Chemico-genetic strategies to inhibit the leukemic potential of threonine aspartase-1

Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia

(2011) R. Montes et al.   BLOOD

A Pharmacologic Inhibitor of the Protease Taspase1 Effectively Inhibits Breast and Brain Tumor Growth

(2011) D. Y. Chen et al.   CANCER RESEARCH

The heterodimerization domains of MLL—FYRN and FYRC—are potential target structures in t(4;11) leukemia

(2011) B Pless et al.   LEUKEMIA

Bioassays to Monitor Taspase1 Function for the Identification of Pharmacogenetic Inhibitors

(2011) Shirley K. Knauer et al.   PLoS One

The AF4{middle dot}MLL fusion protein is capable of inducing ALL in mice without requirement of MLL{middle dot}AF4

(2010) A. Bursen et al.   BLOOD

Taspase1 Functions as a Non-Oncogene Addiction Protease that Coordinates Cancer Cell Proliferation and Apoptosis

(2010) D. Y. Chen et al.   CANCER RESEARCH

Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion

(2008) Lauren P. Saunders et al.   MOLECULAR CANCER THERAPEUTICS