010) Scott D. Hansen et al.   JOURNAL OF CELL BIOLOGY

Fine-tuning of neuronal architecture requires two profilin isoforms

(2010) K. Michaelsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Profilin1 regulates PI(3,4)P2 and lamellipodin accumulation at the leading edge thus influencing motility of MDA-MB-231 cells

(2010) Y. H. Bae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How depolymerization can promote polymerization: the case of actin and profilin

(2009) Elena G. Yarmola et al.   BIOESSAYS

Profilin 1 is required for abscission during late cytokinesis of chondrocytes

(2009) Ralph T Böttcher et al.   EMBO JOURNAL

Both actin and polyproline interactions of profilin-1 are required for migration, invasion and capillary morphogenesis of vascular endothelial cells

(2009) Zhijie Ding et al.   EXPERIMENTAL CELL RESEARCH

In birds, profilin-2a is ubiquitously expressed and contributes to actin-based motility

(2009) K. Murk et al.   JOURNAL OF CELL SCIENCE

Loss of profilin-1 expression enhances breast cancer cell motility by Ena/VASP proteins

(2009) Yong Ho Bae et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effect of Profilin on Actin Critical Concentration: A Theoretical Analysis

(2008) Elena G. Yarmola et al.   BIOPHYSICAL JOURNAL

Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo

(2008) Sumanta Goswami et al.   CLINICAL & EXPERIMENTAL METASTASIS

A Mena Invasion Isoform Potentiates EGF-Induced Carcinoma Cell Invasion and Metastasis

(2008) Ulrike Philippar et al.   DEVELOPMENTAL CELL

The profilin:actin complex localizes to sites of dynamic actin polymerization at the leading edge of migrating cells and pathogen-induced actin tails

(2008) Yu Li et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Profilin-1 overexpression upregulates PTEN and suppresses AKT activation in breast cancer cells

(2008) Tuhin Das et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Phosphorylation of Profilin by ROCK1 Regulates Polyglutamine Aggregation

(2008) J. Shao et al.   MOLECULAR AND CELLULAR BIOLOGY

Diaphanous-Related Formin 2 and Profilin I Are Required for Gastrulation Cell Movements

(2008) Shih-Lei Lai et al.   PLoS One